Sitagliptin Phosphate Monohydrate CAS 654671-77-9 Mama>99.0% (HPLC) API Falegaosi Mea Maualuluga

Fa'amatalaga Puupuu:

Igoa vaila'au: Sitagliptin Phosphate Monohydrate

CAS: 654671-77-9

Mama: >99.0% (HPLC i luga ole fa'amamago)

Fa'aaliga: Pa'epa'e i le Pa'u Pa'epa'e Pa'epa'e

Mo togafitiga o le maʻisuka ituaiga II

API Tulaga Maualuga, Gaosiga Fa'apisinisi

E-Mail: alvin@ruifuchem.com

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Tuuina atu le Sitagliptin Phosphate Monohydrate Fesoʻotaʻi Faʻatasi:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3

Meatotino tau vailaau:

Igoa Vailaau	Sitagliptin Phosphate Monohydrate
Synonyms	(R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4- (2,4,5-trifluorophenyl)butan-1-tasi phosphate monohydrate
Numera CAS	654671-77-9
Tulaga Fa'asoa	I Fa'atauga, Oloa Fua e O'o i Tone
Fuafua mole	C16H20F6N5O6P
Molecular Weight	523.3240802
Lisi Lisi	202.0~204.0 ℃
Suavai Solubility	Solu i le Vai
Ta'amilosaga Fa'apitoa	-18.0°~-23.0° (C=1, Vai)
Fa'ailoga	Ruifu Chemical

Fa'amatalaga:

Aitema	Fa'amatalaga
Fa'aaliga	Pa'epa'e i le Pa'u Pa'epa'e Pa'epa'e
Faailoaina e le HPLC	Ole taimi ole fa'atumauina ole fa'ata'ita'iga e fetaui lelei ma tulaga fa'asino
IR-Infrared Spectrum	Ole alaleo ole IR absorption ole fa'ata'ita'iga e tatau ona ogatasi ma alaleo masani
Phosphate	E usitaia
Mama / Suʻesuʻega Metotia	>99.0% (HPLC ile fa'amamago)
Suavai (KF)	3.3%~4.4%
Toega i luga o le mumu	≤0.20%
Sulphate	≤0.02%
Klorida	≤0.05%
Chiral Le mama	<0.50%
Mea Fa'atatau
Le mama nofofua	<0.50%
Aofa'i Fa'aleaga	<1.0%
Ethyl Acetate	<0.50%
Metala mamafa	<20ppm
Tulaga Su'ega	Pisinisi Tulaga
Fa'aoga	Vailaau Fa'atekonolosi

Paket & Teuina:

afifi: Fagu, Ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau.

Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu.

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Talosaga:

Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9), o se vailaʻau fou mo togafitiga o le maʻisuka ituaiga 2.I le masina o Aukuso 2009, na faʻamaonia ai le vailaʻau e le Iuni a Europa e avea o se vailaʻau muamua mo le togafitiga o le maʻisuka ituaiga 2.O le Sitagliptin Phosphate o le dipeptidyl peptidase-IV inhibitor muamua na faʻatagaina e le FDA e faʻaaogaina i togafitiga o le maʻisuka ituaiga 2 i le mamao, i lalo o le igoa fefaʻatauaʻiga Januvia.Dipeptidylpeptidase Ⅳ (DPP-Ⅳ) vave ma lelei faʻaleagaina le GLP-1, GLP-1, o le faʻamalosia sili ona aoga o le gaosiga o le inisalini ma le faʻalilolilo O le mea lea, o le taofiofia o le DPP-IV e mafai ona faʻaleleia ai le matafaioi a le GLP-1 endogenous, ma faʻateleina ai le toto. maualuga ole inisalini, e fa'aitiitia ai ma fa'atumauina le maualuga ole kulukose ile toto ile ma'i suka.I le taimi nei, ua faʻamaonia e vailaʻau o le DPP-IV inhibitor o se ituaiga fou o vailaʻau e puipuia ai le maʻisuka, ma o faʻaiʻuga a le falemaʻi e faʻaalia ai o vailaʻau e iai se aafiaga lelei o le hypoglycemic.Talu ai ona o le GLP-1 o loʻo faʻalagolago i le kulukose i le faʻalauiloaina o le gaosiga o le inisalini ma le faʻamalo, o aʻafiaga masani e pei o le hypoglycemia ma le paʻu mamafa e mafua mai i le faʻaaogaina o vailaʻau faʻamaʻi e le tupu.