Tenofovir Disoproxil Fumarate CAS 202138-50-9 Su'ega 98.0%~102.0% API Falegaosi
Fa'atauga Fa'apisinisi Tenofovir Feso'ota'i Vaitaimi:
Tenofovir CAS: 147127-20-6
Tenofovir Disoproxil Fumarate CAS 202138-50-9
Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
Chloromethyl Isopropyl Carbonate CAS 35180-01-9
Diethyl (p-Toluenesulfonyloxymethyl)phosphonate CAS 31618-90-3
(R)-(+)-Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl)adenine CAS 14047-28-0
Diethyl (Hydroxymethyl)phosphonate CAS 3084-40-0
Adenine CAS 73-24-5
Igoa Vailaau | Tenofovir Disoproxil Fumarate |
Synonyms | Tenofovir DF;Bis(POC)-PMPA Fumarate;GS 4331 Fumarate |
Numera CAS | 202138-50-9 |
CAT Numera | RF-API106 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C23H34N5O14P |
Molecular Weight | 635.52 |
Lisi Lisi | 113.0 i le 115.0 ℃ |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e po'o Toeitiiti Pa'epa'e Pa'epa'e |
Faailoaina A | Ole Alaleo ole IR e ogatasi ma Fa'amaumauga Fa'asinomaga |
Faailoaga B | O le taimi o le taofiga o le tumutumu tele mai le faʻataʻitaʻiga fofo e fetaui ma le tulaga o le vaifofo tulaga, e pei ona maua i le suʻega |
Su'ega | 98.0%~102.0% (i luga ole fa'avae) |
Vai | ≤1.0% |
Fumaric Acid | 17.5%~19.0% |
Toega i luga o le mumu | ≤0.20% |
Metala mamafa | ≤20ppm |
Chloromethyl Isopropyl Carbonate | ≤0.15% |
Mea Fa'atatau | |
Tenofovir | ≤0.15% |
Adenine | ≤0.15% |
Tenofovir Isoproxi Monoester | ≤1.0% |
Tenofovir Disoproxil Ethyl Ester | ≤0.15% |
Tenofovir Isopropyl Isoproxil | ≤0.30% |
Tenofovir Disoproxil Carbamate | ≤0.15% |
Tenofovir Disproxil | ≤0.15% |
So'o se Fa'aleaga Ta'itasi | ≤0.10% |
Aofa'i Fa'aleaga | ≤2.0% |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | API |
afifi: Fagu, Ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu.
Tenofovir Disoproxil Fumarate (CAS: 202138-50-9), o se vailaʻau o le tenofovir (Igoa Fefaʻatauaʻiga: Viread) na atiaʻe e Gilead Sciences, o se ituaiga nucleotide-analogues antiretroviral drugs, e faʻaaogaina e ala i le galue o le reverse transcriptase inhibitors[nRTIs] , lea e poloka ai le reverse transcriptase, o se enzyme e taua tele i le gaosiga o viral i tagata ua aafia i le HIV.E tatau ona maitauina o le nucleotide reverse transcriptase inhibitor muamua lea na faʻaaogaina mo togafitiga o faʻamaʻi pipisi o le HIV.Tenofovir Disoproxil Fumarate ua liua i le tenofovir in vivo, o se acyclic nucleoside phosphonate[nucleotide] analog o adenosine 5'-monophosphate.E masani ona faʻaaogaina faʻatasi ma isi ituaiga vailaʻau.E le mafai e vaila'au o le HIV ona fofo le HIV/AIDS, ae o le tagofia o vaila'au tu'ufa'atasiga o le HIV [e ta'ua o le HIV regimen] i aso uma e mafai ona fesoasoani ai i tagata o lo'o maua i le HIV ia ola umi, soifua maloloina.Fa'avae i luga o le pepa a le FDA, o le tenofovir disoproxil fumarate e mafai fo'i ona fai mo togafitiga o fa'ama'i pipisi fa'ama'i hepatitis B [HBV] i tagata matutua ma tamaiti e 12 tausaga ma matutua atu.