Tranexamic Acid CAS 1197-18-8 Su'ega 99.0~101.0% (Titration)
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua o Tranexamic Acid (CAS: 1197-18-8) faʻatasi ai ma tulaga maualuga.Ruifu Chemical e mafai ona tuʻuina atu i le lalolagi atoa, tau faʻatauvaʻa, auaunaga sili ona lelei, laʻititi ma tele tele o loʻo avanoa.Fa'atau Tranexamic Acid,Please contact: alvin@ruifuchem.com
| Igoa Vailaau | Tranexamic Acid |
| Synonyms | trans-4-(Aminomethyl)cyclohexanecarboxylic Acid;Trans-Tranexamic Acid;TAMCHA;AMCHA;HAKU;AMCA;t-AMCHA;trans-Amcha |
| Tulaga Fa'asoa | I Fa'atauga, Gaosiga Fa'apisinisi |
| Numera CAS | 1197-18-8 |
| Fuafua mole | C8H15NO2 |
| Molecular Weight | 157.21 g/mol |
| Lisi Lisi | >300℃(malamalama) |
| Maumau | Hygroscopic |
| Suavai Solubility | Solu i le Suavai, Toeititi lava manino |
| COA & MSDS | Avanoa |
| Fa'ata'ita'iga Sa'oloto | Avanoa |
| Amataga | Shanghai, Saina |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga | I'uga |
| Fa'aaliga | Pa'u tioata Pa'epa'e | E usitaia |
| Solubility | Solu i le Suavai ma Glacial Acetic Acid, Toeititi lava Le Solu i le Ethanol ma Acetone (96%) | E usitaia |
| IR Alaleo | E tusa ai ma le Tranexamic Acid CRS | E usitaia |
| pH | 7.0~8.0 | 7.32 |
| Ma'imau ile Fa'amago | <0.50% | 0.06% |
| Sulphate Ash | <0.10% | 0.02% |
| Metala mamafa (Pb) | ≤10ppm | <10ppm |
| Klorida (Cl) | ≤140ppm | <140ppm |
| Arsenic (As) | ≤2ppm | <2ppm |
| Su'ega | 99.0~101.0% (e ala i le Titration) | 99.84% |
| Mea Fa'atatau | ||
| Le mama A | <0.10% | 0% |
| Le mama B | <0.20% | 0.0815% |
| Le mama C | <0.10% | 0.0089% |
| Le mama D | <0.10% | 0.0063% |
| Aofa'i Fa'aleaga | <0.20% (Va'ai A,B) | 0.015% |
| Fa'ai'uga | Ua uma ona fa'ata'ita'iina le oloa ma fa'amalieina fa'atonuga | |
afifi:Fa'ato'aga Fa'alili, Ato pepa alumini, 25kg/Cardboard Drum, pe tusa ai ma mana'oga o tagata fa'atau.
Tulaga teuina:Taofi mau le atigipusa ma teu i totonu o se faleteuoloa malulu, mago (2~8 ℃) ma fa'alelei lelei mai mea e le fetaui.Puipui mai le malamalama ma le susu.
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Tranexamic Acid
C8H15NO2 157.2
trans-4-(Aminomethyl)cyclohexanecarboxylic acid;
Cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans [1197-18-8].
FAAMATALAGA
Tranexamic Acid o loʻo i ai le NLT 99.0% ma le NMT 101.0% o le C8H15NO2, faʻatatau ile faʻamago.
FAATINOGA
• Infrared Absorption <197K>
SU'ESU'EGA
• Taualumaga
Fa'ata'ita'iga fofo: 140 mg o le Tranexamic Acid i le 20 mL o le suka acetic acid.
Titrimetric faiga
(Taga'i Titrimetry <541>.)
Auala: Fa'asaga sa'o
Titrant: 0.1 N perchloric acid VS
Su'esu'ega pito: Potentiometric
Iloiloga
Fa'ata'ita'iga: Fa'ata'ita'iga fofo
Fa'asusu i le 0.1 N perchloric acid VS, fuafua le pito i'uga potentiometrically.Faia se titration avanoa.
O mL ta'itasi o le 0.1 N perchloric acid e tutusa ma le 15.72 mg o le C8H15NO2.
Tulaga talia: 99.0% -101.0% ile fa'amamago
LELEI
Fa'aleaga Fa'aletino
• Toega i luga o le mumu <281>: NMT 0.1%;1-g faʻataʻitaʻiga faʻaaogaina
• Metala Mamafa, Metotia II <231>: NMT 10 ppm
• Chloride ma Sulfate, Chloride <221>: O se vaega 0.51-g e le sili atu le chloride nai lo le tutusa ma le 0.1 mL o le 0.020 N hydrochloric acid (0.014%).
Oona Fa'aleaga
• Taualumaga
Vaega feavea'i: Fa'amuta le 11.0 g o le sodium phosphate anhydrous monobasic i le 500 mL o le vai, ma fa'aopopo le 5 mL o le triethylamine, sosoo ai ma le 1.4 g o le sodium lauryl sulfate.Fetuuna'i ile phosphoric acid fa'afefeteina (10% w/w) ile pH ole 2.5, ma fa'asusu ile vai ile 600 mL.Faafefiloi lenei vaifofo ma le 400 mL o le methanol.
Fofo talafeagai fa'aoga: 0.2 mg/mL ole USP Tranexamic Acid RS ma le 0.002 mg/mL ole USP Tranexamic Acid Related Compound C RS ile vai
Fofo masani: 50 µg/mL o le USP Tranexamic Acid RS ile vai
Fa'ata'ita'iga fofo: 10 mg/mL o le Tranexamic Acid ile vai
Faiga fa'akomepiuta
(Va'ai Chromatography <621>, Faiga Fa'atonu.)
Auala: LC
Su'esu'e: UV 220 nm
Koluma: 4.6-mm × 25-cm;5-µm fa'apipi'i L1
Fuafuaga tafe: 1 mL/min
Tele tui: 20 µL
Taimi ta'avale: 3 taimi le taimi o le fa'atumauina o le tranexamic acid
Faiga talafeagai
Fa'ata'ita'iga: Fa'atonuga fa'aoga fofo
Mana'oga talafeagai
I'uga: NLT 2.0 i le va o le Tranexamic Acid ma le 0.002 mg/mL o le tranexamic acid e feso'ota'i fa'aputu C.
Iloiloga
Faʻataʻitaʻiga: Fofo masani ma Faʻataʻitaʻiga fofo
Fa'atusatusa le pasene o mea leaga ta'itasi i le vaega o le Tranexamic Acid na ave:
I'uga = (rU/rS) × (CS/CU) × (0.1F)
rU = tali maualuga mo le mama taʻitasi mai le faʻataʻitaʻiga fofo
rS = tali pito maualuga mo le tranexamic acid mai le vaifofo Tulaga
CS = fa'asalaina o le USP Tranexamic Acid RS i le vaifofo masani (µg/mL)
CU = fa'asalaina o le Tranexamic Acid i le fa'ata'ita'iga fofo (mg/mL)
F = fa'atatau tali tali (silasila i le Fuafuaga Le mama 1)
Tulaga taliaina
Fa'aleaga tagata ta'ito'atasi: Va'ai Fuafuaga Le mama 1.
Aofa'i le mama: NMT 0.2%
[Manatua-Ia le amanaia soo se tumutumu e itiiti ifo i le 0.025%.]
Fa'aleaga Laulau 1
Igoa Taimi Taofi Fa'atatau Fa'atatau Tali Tali Fa'atatau Fa'atalia, NMT (%)
Tranexamic acid related compound Aa 2.1 1 0.1
Tranexamic acid fa'afeso'ota'i fa'aoga Bb 1.5 1.2 0.2
Tranexamic acid e feso'ota'i fa'atasi Cc 1.1 0.005 0.1
Tranexamic Acid 1.0 1.0 —
Tranexamic acid e feso'ota'i fa'atasi Dd 1.3 0.006 0.1
ose trans,trans-4,4¢-(Iminodimethylene)di(cyclohexanecarboxylic)acid.
b cis-4-(Aminomethyl) cyclohexanecarboxylic acid.
c (RS)-4-(Aminomethyl) cyclohex-1-enecarbocylic acid.
d 4-Aminomethyl benzoic acid.
SU'E FA'AMANATU
• Ma'imau ile Fa'agogo <731>: Fa'agogo 1.00 g ile 105 ile vacuum mo le 2 h.E leiloa le NMT 0.5% o lona mamafa.
FAAOPOOPOGA
• Fa'auma ma Teuina: Fa'asaoina i totonu o atigipusa fufusi, ma teu i se vevela e le sili atu i le 30.
• USP Reference Standards <11>
USP Tranexamic Acid RS Kiliki e Va'ai Fa'atulagaga
USP Tranexamic Acid Related Compound C RS
(RS)-4-(Aminomethyl)cyclohex-1-enecarbocylic acid.
C8H13NO2 155
Fa'afefea ona Fa'atau?Fa'amolemole fa'afeso'ota'iDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Tausaga Aafiaga?E sili atu nai lo le 15 tausaga o le poto masani i le gaosiga ma le auina atu i fafo o le tele o tulaga maualuga o vailaʻau faʻapitoa poʻo vailaʻau lelei.
Maketi Autu?Faʻatau atu i maketi i totonu o le atunuʻu, Amerika i Matu, Europa, Initia, Korea, Iapani, Ausetalia, ma isi.
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Tulaga leleiFaamautinoaga?Fa'atonuga lelei faiga.O meafaigaluega faʻapitoa mo suʻesuʻega e aofia ai le NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Fa'ata'ita'iga?O le tele o oloa e maua ai faʻataʻitaʻiga e leai se totogi mo le iloiloga lelei, o tau o felauaiga e tatau ona totogi e tagata faʻatau.
Fale Su'etusi?Fa'afeiloa'i su'etusi falegaosimea.Fa'amolemole fai se taimi vave.
MOQ?Leai MOQ.Laititi oka e talia.
Taimi Tiliva? Afai o loʻo i totonu o faʻatauga, e tolu aso e faʻamaonia le tuʻuina atu.
Felauaiga?E ala ile Express (FedEx, DHL), ile Air, ile Sea.
Pepa?A maeʻa le faʻatau atu auaunaga: COA, MOA, ROS, MSDS, ma isi mea e mafai ona tuʻuina atu.
Tulaga Fa'apitoa?E mafai ona tu'uina atu au'aunaga tu'ufa'atasiga fa'apitoa e fetaui lelei ma au su'esu'ega mana'oga.
Tulaga Totogi?Proforma invoice o le a lafo muamua pe a maeʻa le faʻamaoniga o le poloaiga, faʻapipiʻi a matou faʻamatalaga faletupe.Totogi e le T / T (Telex Transfer), PayPal, Western Union, ma isi.
Fa'ailoga Mata'utia Xi - Itaita
Fa'ailoga Tulaga lamatia 36/37/38 - Fa'aitaita'i i mata, faiga manava ma le pa'u.
Fa'amatalaga Saogalemu
S26 - Pe a pa'i i mata, fufulu vave i le tele o vai ma saili fautuaga faafoma'i.
S36 - Fa'aofu ofu puipui talafeagai.
S37/39 - Fai totigilima talafeagai ma mata/mata puipui
WGK Siamani 2
RTECS GU8400000
HS Code 2922491100
Vasega o Tulaga Lamatia
Oona LD50 i isumu, isumu (mg/kg): 1500, 1200 iv (Melander)
Tranexamic Acid (CAS: 1197-18-8) o se mea faʻapipiʻi gaosia o le amino acid lysine.Tranexamic acid (e masani ona faʻatauina i le laulau e pei o Lysteda ma i le IV fomu e pei o Cyklokapron i le US ma Transamin, Transcam i Asia, ma Espercil. i Amerika i Saute) e masani ona faʻatonuina mo le tele o le toto.Tranexamic acid o se antifibrinolytic e fa'atauva ai le fa'agaoioia o le plasminogen i le plasmin, o se mole e nafa ma le fa'aleagaina o fibrin.O le fibrin o le faʻavae autu mo le faʻavaeina o le toto i le hemostasis. Tranexamic acid e tusa ma le 8 taimi le gaioiga antifibrinolytic o se analog matua, ε-aminocaproic acid.Na muamua pateni i le 1957 ma maua lona uluai faamaoniga a le US i le 1986. Tranexamic Acid Applicaiton Faʻaaogaina e pei o le paʻepaʻe cosmetics E faʻaaogaina lautele ile falemaʻi ile taotoga, vailaʻau i totonu, urology, obstetrics ma gynecology, ma isi e togafitia ai faʻamaʻi toto eseese ma toto le masani ai i le taimi o taotoga, ma isi. E manatu o se vailaʻau hemostatic, lea e masani ona faʻaaogaina mo le hemostasis pe a maeʻa taotoga tetele ma le failele.O le mea moni, o le hemostasis atonu o le mafuaaga aupito maualalo lea e faʻaopoopo ai le tele o toothpastes e faʻamoemoe e iai sona aafiaga.
Tranexamic Acid (CAS: 1197-18-8)
Ta'otoga fatu
E masani ona fa'aoga ile taotoga o le fatu, fa'atasi ma le aunoa ma le cardiopulmonary bypass.E suitulaga i le aprotinin.
Ma'i masina toto
Fa'aaogaina e fai ma togafiti muamua e le'i fa'ama'i fa'amasani o le fa'aletonu o le toto, ma le mamafa o le toto e feso'ota'i ma fibroids uterine.O se su'esu'ega talu ai nei na fa'aalia ai o tagata mama'i e togafitia i le tranexamic acid e sili atu ona atia'e le thrombosis ma necrosis io latou fibroid, ma e ono i'u ai i le tiga ma le fiva.
Aafiaga pa'epa'e
O suʻesuʻega faʻapitoa mo le tele o tausaga ua faʻamaonia ai o le tranexamic acid e mafai ona faʻafefeteina lelei ma vave, lea e fesoasoani e faʻaalia ai se paʻu paʻepaʻe atoatoa ma susulu.O le a'afiaga o le tranexamic acid e fa'ate'aina ai e tusa ma le 50 taimi i luga ole Vitamin C, ma le 10 taimi ile AHA.Ole tapula'a ole fa'aoga ole 2% -3%, ma ile cosmetics ole aofa'i ole 0.5%
1. Mautu lelei
Pe a faatusatusa i mea masani whitening, tranexamic acid e maualuga le mautu, acid ma alkali tetee, ma e le faigofie ona aafia i le siosiomaga vevela;Leai se puipuiga o le va'a, leai se fa'aleagaina o faiga fa'asalalau, leai se fa'aosofia.
2. O le faiga o le paʻu e faigofie ona faʻafefe
E fetaui lelei mo le faʻamalamalamaina o mea, paʻepaʻe ma paleni le paʻu atoa o le paʻu.I le faaopoopo atu i le faʻamalamalamaina o mea, o le tranexamic acid e mafai foʻi ona faʻaleleia atili le manino o le lanu atoa o le paʻu ma le paʻu o le paʻu o le lotoifale.
3. E mafai ona mou ese atu lanu uliuli, freckles samasama, fa'ailoga siama, ma isi
O lanu uliuli e mafua mai i le faaleagaina o le UV ma le matua o le paʻu ma isi mea.Clotting acid e mafai ona faʻalavelaveina le gaioiga o tyrosinase ma melanocytes, faʻaitiitia le gaosiga o le melanin mai le faavae o le epidermis, ma e iai foʻi le aʻafiaga o le aveesea o lanu mumu.
4. saogalemu maualuga
O le maualuga o le faʻatonuga i mea teuteu e 2% ~ 3%.
5. Whitening aafiaga
Tranexamic Acid e fetaui lelei i ituaiga uma o paʻu mo le aveeseina o le pigmentation, paʻepaʻe paʻepaʻe ma faʻaitiitia faʻailoga, e pei o: Pigmentation pe a uma le la;Papauliuli;Pa'u ma'ale'ale;Ga'u ma fula;Tausiga pe a maeʻa le laser, togafitiga faʻamalama faʻamalosi.
