4-Benzyl-2-Hydroxymorpholin-3-imwe CAS 287930-73-8 Kuchena > 99.0% (HPLC) Aprepitant Intermediate Factory

Tsanangudzo Pfupi

Zita: 4-Benzyl-2-Hydroxymorpholin-3-one

CAS: 287930-73-8

Kuchena:> 99.0% (HPLC)

Chitarisiko: Chichena kune Off-White Crystal Powder

Pakati peAprepitant (CAS: 170729-80-3) Antiemetic

High Quality, Commercial Production

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E-Mail: alvin@ruifuchem.com


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Tsanangudzo:

Kutungamira mugadziri uye mutengesi
Pakati peAprepitant (CAS: 170729-80-3)
4-Benzyl-2-Hydroxymorpholin-3-imwe CAS 287930-73-8
(R) -1- [3,5-Bis(trifluoromethyl)phenyl]ethanol CAS 127852-28-2
Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name 4-Benzyl-2-Hydroxymorpholin-3-imwe
Mashoko anoreva zvakafanana 4-Benzyl-2-Hydroxy-Morpholin-3-imwe;2-Hydroxy-4- (Phenylmethyl) -3-Morpholinone;Aprepitant Kusachena 48;Fosaprepitant Kusachena 23;Aprepitant Intermediate Ⅱ
Nhamba yeCAS 287930-73-8
Nhamba yeCAT RF2660
Stock Status MuStock, Kugadzirwa Kunokwira Kusvika Matani
Molecular Formula C11H13NO3
Molecular Weight 207.23
Melting Point 134.0 kusvika 138.0 ℃
Boiling Point 441.7±45.0℃
Density 1.292±0.06 g/cm3
Solubility mumvura DMSO (Zvishoma), Methanol (Zvishoma, Kupisa)
Brand Ruifu Chemical

Zvinotsanangurwa:

Item Zvinotsanangurwa
Chitarisiko Ichena kune Off-White Crystal Powder
Kuchena / Analysis Method >99.0% (HPLC)
Melting Point 134.0 kusvika 138.0 ℃
Mvura (naKarl Fischer) <0.50%
Residue paIgnition <0.20%
Zvose Zvisina Kuchena <1.00%
Proton NMR Spectrum Inopindirana neChimiro
Test Standard Enterprise Standard
Usage Pakati peAprepitant (CAS: 170729-80-3) Antiemetic Drug

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro

Zvakanakira:

Yakakwana Capacity: Inokwana zvivakwa uye matekiniki

Professional Service: Imwe inomira kutenga sevhisi

OEM Package: Tsika pasuru uye label iripo

Fast Delivery: Kana iri mukati me stock, mazuva matatu ekutumira anovimbiswa

Yakagadzika Supply: Chengetedza zvine musoro stock

Tsigiro yehunyanzvi: Tekinoroji mhinduro iripo

Tsika Synthesis Service: Kubva pamagiramu kusvika makirogiramu

Hunhu Hwepamusoro: Yakagadzira yakakwana yemhando yekusimbisa system

FAQ:

Kutenga sei?Please contact: sales@ruifuchem.com or alvin@ruifuchem.com 

Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.

Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Russia, Korea, Japan, Australia, nezvimwe.

Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.

HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.

Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.

Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.

MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.

Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.

Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.

Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.

Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.

Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.

Application:

4-Benzyl-2-Hydroxymorpholin-3-one (CAS: 287930-73-8), iri pakati peAprepitant (CAS: 170729-80-3), inoshandiswa semishonga inorwisa antiemetic.Aprepitant inonzi neurokinin-1 (NK-1) receptor antagonist uye ndeyevamiririri vekurapa kwekurutsa panguva yekemotherapy yekenza.Yakatanga kubudirira kugadzirwa neMerck Company (German).Muna Kurume 2003, iyo US Food and Drug Administration yakaibvumidza kuti ishandiswe mukurapa chemotherapy yekurutsa.Ichi chigadzirwa chine hukama hwepamusoro hwekusarudza kune vanhu nepo iine hukama hwakaderera kune serotonin, dopamine uye glucocorticoid receptor affinity.Aprepitant, kana yakabatanidzwa ne5-HT3 receptor inhibitors (yakadai se ondansetron hydrochloride) uye corticosteroid dexamethasone, inogona kuwedzera kuderedza cisplatin-induced acute uye (kana) kunonoka emesis.Kushandisa mushonga uyu chete kunogona kuva nemamwe maitiro ekudzivirira.

Nyora meseji yako pano uye titumire kwatiri