5-Fluorocytosine (5-FC) CAS 2022-85-7 Kuchena ≥99.5% (HPLC) Capecitabine Emtricitabine Intermediate Factory

Tsanangudzo Pfupi

Zita reKemikari: 5-Fluorocytosine;5-FC

CAS: 2022-85-7

Kuonekwa: Ichena kana Inenge Yakachena Crystalline Powder

Kuchena: ≥99.5% (HPLC)

Pakati peCapecitabine (CAS: 154361-50-9) & Emtricitabine (CAS: 143491-57-0)

High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com


Product Detail

Related Products

Product Tags

Tsanangudzo:

Commerce Supply Capecitabine Related Intermediates:
5-Fluorocytosine CAS: 2022-85-7
2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine CAS: 161599-46-8
1,2,3-Tri-O-acetyl-5-deoxy-β-D-ribofuranose CAS: 62211-93-2
Capecitabine CAS: 154361-50-9 

Chemical Properties:

Zita 5-Fluorocytosine
Mashoko anoreva zvakafanana 5-FC;Flucytosine;4-Amino-5-fluoro-2-hydroxypyrimidine
Nhamba yeCAS 2022-85-7
Nhamba yeCAT RF-PI175
Stock Status MuStock, Kugadzirwa Kunokwira Kusvika Matani
Molecular Formula C4H4FN3O
Molecular Weight 129.09
Brand Ruifu Chemical

Zvinotsanangurwa:

Item Zvinotsanangurwa
Chitarisiko Ichena kana Inenge Yakachena Crystalline Powder
Kuzivikanwa IR Iyo infrared absorption spectrum yemuenzaniso inofanira kuenderana neyakajairwa spectrum
Kuchena / Analysis Method ≥99.5% (HPLC)
Cytosine ≤0.10%
Chero Kumwe Kusachena Kwemunhu ≤0.10%
Solubility Zvishoma Soluble mumvura;Zvishoma Soluble muDoro;Paractically muChloroform uye muEther
Kurasika paKuomesa ≤1.5% w/w (pa105℃ 4 h)
Residue paIgnition ≤0.10% w/w
Masimbi anorema (Pb) ≤20ppm
Fluonc ≤500ppm
5-Fluorouracil ≤0.10%
Assay 98.5% ~ 101.0% (yakaverengerwa pane yakaomeswa hwaro)
Test Standard Enterprise Standard
Usage Capecitabine & Emtricitabine Intermediate;Pharmaceutical Intermediates
Upstream Product Cytosine CAS: 71-30-7

5-Fluorocytosine (5-FC) CAS: 2022-85-7 Analysis Method
Kutaridzika-Muchena kana Kuda Kuda Kuchena Crystalline Powder
Kurasikirwa paKuomesa-Dry it pa105 kwemaawa mana: inorasikirwa kwete kupfuura 1.50% yehuremu hwayo.
Residue paIgnition-kwete kupfuura 0.1%.
Heavy Metals-kwete kupfuura 0.002%.
Fluoride-Sanganisa 70 mL yemushonga uchangobva kugadzirwa wakazara potassium chloride ine 30 mL ye isopropyl doro, zadza electrode neyakajeka supernatant, uye bvumira iyo electrode kuti irambe iri mumusanganiswa kweasingasviki maawa maviri isati yashandiswa, kana zviri nani usiku humwe.
Paunenge uchitora zviyero, endesa mhinduro kune 150-mL beaker, uye kunyudza magetsi.Isai bhaa rine polytef-yakavharidzirwa inobvongodza mubeaker, isa beaker pane magnetic stirrer ine insulated top, uye bvumira kubvongodza kusvika kuenzana kwawanikwa (inenge 1 kusvika maminitsi maviri).Shamba uye woomesa ma electrode pakati pezviyero, uchichenjerera kuti usakwenya kristaro mune chaiyo ion electrode.
Edza kugona kwegadziriro yega yega yega, uye ronga huwandu hwefluoride, mumg pa100 mL, maringe nezvinogoneka, mumV, papepa resemilogarithmic.Pima kugona kwegadziriro yeMuedzo, uye tarisa kubva payakajairwa curve iyo fluoride concentration, mumg pa100 mL.Verenga chikamu chefluoride muchikamu cheFlucytosine chakatorwa neformula:
C / 10
umo C ndiyo chiyero chefluoride, mu mg pa 100 mL, kubva kune yakajairwa curve: kwete kupfuura 0.05% yefluoride inowanikwa.
Fluorouracil-Dissolve 250 mg mu 10 mL yemusanganiswa weglacial acetic acid nemvura (4: 1).Isa 20 µL yemhinduro iyi kune yakatetepa-layer chromatographic plate yakaputirwa ne0.5-mm layer yemusanganiswa wesilica gel musanganiswa.Pandiro imwe chete isa 20 µL, mu10-µL increments, ye0.025 mg per mL mhinduro yeUSP Fluorouracil RS mumusanganiswa weglacial acetic acid nemvura (4: 1).Gadzira chromatogram mumusanganiswa wechloroform uye glacial acetic acid (13: 7) kusvikira iyo inonyungudutsa mberi yafamba kwete pasi pemasendimita gumi nemana kubva pamavambo.Bvisa ndiro kubva mukamuri iri kukura, uye bvumira iyo inonyungudutsa kuti ibude.Tsvaga mavara pandiro nekutarisa pasi penguva pfupi-wavelength UV radiation: chero nzvimbo kubva mumhinduro iri pasi pekuyedzwa haina kukura muhukuru uye kusimba pane iyo nzvimbo paRF inogadzirwa neiyo Standard solution, inoenderana neisingapfuure 0.1% ye fluorouracil.
Assay-Nzvimbo inenge 400 mg yeFlucytosine, yakanyatsoyera, mu 250-mL beaker, wedzera 150 mL yemusanganiswa we 2 mavhoriyamu eglacial acetic acid uye 1 vhoriyamu yeacetic anhydride, uye nyunguduka, ichidziya zvinyoro kana zvichidikanwa.Titrate potentiometrically ne 0.1 N perchloric acid VS, uchishandisa calomel-girazi electrode system.Ita chisungo chisina chinhu, uye ita chero gadziriso inodiwa.Imwe mL ye0.1 N perchloric acid yakaenzana ne12.91 mg yeC4H4FN3O.Flucytosine ine kwete pasi pe98,5 muzana uye kwete kupfuura 101.0 muzana yeC4H4FN3O, yakaverengerwa pane yakaomeswa.

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.

Zvakanakira:

1

FAQ:

Application:

Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri uye mutengesi we5-Fluorocytosine CAS: 2022-85-7 (Fluorocytosine; 5-FC) ine mhando yepamusoro, inoshandiswa zvakanyanya muorganic synthesis, synthesis yemishonga yepakati uye Active Pharmaceutical Ingredient. (API) synthesis.5-Fluorocytosine (CAS: 2022-85-7) ndiyo yepakati peCapecitabine (CAS: 154361-50-9) uye Emtricitabine (CAS: 143491-57-0).

5-Fluorocytosine inonzi fluorinated analog ye cytosine.5-FC inotenderwa neUS Chikafu neDrug Administration (FDA) senge antifungal mumiririri anoshandiswa kurapa Candida uye Cryptococcus.Nguva pfupi yadarika nekuvandudzwa kwejene therapy, 5-FC yakaunzwa seprodrug yakabatana neiyo cytosine deaminase kuzviuraya gene.

Nyora meseji yako pano ugotitumira