Rosuvastatin Calcium CAS 147098-20-2 Su'ega 98.5% ~ 102.0% API Falegaosi Mamalu Maualuga
Tuuina atu ma le mama maualuga ma le mautu lelei
Rosuvastatin Calcium
CAS: 147098-20-2
Oloa Faapisinisi
Igoa Vailaau | Rosuvastatin Calcium |
Synonyms | ZD 4522 Calcium;(E)-6-[4-(4-Fluorophenyl)-6-Isopropyl-2-(Methyl-Methylsulfonyl-amino)pyrimidin-5-yl]-2,4-Dihydroxy-hex-5-Enoate;(6E)-7-{4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(methylsulfonyl) amino]pyrimidin-5-yl}-3,5-Dihydroxyhept-6-Enoic Acid |
Numera CAS | 147098-20-2 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C44H54CaF2N6O12S2 |
Molecular Weight | 1001.14 |
Lisi Lisi | 122℃ |
Tulaga Va'a | La'uina i lalo ole vevela ole ambient |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e i le Pa'epa'e Pa'epa'e |
Ta'amilosaga Fa'apitoa | +17.0° ~ +21.0° |
Fa'ailoaga | T. Fa'amalieina le Manaoga B. UV: λmax=243nm C. IR: E tutusa ma Reference Substance D. X-Ray: Tutusa ma Fa'amatalaga Mea |
Klorida | ≤0.10% |
Sulphate | ≤0.10% |
Enantiomer | ≤0.15% |
Ole mea ole calcium | 3.5%~4.5% |
Mea Fa'atatau | |
Diastereomer | ≤0.15% |
5-Oxo-Rosucastatin | ≤0.15% |
Fa'aleagaina o Ata 1 | ≤0.15% |
Fa'aleagaina o Ata 2 | ≤0.15% |
Rosuvastatin Lactone | ≤0.15% |
Rosuvastatin Methyl Ester | ≤0.15% |
Rosuvastatin Isoamyl Ester | ≤0.15% |
So'o se Fa'aleaga Le Malamalama | ≤0.10% |
Aofa'i Fa'aleaga | ≤0.75% |
Susū (KF) | ≤3.0% |
Uamea Mamafa | ≤20ppm |
Isoamil Bromide | ≤37.5ppm |
Solvents totoe | |
Ethyl Eteru | ≤300ppm |
Acetonitrile | ≤410ppm |
Isoamil Alcohol | ≤5000ppm |
DMF | ≤880ppm |
Su'ega | 98.5% ~ 102.0% (fa'atulagaina i luga ole fa'avae anhydrous) |
Tulaga Su'ega | Atina'e Atina'e;BP/USP/EP Standard |
Fa'aoga | API |
afifi: Fagu, paelo, pusa pa'u pepa, 25kg/Paila, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu
Rosuvastatin Calcium (CAS: 147098-20-2) o se vailaʻau anti-hyperlipidemia o loʻo aʻafia i le inhibitor o le HMG-CoA reductase na atinaʻe manuia e le kamupani Peretania AstraZeneca.E fetaui lelei mo le togafitia o faʻalavelave faʻaletonu o le lipid, e aofia ai le hypercholesterolemia, faʻalavelave faʻafefeteina o le lipid ma le hypertriglyceridemia faigofie.Rosuvastatin Calcium (CAS: 147098-20-2) o loʻo lisiina o vailaʻau faʻamalosi sili ona malosi ma sili ona atoatoa ua ulufale atu i le maketi mo le faʻaitiitia o le lipid ma le fetuunaiga.Pe a faatusatusa i le atorvastatin lea ua lauiloa i le taimi nei ma le aoga sili ona lelei i le lalolagi, e sili atu lona aafiaga o le faaitiitia o le maualuga o le LDL cholesterol ma faateleina le maualuga o le lipoprotein maualuga.E le gata i lea, o loʻo i ai se faʻapalepale sili atu, maualalo aʻafiaga ma uiga faʻapitoa pharmacokinetic ma le afa-ola e uiga i le 20h.