Remdesivir Intermediate CAS 1911578-98-7 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate
Gaosi Fa'atauga Fa'atauga Remdesivir ma Feso'ota'i Fesoota'iga ma le Tulaga Maualuga
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Igoa Vailaau | 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate |
Synonyms | N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester;Remdesivir Intermediate;Remdesivir-001;Remdesivir Le mama 21 |
Numera CAS | 1911578-98-7 |
CAT Numera | RF-PI303 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i le selau Kilograms |
Fuafua mole | C21H27N2O7P |
Molecular Weight | 495.38 |
Malosi | 1.2g/cm3 |
Lisi Lisi | 92.0~96.0 ℃(malamalama) |
Fa'apuna | 356.7 ℃ ile 760 mmHg |
Tulaga Va'a | La'uina i lalo ole vevela ole ambient |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e i le Pa'epa'e Pa'epa'e |
Alaleo Infrared | E tusa ma le Fauga |
Mama | ≥99.0% |
Ma'imau ile Fa'amago | ≤0.50% |
Le mama nofofua | ≤0.50% |
Aofa'i Fa'aleaga | ≤1.0% |
Metala mamafa | ≤20ppm |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | Vaitaimi ole Remdesivir (CAS 1809249-37-3) |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate (CAS 1911578-98-7) o se faʻauluuluga autu autu i le sauniuniga o Remdesivir faʻatatau analogs.Remdesivir o se monophosphoramidate prodrug o se adenosine analog, o se suʻesuʻega lautele-alaala antiviral sui ma in vitro gaoioiga e faasaga i le SARS coronavirus, MERS coronavirus ma, talu ai nei, Covid-19.O le Remdesivir sa masani ona atiaʻe e fai ma togafitiga mo faʻamaʻi filovirus pei ole faʻamaʻi o le Ebola virus poʻo le virus Marburg.Mulimuli ane, na maua le Remdesivir o loʻo faʻaalia le antiviral antiviral e faasaga i isi faʻamaʻi RNA e tasi e pei o le respiratory syncytial virus, Nipah virus, Hendra virus, Junin virus, Lassa fever virus ma le coronaviruses (e aofia ai MERS ma SARS viruses).Talu ai nei o loʻo suʻesuʻeina o se vailaʻau faʻamaonia mo le togafitia o le COVID-19 (faʻamaʻi fou o le SARS).Remdesivir, atiae e Gilead Sciences, o se adenosine prodrug e metabolizes i lona tulaga galue GS-441524 lea e faʻalavelave i le gaioiga o viral RNA-faalagolago RNA polymerase ma aloese mai le faʻamaonia e viral exoribonuclease (ExoN), ma mafua ai le faʻaititia o le viral RNA gaosiga.