4-Hydroxycoumarin CAS 1076-38-6 Kuchena > 99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira kugadzira 4-Hydroxycoumarin (CAS: 1076-38-6) ine mhando yepamusoro.Ruifu Chemical inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, madiki uye akawanda akawanda aripo.Tenga 4-Hydroxycoumarin,Please contact: alvin@ruifuchem.com
| Chemical Name | 4-Hydroxycoumarin |
| Mashoko anoreva zvakafanana | 4-Hydroxy-1-Benzopyran-2-imwe;4-Coumarinyl Doro;4-Coumarinol;4-Hydroxy-2H-Benzo[b]pyran-2-one;4-Hydroxy-2H-Chromen-2-imwe;4-Hydroxychromen-2-imwe;Benzotetronic Acid |
| Stock Status | In Stock, Commerce Manufactured |
| Nhamba yeCAS | 1076-38-6 |
| Molecular Formula | C9H6O3 |
| Molecular Weight | 162.14 g/mol |
| Melting Point | 213.0~217.0℃(lit.) |
| Density | 1.446 |
| Mvura Solubility | Insoluble muMvura |
| Solubility | Soluble muEthanol uye Dimethyl Formamide |
| Storage Temp. | Nzvimbo Inotonhorera & Yakaoma |
| COA & MSDS | Available |
| Category | Pharmaceutical Intermediates |
| Brand | Ruifu Chemical |
| Items | Kuongorora Maitiro | Results |
| Chitarisiko | Ichena kana Inenge Yakachena Crystalline Powder | Zvinoenderana |
| Melting Point | 213.0~217.0℃ | 213.6~214.7℃ |
| Kurasika paKuomesa | <0.50% | 0.32% |
| Residue paIgnition | <0.20% | 0.08% |
| Masimbi anorema (Pb) | ≤10ppm | <10ppm |
| Kusachena Kumwechete | <0.30% | Zvinoenderana |
| Kuchena / Analysis Method | >99.0% (HPLC) | 99.64% |
| Infrared Spectrum | Inopindirana neChimiro | Zvinoenderana |
| 1 H NMR Spectrum | Inopindirana neChimiro | Zvinoenderana |
| Mhedziso | Chigadzirwa chacho chakaedzwa uye chinoenderana nezvakapihwa | |
Package:Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumudziyo wakavharwa zvakasimba.Chengetedza muimba yekuchengetera inotonhorera, yakaoma uye ine mhepo yakanaka.Dzivirira kubva kuchiedza uye unyoro.Hazvienderane neakasimba oxidizing agents uye mabhesi akasimba.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.
4 Test nzira
4.1 Chitarisiko (kutarisa kwekuona)
4.2 Kurasikirwa nekuomeswa
4.3 Kutemerwa kwe4-Hydroxycoumarin zvemukati
4.3.1 Nzira yekusarudza
Iwo masampuli akanyungudutswa muchikamu chenhare uye akatemerwa nepamusoro pekuita liquid chromatography paC18 column nepeak area normalization nzira.
4.3.2 Reagent
a) Acetonitrile: chromatographic yakachena (inotengeswa kunze);
b) Mvura: Mvura yakasvibiswa kana yechipiri mvura yakasvibiswa.
4.3.3 Chiridzwa
a) High performance liquid chromatography;
b) UV-inogadziriswa wavelength spectrometer;
c) Koramu yekuongorora: C18 column;
d) Ultrasonic oscillators.
4.3.4 Chromatographic kushanda mamiriro
a) Nharembozha: acetonitrile: mvura: phosphoric acid = 700:300:1 (V/V/ V);
b) Kuyerera kwehuwandu: 1.0ml / min;
c) Column tembiricha: tembiricha yekamuri;
d) Kuonekwa wavelength: 254nm
e) Saizi yemuenzaniso: 20μL
4.3.5 Kugadzirira kwebvunzo mhinduro
Weresa sampuli 20mg (yakarurama kusvika 0.002g), isa mubhodhoro re 25ml volumetric, iputse ne mobile phase mu 4.2.4 a) kusvika pachiyero, izunze zvakanaka mu ultrasonic shaker kuti ishandiswe gare gare.
4.3.6 Kutsunga zvirimo
Pasi pemamiriro e4.3.4 pamusoro, mhinduro yekuedza ichagadziriswa mushure mokunge chiridzwa chacho chagadziriswa.
4.3.7 Kuverenga
Iyo peak area normalization nzira yakashandiswa kuverenga zvabuda.
4.3.8 Kutsauka kunobvumirwa
Kutsauka kwezviyero zviviri hakupfuuri 0.5%, uye iyo yakaverengerwa kukosha kukosha inotorwa semhedzisiro yebvunzo.
4.4 Kutsunga kwekunyungudika.
5 Mitemo Yekuongorora
5.1 Batch yega yega yezvigadzirwa ichayedzwa nedhipatimendi rekuongorora mhando zvinoenderana nezvinhu zviri muchiyero ichi usati wabuda mufekitori.
5.2 Kutemerwa kwemabhechi
Batch yezvigadzirwa zvinogadzirwa nehuwandu hwekudya (anenge 200kg).
5.3 Sampling
Mabhegi maviri (madhiramu) anosarudzwa zvisina tsarukano kubva pakurongedza kwebatch yega yega yezvigadzirwa.Mushure mekuenzanisa uye kusanganiswa zvakaenzana, ivo vakakamurwa kuva 50g nenzira yezvikamu zvina, izvo zvakakamurwa kuita zvikamu zviviri, imwe yacho inoshandiswa pakuongorora uye imwe inochengeterwa kutaurwa.
5.4 Sarudzo
Batch yega yega yezvigadzirwa ichayedzwa zvinoenderana nezvinodiwa zvakanyorwa muchiyero ichi.Kana chero chinhu chikatadza kuzadzisa zvinodiwa zvakataurwa muchiyero ichi, chinotenderwa kudzokorora nekaviri sampling.Kana pachine chinhu chimwe chinotadza kuzadzisa zvinodiwa zvakataurwa muchiyero ichi, batch yezvigadzirwa ichanzi haina kukodzera.
5.5 Arbitration
Mushandisi ane kodzero yekuita ongororo yekugamuchirwa mukati memazuva gumi nemashanu mushure mekugamuchira zvinhu zvinoenderana nezvinodiwa zvechiyero ichi.Kana paine kupokana kwemhando ipi neipi, mapato ese ari maviri anogona kutaurirana kuti agadzirise, kana kupa sangano rekupokana nemutemo rakabvumiranwa nemapato ese kuti rigadzirise maererano nezvinodiwa zvechiyero ichi.
6 Labels uye mavara
Aya anotevera mamakisi achanamirwa kune chigadzirwa pasuru:
a) Zita rechigadzirwa;
b) Nhamba yakajairika;
c) Huremu hweNet;
d) Zuva rekugadzira kana nhamba yebatch;
e) Zita nekero yefekitari;
f) Hupenyu hwesherufu.
Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
Risk Codes
R22 - Zvinokuvadza kana ikamedzwa
R36/37/38 - Kushungurudza maziso, kufema system uye ganda.
Tsanangudzo Yekuchengetedza
S26 - Kana wasangana nemaziso, simbura nekukasira nemvura yakawanda uye tsvaga mazano ekurapwa.
S36 - Pfeka zvipfeko zvinodzivirira zvakakodzera.
WGK Germany 3
RTECS DJ3100000
TSCA Hongu
HS Code 2932201000
Hazard Note Irritant
4-Hydroxycoumarin (CAS: 1076-38-6) inonzi hydroxycoumarin iyo inonzi coumarin umo hydrogen panzvimbo ye4 inotsiviwa neboka re hydroxy.Iyo conjugate asidhi ye4-hydroxycoumarin (1-).
4-Hydroxycoumarin chirimwa chinobva kune antioxidant, chinodzivirira kubva kune lipid peroxidation, pamwe chete neanogona inhibitor yeHIV-1 Integrase.4-Hydroxycoumarins ikirasi yakakosha zvikuru yemishonga ye biologically inoshanda iyo inoshandiswa zvakanyanya se anticoagulants-Warfarin uye Acenocoumarol.
4-Hydroxycoumarin, inobuda mucoumarin, ndeimwe yeanonyanya kuenderana heterocyclic scaffolds uye anowanzo shandiswa mukuumbwa kweakasiyana organic komisheni.4-Hydroxycoumarin ine zvese zviri zviviri electrophilic uye nucleophilic properties.4-Hydroxycoumarin derivatives inoshandiswa se anticoagulant, antibacterial, antifungal, antiviral, antitumor, antiprotozoal, insecticidal, antimycobacterial, antimutagenic, antioxidant, anti-inflammatory agents, HIV protease inhibitors uye tyrosine kinase inhibitors.
4-Hydroxycoumarin inobatanidzwa mune annulation reactions, nekuda kwehuwandu hwakawanda hwe acidity yeCH bond pa 3-position: matatu-component reaction ne isocyanides uye dialkyl acetylene dicarboxylates inopa annulated 4H-pyrans.
4-Hydroxycoumarin ndeyepakati pemushonga uye mishonga yezvipembenene.
4-Hydroxycoumarin zvakare inonhuwira, uye macoumarins akagoverwa zvakanyanya muumambo hwezvirimwa.
