Rifamycin S CAS 13553-79-2 Mama>97.5% (HPLC) Falegaosimea
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Igoa Vailaau | Rifamycin S |
Synonyms | 1,4-Dideoxy-1,4-Dihydro-1,4-Dioxorifamycin;Rifaximin EP Le mama E |
Numera CAS | 13553-79-2 |
CAT Numera | RF-PI2058 |
Tulaga Fa'asoa | I Fa'atauga, Gaosiga Gafatia 500MT/Tausaga |
Fuafua mole | C37H45NO12 |
Molecular Weight | 695.76 |
Ma'ale'ale | Ma'ale'ale vevela |
Ta'amilosaga Fa'apitoa [α]20/D | +451.0°~+500.0° (C=0.1 i le MeOH) |
Lisi Lisi | 201℃ |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Samasama po'o Lanini Samasama Crystalline Powder |
Ma'imau ile Fa'amago | ≤3.00%(4h 100℃) |
Toega i luga o le mumu | ≤0.50% |
Mea Fa'atatau | |
Rifamycin-O | ≤0.50% |
Rifamycin-B | ≤0.50% |
Tasi Tulaga | ≤1.00% |
Aofa'i Fa'aleaga | ≤2.50% |
Mama / Suʻesuʻega Metotia | >97.5% (HPLC) |
Alaleo Infrared | E tusa ma le Fauga |
Proton NMR Alaleo | E tusa ma le Fauga |
Tulaga Su'ega | Pisinisi Tulaga |
Ola Fa'asa | 24 Masina Mai le Aso Gauai pe a teu lelei |
Fa'aoga | Ose Intermediate Autu mo le fa'aogaina o vaila'au Rifamycin |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
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Rifamycin S (CAS: 13553-79-2) ose vaega autu mo le tuufaatasia o vailaau rifamycin.Rifamycin S o se vailaʻau semi-synthetic.Rifamycin S ose quinone ma se antibiotic agnet e faasaga i siama Gram-positive (e aofia ai le MRSA).Rifamycin S o le oxidized fomu o se faiga oxidation-faʻaitiitia toe faʻafouina e aofia ai electrons lua.Rifamycin S fa'atupuina ituaiga okesene fa'afofoga (ROS) ma fa'alavelaveina le microsomal lipid peroxidation.Rifamycin S e mafai ona faʻaaogaina mo le mamapala ma le lepela.O le rifamycins o se vaega o vailaʻau faʻamaʻi e maua mai i le faʻafefe mai aganuu a Streptomycesmediterranei.E iai i le vasega o vailaau fa'ama'i e ta'ua o leansamycins o lo'o iai se mama macrocyclic e feso'ota'i i tulaga e lua e le'i soso'o o se nucleus manogi.O le rifamycins ma le tele o latou semisynthetic derivative e iai le lautele o alaleo o gaioiga antimicrobial.E sili atu lo latou malosi e tetee atu i siama Gram-positive ma M. tuberculosis.Peita'i, o lo'o fa'agaoioi fo'i e fa'asagatau i siama Gram-negative ma le tele o fa'ama'i.O le Rifampin, o se mea e maua mai i le Rifamycin B, na faʻasaʻolotoina e avea ma sui o le antitubercular i le Iunaite Setete i le 1971. O se faʻataʻitaʻiga semisynthetic, rifabutin, na faʻamaonia i le 1992 mo le togafitia o faʻamaʻi pipisi o le mycobacterial atypical.
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