4-Benzyl-2-Hydroxymorpholin-3-imwe CAS 287930-73-8 Kuchena > 99.0% (HPLC) Aprepitant Intermediate Factory
Kutungamira mugadziri uye mutengesi
Pakati peAprepitant (CAS: 170729-80-3)
4-Benzyl-2-Hydroxymorpholin-3-imwe CAS 287930-73-8
(R) -1- [3,5-Bis(trifluoromethyl)phenyl]ethanol CAS 127852-28-2
Please contact: alvin@ruifuchem.com
Chemical Name | 4-Benzyl-2-Hydroxymorpholin-3-imwe |
Mashoko anoreva zvakafanana | 4-Benzyl-2-Hydroxy-Morpholin-3-imwe;2-Hydroxy-4- (Phenylmethyl) -3-Morpholinone;Aprepitant Kusachena 48;Fosaprepitant Kusachena 23;Aprepitant Intermediate Ⅱ |
Nhamba yeCAS | 287930-73-8 |
Nhamba yeCAT | RF2660 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
Molecular Formula | C11H13NO3 |
Molecular Weight | 207.23 |
Melting Point | 134.0 kusvika 138.0 ℃ |
Boiling Point | 441.7±45.0℃ |
Density | 1.292±0.06 g/cm3 |
Solubility mumvura | DMSO (Zvishoma), Methanol (Zvishoma, Kupisa) |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Ichena kune Off-White Crystal Powder |
Kuchena / Analysis Method | >99.0% (HPLC) |
Melting Point | 134.0 kusvika 138.0 ℃ |
Mvura (naKarl Fischer) | <0.50% |
Residue paIgnition | <0.20% |
Zvose Zvisina Kuchena | <1.00% |
Proton NMR Spectrum | Inopindirana neChimiro |
Test Standard | Enterprise Standard |
Usage | Pakati peAprepitant (CAS: 170729-80-3) Antiemetic Drug |
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro
Kutenga sei?Please contact: sales@ruifuchem.com or alvin@ruifuchem.com
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Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Russia, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
4-Benzyl-2-Hydroxymorpholin-3-one (CAS: 287930-73-8), iri pakati peAprepitant (CAS: 170729-80-3), inoshandiswa semishonga inorwisa antiemetic.Aprepitant inonzi neurokinin-1 (NK-1) receptor antagonist uye ndeyevamiririri vekurapa kwekurutsa panguva yekemotherapy yekenza.Yakatanga kubudirira kugadzirwa neMerck Company (German).Muna Kurume 2003, iyo US Food and Drug Administration yakaibvumidza kuti ishandiswe mukurapa chemotherapy yekurutsa.Ichi chigadzirwa chine hukama hwepamusoro hwekusarudza kune vanhu nepo iine hukama hwakaderera kune serotonin, dopamine uye glucocorticoid receptor affinity.Aprepitant, kana yakabatanidzwa ne5-HT3 receptor inhibitors (yakadai se ondansetron hydrochloride) uye corticosteroid dexamethasone, inogona kuwedzera kuderedza cisplatin-induced acute uye (kana) kunonoka emesis.Kushandisa mushonga uyu chete kunogona kuva nemamwe maitiro ekudzivirira.