Valsartan CAS 137862-53-4 Su'ega 98.0~102.0% API
Faumea Faumea Valsartan ma Fesoota'iga Fa'atatau:
Valsartan CAS: 137862-53-4
L-Valine Methyl Ester Hydrochloride (H-Val-OMe·HCl) CAS: 6306-52-1
Igoa Vailaau | Valsartan |
Synonyms | N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine |
Numera CAS | 137862-53-4 |
CAT Numera | RF-API32 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C24H29N5O3 |
Molecular Weight | 435.52 |
Lisi Lisi | 116.0~117.0 ℃ |
Maumau | Hygroscopic |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e po'o le Pa'epa'e Pa'epa'e;Le manogi, Hygroscopic |
Fa'ailoaga | Ole alaleo IR ole fa'ata'ita'iga e fetaui ile fusi ole alaleo masani |
Fa'ailoaga | O le taimi fa'atumauina o le tumutumu tele i le chromatogram o le sauniuniga su'ega e fetaui ma le sauniuniga masani, e pei ona maua i le Su'ega. |
Solubility | Solu i le Methanol ma le Ethanol, Fa'ase'e solu i le Ethylacetate, Solu teisi i le Dichloromethane, Le solu i le Vai |
Susū (KF) | ≤1.00% |
O'o'o (420mm) | ≤0.02% (λ=420nm, C=0.05g/ml, L=1cm) |
Toega i luga o le mumu | ≤0.10% |
Metala mamafa | ≤10ppm |
D-Valsartan | ≤1.00% (HPLC) |
Mea Fa'atatau (HPLC) | |
Butyryl-Valsartan | ≤0.20% |
Benzyl-Valsartan | ≤0.10% |
Nofofua Le iloa le mama | ≤0.10% |
Aofa'i Fa'aleaga | ≤0.30% (E le aofia ai D-Valsartan) |
Solvents totoe (GC) | |
Methanol | ≤3000ppm |
Ethyl Acetate | ≤5000ppm |
N,N-Dimethylformamide | ≤880ppm |
Toluene | ≤890ppm |
Mama / Suʻesuʻega Metotia | >99.0% (HPLC fa'atatau i luga ole vai, e leai se soli) |
Tulaga Su'ega | United States Pharmacopoeia (USP) |
Fa'aoga | Mea Fa'afoma'i Gaoioiga (API) |
Valsartan (CAS: 137862-53-4) Le Faʻagasologa o Galuega Faʻagasologa
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua ma le tuʻuina atu o Valsartan (CAS: 137862-53-4) faʻatasi ai ma le maualuga.Valsartan o se nonpeptide angiotensin II AT1 fa'afeagai tali, Antihypertensive, ei ai le gafatia mo le toto maualuga ma suʻesuʻega faʻaletonu fatu.
Valsartan's antihypertensive aafiaga e sili atu le malosi nai lo le enalapril ma e talafeagai mo le togafitia o le toto maualuga, maualalo i le feololo maualuga maualuga, aemaise lava le maualuga maualuga e mafua mai i le faaleagaina o fatu.E mafai ona matua fa'aitiitia ai le proteinuria mo tagata ma'i toto maualuga e maua i le ma'i suka po'o galuega masani o le ate, ma e mafai ona fa'ateleina ai le uric acid ma le sodium urinary e puipuia ai le fatuga'o.Valsartan e talafeagai foi mo le faʻaitiitia o le cardiovascular mortality mo tagata mamaʻi maualuga (tuuvale ventricular faaletonu poʻo le faaletonu) pe a uma ona oʻo i se fatu fatu.