Telmisartan CAS 144701-48-4 Mama >99.5% (HPLC) API Falegaosi
Ruifu Chemical Supply Telmisartan Intermediates ma maualuga mama
Telmisartan CAS 144701-48-4
Methyl 2-(p-Tolyl)benzoate CAS 114772-34-8
2-(p-Tolyl)benzoic Acid CAS 7148-03-0
Telmisartan Benzimidazole Acid CAS 152628-03-0
Telmisartan Methyl Ester CAS 528560-93-2
Methyl 2-[4-(Bromomethyl)phenyl]benzoate CAS 114772-38-2
Methyl 4-(Butyrylamino)-3-Methyl-5-Nitrobenzoate CAS 152628-01-8
2-n-Propyl-4-Methyl-6-(1-Methylbenzimidazole-2-yl)benzimidazole CAS 152628-02-9
Igoa Vailaau | Telmisartan |
Synonyms | 4'-[[4-Methyl-6-(1-Methyl-1H-Benzimidazol-2-yl) -2-Propyl-1H-Benzimidazol-1-yl]methyl]biphenyl-2-Carboxylic Acid;4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-Benzimidazol]-1'-yl)methyl]-[1,1'-Biphenyl]-2-Carboxylic Acid |
Numera CAS | 144701-48-4 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C33H30N4O2 |
Molecular Weight | 514.63 |
Lisi Lisi | 261.0~263.0 ℃ |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'u Pa'epa'e po'o le Pa'epa'e Pa'epa'e |
Sogisogi | Uiga |
Solubility | Fa'ase'e solu i le Methylene Chloride, La'u Souble i le Methanol, La'ititi le solu i le Suavai, Fa'amuta ile 1M Solution Hydroxide |
IR Identification | E tatau ona fetaui ma le RS Infrared Absorption |
Fa'ailoga HPLC | Taimi Fa'atumauina o Tulaga Tele e Tatau Ona Fa'atatau ile RS |
Mama / Suʻesuʻega Metotia | >99.5% (HPLC) |
Ma'imau ile Fa'amago | <1.00% |
Toega i luga o le mumu | <0.10% |
Mea Fa'atatau | |
Telmisartan Related Compound A | <0.10% |
Telmisartan Amide | <0.10% |
Telmisartan Related Compound B | <0.10% |
Telmisartan diacide | <0.10% |
Telmisartan Tert-Butyl Ester | <0.20% |
Telmisartan Le iloa le mama | <0.20% |
Le fa'amamafaina le mama | <0.10% |
Aofa'i Fa'aleaga | <1.00% |
Solvents totoe | |
Methanol | <0.30% |
Ethanol | <0.50% |
Methylene Dichloride | <0.06% |
n-Hexane | <0.029% |
Acetic Acid Ethyl Ester | <0.50% |
Toluene | <0.089% |
Acetic Acid | <0.50% |
Metala mamafa | <10ppm |
Arsenic (As) | <1.00ppm |
Ta'ita'i (Pb) | <1.00ppm |
Cadmium (Cd) | <1.00ppm |
Lapo'a La'au | D90 Le sili atu i le 15μm |
To'atele (g/cc) | 0.11~0.20 |
Ta'a'ele'ele (g/cc) | 0.22~0.30 |
Pesticide o totoe | Le lelei |
Faitauga o Papatusi Aofa'i | <1000cfu/g |
Faafefete & Mold | <100cfu/g |
E. Coli | Le lelei |
Salmonella | Le lelei |
Tulaga Su'ega | Atina'e Atina'e;USP 41 Fa'atonu |
Fa'aoga | API |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
Telmisartan (CAS: 144701-48-4) o le benzimidazole fa'atosina ma le le-peptide angiotensin II fa'afeagai tali fa'atasi ma meatotino antihypertensive.O le Telmisartan e faʻafefeteina le angiotensin II o loʻo fusifusia i le AT1 subtype receptor, o loʻo i totonu o le maso lamolemole vascular ma le gland adrenal.O le antagonism e mafua ai le vasodilation ma taofia ai le gaosiga o le aldosterone o le angiotensin II-mediated, lea e oʻo atu ai i le faʻaitiitia o le sodium ma le vai faʻapea foʻi ma le faʻateleina o le potassium excretion e oʻo atu ai i le faʻaitiitia o le toto maualuga.Telmisartan o se ituaiga fou o fualaau o le toto maualuga, e faʻaaogaina naʻo ia pe faʻatasi ma isi vasega o antihypertensives mo togafitiga o le toto maualuga.Telmisartan na muai faʻatulagaina e le kamupani Siamani vailaʻau Boehringer Ingelheim;na maua ai le pateni Siamani EP502,314 i le 1991, na muamua faʻatagaina e ulufale i le maketi a Amerika ia Novema 1998, ona ulufale ai lea i Siamani, Filipaina, Ausetalia, Peleseuma, Peretania, ma isi maketi.