Tolvaptan CAS 150683-30-0 API Mama >99.0% (HPLC)
Gaosi Mea Fa'atauga Tolvaptan ma Fesoota'iga Fa'atatau:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-tasi CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
Igoa | Tolvaptan |
Igoa Vailaau | N-[4-(9-chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide |
Numera CAS | 150683-30-0 |
CAT Numera | RF-API101 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C26H25ClN2O3 |
Molecular Weight | 448.94 |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e i le Pa'u Pa'epa'e Pa'epa'e |
Faiga Fa'ailoa | IR, HPLC |
Solubility | Solu i le Benzyl Alcohol ma Methanol ae e le mafai ona solu i le vai ma le Hexane. |
Mama / Suʻesuʻega Metotia | >99.0% (HPLC) |
Lisi Lisi | 219.0~222.0 ℃ |
Ma'imau ile Fa'amago | <0.50% |
Toega i luga o le mumu | <0.10% |
Le mama nofofua | <0.50% |
Aofa'i Fa'aleaga | <1.00% |
Metala mamafa | ≤20ppm |
Solvents totoe | Faʻafeiloaʻi le Faʻamatalaga |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | API;Vailaau Fa'atekonolosi |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
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Tolvaptan (CAS: 150683-30-0), e taʻua foi o le OPC-41061, o se tagata faʻatauvaʻa faʻatauvaa arginine vasopressin receptor 2 faʻaaogaina e togafitia ai le hyponatremia (maualalo o le toto sodium maualuga) e fesoʻotaʻi ma le faʻaletonu o le fatu, cirrhosis, ma le maʻi o le le talafeagai o le antidiuretic hormone (SIADH).Otsuka Pharmaceutical tolvaptan laiseneina i lalo o le igoa tau fefaʻatauaʻiga Samsca ina ua maeʻa ona faʻamaonia e le FDA le vailaʻau ia Me 2009. Ua faʻaalia foi e Tolvaptan le aoga e faasaga i faʻamaʻi fatugaʻo polycystic.I se faʻataʻitaʻiga i le 2004, o le tolvaptan na faʻaaogaina faʻatasi ma vailaʻau faʻaleaganuʻu na matauina e faʻateleina ai le faʻaogaina o le tele o vai ma faʻaleleia le maualuga o le sodium toto i tagata mamaʻi maʻi fatu e aunoa ma le faia o aʻafiaga e pei o le toto maualuga (maualalo le toto) poʻo le hypokalemia (faʻaitiitia le maualuga o le toto o le potassium).O le vailaʻau foʻi na faʻaalia e leai se aʻafiaga leaga i le gaioiga o fatugaʻo.