Sodium Valproate (VPA) CAS 1069-66-5 API Falegaosi Mamalu Maualuga
Gaosi Mea Fa'atauga Sapalai ma le Mamalu Maualuga ma Tulaga Tulaga Lelei
Igoa Vailaau: Sodium Valproate (VPA)
CAS: 1069-66-5
Igoa Vailaau | Sodium Valproate |
Synonyms | VPA;Valproic Acid Sodium Salt;Sodium 2-Propylpentanoate |
Numera CAS | 1069-66-5 |
CAT Numera | RF-API14 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C8H15NaO2 |
Molecular Weight | 166.20 |
Lisi Lisi | 300℃ |
Malosi | 1.0803 g/cm3 |
Suavai Solubility | Solu i le Vai |
Tulaga Va'a | I lalo ole Temperature Ambient |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e po'o Toeitiiti Pa'epa'e Pa'u tioata, Hygroscopic |
Fa'ailoaga | Alaleo Infrared I le RT faʻatusatusaga Tali a le Masima Sodium |
Solubility | E matua solu i le vai, solu fua ile ethanol |
Acidity po'o Alkalinity | E tusa ai ma le EP Criterions |
Malamalama & Lanu o Fofo | E tusa ai ma le EP Criterions |
Metala mamafa | ≤20ppm |
Sulfates | ≤200ppm |
Klorida | ≤200ppm |
Ma'imau ile Fa'amago | ≤2.0% |
Soo se mea le mama | ≤0.10% (GC) |
Aofa'i Fa'aleaga | ≤0.30% (GC) |
Su'ega | 98.5%~101.0% (Titration) |
Tulaga Su'ega | Pharmacopeia Europa (EP) |
Fa'aoga | Mea Fa'afoma'i Gaoioiga (API) |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
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Sodium Valproate (CAS: 1069-66-5) ose vaila'au fa'atosina ma aoga mo le fa'atonutonuina o le to'esea ma le fa'atosina lautele fa'atosina-clonic faoa faamalosi.Valproic acid sodium salt (Sodium Valproate) o le histone deacetylase (HDAC) inhibitor, faatasi ai ma le IC50 i le va o le 0.5 ma le 2 mM, e taofia ai foi le HDAC1 (IC50, 400 μM), ma faʻaosofia ai le faʻaleagaina o le proteasomal o le HDAC2.Valproic acid sodium salt e fa'agaoioi ai le fa'ailoga Notch1 ma taofia le fa'atuputeleina i sela laiti o le kanesa mama (SCLC).Sodium Valproate (CAS: 1069-66-5) o loʻo faʻaaogaina i le togafitiga o le epilepsy, maʻi pipili ma le puipuia o le ulu o le ulu.
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