5-(2-Fluorophenyl)-1H-Pyrrole-3-Carbaldehyde CAS 881674-56-2 Vonoprazan Fumarate Intermediate Purity ≥99.0%
Supply Vonoprazan Fumarate uye Related Intermediate
5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Chemical Name | 5-(2-Fluorophenyl)-1H-Pyrrole-3-Carbaldehyde |
| Mashoko anoreva zvakafanana | Vonoprazan Fumarate (TAK-438) Yepakati 3 |
| Nhamba yeCAS | 881674-56-2 |
| Nhamba yeCAT | RF-PI330 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
| Molecular Formula | C11H8FNO |
| Molecular Weight | 189.19 |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | Yero kusvika kuBrown Powder |
| Melting Point | 122.0~131.0℃ |
| Kuzivikanwa: RT(HPLC) | Gadzirisana neReference Standard |
| Kurasikirwa Pakuomesa | ≤0.50% |
| Residue On Ignition | ≤0.50% |
| Related Substances | |
| Kuchena | ≥99.0% |
| Chero Kusachena Kumwe | ≤0.50% |
| Zvose Zvisina Kuchena | ≤1.0% |
| Test Standard | Enterprise Standard |
| Usage | Pakati peVonoprazan Fumarate (TAK-438) (CAS 881681-01-2) |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
5-(2-Fluorophenyl) -1H-Pyrrole-3-Carbaldehyde (CAS 881674-56-2) inoshanda sereagent mukugadzirwa kwekugadzirwa kweinoveli pyrrole derivatives se potassium-competitive acid blocker (P-CAB).5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde ndiyo yepakati yeVonoprazan Fumarate (CAS 1260141-27-2).Vonoprazan fumarate (Takecab®), yakawanikwa uye yakagadziridzwa naTakeda naOtsuka, yakatenderwa nePMDA yekuJapan muna Zvita 2014, uye inoratidzwa mukurapa gastric ulcer, duodenal ulcer uye reflux esophagitis.Vonoprazan fumarate ine nzira itsva yekuita inonzi potassium-competitive acid blockers, iyo inodzivisa kusungwa kwe potassium ions kuH +, K + -ATPase (inozivikanwawo seproton pump) muchikamu chekupedzisira chegastric acid secretion mugastric parietal cells.Vonoprazan haidziviriri basa reNa +, K + -ATPase kunyange pazvikamu 500 nguva dzakakwirira kudarika iyo yeIC50 tsika dzavo pamusoro pegastric H +, K + -ATPase basa.Uyezve, mushonga wacho hauna kukanganiswa negastric secretory state, kusiyana nePPIs.
