(S)-3-Aminoquinuclidine Dihydrochloride CAS 119904-90-4 Mama ≥99.0% ee≥99.0% Palonosetron Hydrochloride Intermediate
Sapalai Pisinisi Palonosetron Hydrochloride ma Fesoota'iga Fa'atatau:
(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R)-1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API
| Igoa Vailaau | (S)-3-Aminoquinuclidine Dihydrochloride |
| Synonyms | (S)-(-)-3-Aminoquinuclidine 2 HCL |
| Numera CAS | 119904-90-4 |
| CAT Numera | RF-CC112 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
| Fuafua mole | C7H16Cl2N2 |
| Molecular Weight | 199.12 |
| Malosi | 1.24g/cm3 |
| Lisi Lisi | 260℃ |
| Fa'apuna | 470.4℃ ile 760mmHg |
| Solubility i le Vai | Solu |
| Tulaga Va'a | La'uina i lalo ole vevela ole ambient |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Pa'epa'e i le Malamalama Samasama Crystalline Pa'u |
| IR | Absorption Spectra e ogatasi ma le Fa'asinomaga |
| Taliga o le Chloride | Tali Lelei |
| Mama (HPLC) | ≥98.0% |
| Ma'imau ile Fa'amago | ≤0.50% |
| Ta'amilosaga Fa'apitoa [α]D20 | -22.0°~ -26.0° (C=1, H2O) |
| Metala mamafa | ≤20ppm |
| Teuga | 5-8 ℃ Ea malulu |
| Tulaga Su'ega | Pisinisi Tulaga |
| Fa'aoga | Palonosetron Hydrochloride (CAS: 135729-62-3) Vaitaimi |
(S)-3-Aminoquinuclidine Dihydrochloride (CAS: 119904-90-4) Auala fa'akomepiuta
afifi: Fagu, Ato pepa alumini, Pusa Pusa, 25kg / Paʻu, poʻo e tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua ma tuʻuina atu (S) -3-Aminoquinuclidine Dihydrochloride (CAS: 2133-40-6) faʻatasi ai ma le maualuga.O se vailaʻau faʻapitoa e masani lava i le tuʻufaʻatasia o le Palonosetron Hydrochloride (CAS: 135729-62-3).
Palonosetron Hydrochloride (CAS: 135729-62-3) o se vailaʻau e faʻafefe ai le nausea ma le puaʻi, o se ituaiga fou e sili ona filifilia, maualuga-affinity 5-HT3 receptor antagonist e mafai ona poloka le vomiting reflex center peripheral neurons presynaptic 5-HT.O le fiafia o le tagata faʻafeiloaʻi e aʻafia tonu ai le fatugalemu o le tino i le 5-HT.O le fiafiaga o le talipupuni faʻamalosi e mafua mai i le matafaioi a le vagal afferent nerve i le isi itu, poloka le faʻaiʻuga o le nerve vagus i totonu o le gutu, puipuia faʻailoga i le 5-HT.Receptor trigger zone e mafai ona faʻaitiitia ai le aʻafiaga o le faʻavauvau ma le puaʻi.Falema'i tutotonu mo togafitiga o le ma'i tu'ina emetogenic chemotherapy fa'aoso fa'atuai ma pua'i.Ona o le maualuga o lona aʻafiaga, itiiti aʻafiaga, umi afa-ola (tusa ma le 40 h), laʻititi fua, ma isi mea, ua tosina mai ai le tele o le gauai.Faatasi ai ma le 1,2,3,4-tetrahydro-1-naphthoic acid e avea ma mea amata, o le vaeluaina, amination, faʻaitiitia, cyclization, masima o le palonosetron hydrochloride granisetron.O suʻesuʻega faʻafomaʻi na faʻaalia ai e mafai ona faʻaoga saogalemu le palonosetron i corticosteroids, analgesics, antiemetics, antispasmodics ma anticholinergic vailaʻau e pei o mea amata, le vaeluaina, amination, faʻaitiitia, cyclization, masima o le palonosetron hydrochloride granisetron.
