Sitagliptin CAS 486460-32-6 Mama >99.0% (HPLC) API Falegaosi Ma'a Maualuga
Tuuina atu le Sitagliptin Phosphate Monohydrate Fesoʻotaʻi Faʻatasi:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
Igoa Vailaau | Sitagliptin |
Synonyms | (3R)-3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazin-7-yl]-4- (2,4,5-trifluorophenyl)butan-1-tasi |
Numera CAS | 486460-32-6 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C16H15F6N5O |
Molecular Weight | 407.31 |
Lisi Lisi | 114.0~115.0 ℃ |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e i le Pa'u Pa'epa'e Pa'epa'e |
Faailoaina e le HPLC | Ole Taimi Fa'atumauina ole Fa'ata'ita'iga e fetaui ma Fa'amaumauga Fa'asinomaga |
Ma'imau ile Fa'amago | <1.0% |
Toega i luga o le mumu | <0.20% |
Mea Fa'atatau | |
So'o se Fa'aleaga Ta'itasi | <0.50% |
Aofa'i Fa'aleaga | <1.0% |
Mama | >99.0% (HPLC) |
Enantiomeric Mama | <0.50% |
Metala mamafa | <20ppm |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | API;Ituaiga II Ma'isuka Mellitus |
afifi: Fagu, Ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu.
Sitagliptin (CAS: 486460-32-6), o se ituaiga fou o vailaʻau faʻamaʻi, Sitagliptin Phosphate e iai le lelei o le faʻalagolago i le kulukose, faʻaitiitia le faʻaogaina o le hypoglycemic, faʻateleina le faʻaogaina e aunoa ma le hypoglycemia, faʻamalieina lelei le fiaʻai, ma leai ni aʻafiaga e pei o le nausea, pua'i, edema ma le mamafa o le tino.Sitagliptin phosphate o se togafitiga faʻasaina e tasi i tagata mamaʻi e maua i le maʻisuka ituaiga II e mafai ona faʻaitiitia ai le maualuga o le hemoglobin glycosylated (HbA1c).O le dipeptidyl peptidase-4 (DPP-4) inhibitor, lea e mafai ona faʻaleleia le malosi o le tino o le tagata e faʻaitiitia ai le maualuga o le kulukose toto.Sitagliptin na atiaʻe e Merck & Co. ma faʻamaonia mo le faʻaaogaina faafomaʻi i le Iunaite Setete i le 2006.