Tenofovir Alafenamide Hemifumarate TAF CAS 1392275-56-7 API Falegaosi Anti-HIV Tulaga Maualuga

Fa'amatalaga Puupuu:

Igoa: Tenofovir Alafenamide Hemifumarate (TAF)

CAS: 1392275-56-7

Pa'epa'e i le Toeititi lava Pa'epa'e tioata po'o le pauta tioata

Su'ega: 98.0%~102.0%

O se vailaʻau mo Tenofovir, faʻaaogaina i togafitiga faʻatasi mo togafitiga o le HIV-1 Infection

Tulaga Maualuga, Gaosiga Fa'apisinisi

Inquiry: alvin@ruifuchem.com

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Fa'amatalaga Oloa

Oloa Fa'atatau

Faailoga o oloa

Fa'amatalaga:

Fa'atauga Fa'apisinisi Tenofovir Feso'ota'i Vaitaimi:
Tenofovir CAS: 147127-20-6
Tenofovir Disoproxil Fumarate CAS 202138-50-9
Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
Chloromethyl Isopropyl Carbonate CAS 35180-01-9
Diethyl (p-Toluenesulfonyloxymethyl)phosphonate CAS 31618-90-3
(R)-(+)-Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl)adenine CAS 14047-28-0
Diethyl (Hydroxymethyl)phosphonate CAS 3084-40-0
Adenine CAS 73-24-5

Meatotino tau vailaau:

Igoa Vailaau	Tenofovir Alafenamide Hemifumarate
Synonyms	TAF;GS-7340 Hemifumarate
Numera CAS	1392275-56-7
CAT Numera	RF-API91
Tulaga Fa'asoa	I Fa'atauga, Oloa Fua e O'o i le selau Kilograms
Fuafua mole	C25H33N6O9P
Molecular Weight	592.55
Teuga vevela	Faamaufa'ailoga i le mago, potu vevela
Fa'ailoga	Ruifu Chemical

Fa'amatalaga:

Aitema	Fa'amatalaga
Fa'aaliga	Pa'epa'e i le Toeititi lava Pa'epa'e tioata po'o le pauta tioata
Solubility	Solu i le Dimethylformamide, ma Methanol;Fa'ase'e solu i le vai ma le THF;Laititi solu i le Acetonitrile ma le mafai ona solu i le Dichloromethane ma Toluene
Faailoaina A	O le IR absorption spectra e tatau ona ogatasi ma le faasinomaga
Faailoaga B	Ole taimi fa'atumauina ole tumutumu tele ole fofo fa'ata'ita'i ile chromatogram e fa'atatau i mea e fa'atatau ile vaifofo fa'asino.
Faailoaina C	Ole taimi ole fa'atumauina ole Fumaric Acid ole pito maualuga ile chromatogram e fa'atatau ile mea e fa'atatau ile tumutumu ole fa'asinomaga.
Suavai (e KF)	≤1.0%
Malamalama ole Fofo	Ole mea masani e leai ni mea e iloa ile 2% (w/v) ole fa'amalamalamaga ole Methanol Solution
Solvent totoe
Acetonitrile	≤410ppm
Ethanol	≤5000ppm
Dichloromethane	≤600ppm
Toluene	≤890ppm
Toega i luga o le mumu	≤0.10%
Metala mamafa	≤20ppm
Mea Fa'atatau
PMPA	≤1.0%
PMPA Anhydride	≤0.75%
Nofofua Phenyl PMPA	≤1.0%
So'o se mea le mama e le o ta'ua	≤0.15%
Aofa'i Fa'aleaga	≤2.0%
Isomer	≤1.0%
O lo'o iai le Fumaric Acid	9.0% ~ 13.0% (i luga o le anhydrous faavae)
Tapulaa Microbial
Aofa'i Aerobic Microbial Faitau	≤1000CFU/g
Fa'afefete Aofa'i ma Fa'ailoga Fa'ailoga	≤100CFU/g
Escherichia Coli	Toesea
Su'ega	98.0% ~ 102.0% (i luga o le anhydrous ma solvent-saoloto faavae)
Tulaga Su'ega	Pisinisi Tulaga

Paket & Teuina:

afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.

Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.

Tulaga lelei:

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Talosaga:

Tenofovir Alafenamide Hemifumarate (TAF, GS-7340 hemifumarate), CAS 1392275-56-7, o se nucleotide reverse transcriptase inhibitor (NRTIs) ma se novel prodrug of Tenofovir (TFV).O le polokaina o le reverse transcriptase, o le TAF e taofia ai le fa'ateleina o le HIV ma mafai ai ona fa'aitiitia le aofa'i ole HIV ile tino.O le Tenofovir alafenamide o se vailaʻau faʻamalosi, o lona uiga o se vailaʻau le aoga.I totonu o le tino, ua liua le tenofovir alafenamide i le Tenofovir diphosphate (TFV-DP).Tenofovir Alafenamide Fumarate na faamaonia ia Novema 2015 mo togafitiga ole HIV-1.