Rapamycin Sirolimus RAPA CAS 53123-88-9 Su'ega ≥98.5% API Falegaosi Ma'a Maualuga
Faumea e maualuga le mama ma mautu lelei
Igoa Vailaau: Rapamycin;Sirolimus;RAPA
CAS: 53123-88-9
Macrolide Immunosuppressive Agent
API Tulaga Maualuga, Gaosiga Fa'apisinisi
Igoa Vailaau | Rapamycin |
Synonyms | Sirolimus;RAPA;AY-22989 |
Numera CAS | 53123-88-9 |
CAT Numera | RF-API59 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i le selau Kilograms |
Fuafua mole | C51H79NO13 |
Molecular Weight | 914.19 |
Lisi Lisi | 183.0~185.0 ℃ |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'u Pa'epa'e po'o le Pa'epa'e Pa'epa'e |
Faailoaina A | Ole alaleo ole IR ole tapenaga o le potassium bromide ole fa'ata'ita'iga o lo'o fa'aalia le maualuga ile galu e tasi e pei o se sauniuniga tutusa o le fa'asologa o fa'asinomaga ile fale. |
Faailoaga B | Ole fusi ole UV ole 95% ethanol sauniuniga ole fa'ata'ita'iga o lo'o fa'aalia le maualuga ile 267nm, 277nm, 288nm e pei o se sauniuniga tutusa o fa'amaumauga ile fale. |
Faailoaina C | O le taimi o le taofiofia o tumutumu mo le trans-ma cis-stereoisomers i le chromatogram o sauniuniga suʻesuʻe e fetaui ma lena i le chromatogram o le sauniuniga masani, e pei ona maua i le suʻega. |
Vaitaimi Mata | -147.0°~ -157.0° |
Ma'imau ile Fa'amago | ≤0.50% |
Toega i luga o le mumu | ≤0.20% |
Metala mamafa | ≤20ppm |
Le mama o le tagata lava ia | ≤1.5% |
Aofa'i Fa'aleaga | ≤2.0% (e le aofia ai Cis-Stereoisomer o Sirolimus) |
Cis-Stereoisomer o Sirolimus | ≤5.0% |
Solvents totoe | |
Ethanol | ≤5000ppm |
Ethyl Acetate | ≤5000ppm |
Cyclohexane | ≤5000ppm |
Acetone | ≤5000ppm |
Dietil Eteru | ≤5000ppm |
Su'ega | ≥98.5% (Fa'atatauina trans- ma cis-stereoisomer o sirolimus i luga o le fa'avae fa'atau) |
Tulaga Su'ega | Pharmacopoeia Saina (CP);Pisinisi Tulaga |
Fa'aoga | Mea Fa'afoma'i Gaoioiga (API) |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
Rapamycin (Sirolimus; AY 22989) o se autophagy activator, o se ituaiga fou o le macrolide immunosuppressive sui ma aafiaga lelei curative, maualalo oona, ma leai nephrotoxicity.E mafai ona fa'aoga e fa'atumauina ai le puipuiga o totoga toto (aemaise i totoga fatuga'o) e fa'aitiitia ai le te'ena o le immunological pe a mae'a taotoga o totoga.