2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5 Remdesivir Yepakati COVID-19
Mugadziri Wekutengesa Kwekutengesa Remdesivir uye Vanoenderana Vanopindirana vane Hunhu Hwepamusoro
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Chemical Name | 2,3,5-Tri-O-benzyl-D-ribonolactone |
Mashoko anoreva zvakafanana | 2,3,5-Tri-O-Benzyl-D-Ribono-1,4-Lactone;Remdesivir Yepakati |
Nhamba yeCAS | 55094-52-5 |
Nhamba yeCAT | RF-PI301 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram |
Molecular Formula | C26H26O5 |
Molecular Weight | 418.49 |
Melting Point | 54.0-55.0℃ |
Storage Condition | Room Temperature |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Yellowish kana White Solid |
Solubility | Soluble muCH2Cl2 uye Insoluble muH2O |
NMR uye MS | Zvinofanira Kuenderana |
Identification | IR uye TLC |
Unyoro | ≤1.0% |
Residue paIgnition | ≤0.50% |
Chero Kusachena Kwemunhu | ≤0.50% |
Heavy Metals | ≤50ppm |
HPLC (210nm) | ≥99.0% |
HPLC (ELSD) | ≥99.0% |
Test Standard | Enterprise Standard |
Usage | Yepakati yeRemdesivir (CAS 1809249-37-3) |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
2,3,5-Tri-O-benzyl-D-ribonolactone (CAS 55094-52-5) ndeye Remdesivir yepakati.Remdesivir (CAS 1809249-37-3) inova antiviral mushonga mukirasi ye nucleotide analogs, inoshandiswa mukurapa COVID-19.Remdesivir (GS-5734) inova antiviral nucleoside analogue iyo inhibit murine hepatitis virus (MHV) ine yakafanana EC50 seSARS-CoV uye MERS-CoV.Coronaviruses (CoVs) mavhairasi ane tsinga imwe chete yeRNA anotapurira huwandu hwakasiyana hwemhuka.Muvanhu, maCoV aizivikanwa seanowanzo konzera dzihwa uye mabayo kudzamara pakubuda kweacute acute respiratory syndrome (SARS-CoV) muna 2002 uye Middle East respiratory syndrome coronavirus (MERS-CoV) muna 2012 kubva ku zoonotic masosi.Remdesivir ndiyo monophosphoramidate prodrug yeC-adenosine nucleoside analogue GS-441524.Mukunonoka kwebundu reuropi (DBT) masero ane utachiona neMHV, GS-5734 yakavharira MHV zvakanyanya kudarika GS-441524, ine GS-5734 EC50 ye 0.03 M. muSARS-CoV- uye MERS-CoV-yakatapukirwa yepakutanga yemunhu airway epithelial cell (HAE) tsika.