5-Methylisoxazole-4-Carboxylic Acid CAS 42831-50-5 Leflunomide Intermediate Purity >99.0% (HPLC)

Tsanangudzo Pfupi

Kemikari Zita: 5-Methylisoxazole-4-Carboxylic Acid

Synonyms: 5-Methyl-4-Isoxazolecarboxylic Acid

CAS: 42831-50-5

Kuchena:> 99.0% (HPLC)

Hupfu hwakachena kusvika kuYellow Crystalline, Husina hwema

Pakati peLeflunomide (CAS: 75706-12-6)

Bata: Dr. Alvin Huang

Nharembozha/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira kugadzira 5-Methylisoxazole-4-Carboxylic Acid (CAS: 42831-50-5) ine mhando yepamusoro.Ruifu inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, sevhisi yakanakisa, diki uye yakawanda yakawanda iripo.Tenga 5-Methylisoxazole-4-Carboxylic Acid,Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	5-Methylisoxazole-4-Carboxylic Acid
Mashoko anoreva zvakafanana	5-Methyl-4-Isoxazolecarboxylic Acid
Kusachena	Leflunomide EP Kusachena D/ Leflunomide BP Kusachena D
Stock Status	MuStock, Commerce Scale
Nhamba yeCAS	42831-50-5
Molecular Formula	C5H5NO3
Molecular Weight	127.10 g/mol
Melting Point	145.0 kusvika 149.0 ℃ (lit.)
Density	1.348±0.06 g/cm3
Storage Temp.	Nzvimbo Inotonhorera & Yakaoma (2~8℃)
COA & MSDS	Available
Brand	Ruifu Chemical

Zvinotsanangurwa:

Items	Kuongorora Maitiro	Results
Chitarisiko	Hupfu hwakachena kusvika kuYellow Crystalline, Husina hwema	Zvinoenderana
Melting Point	145.0 kusvika 149.0 ℃	147.8~148.5℃
Kurasika paKuomesa	≤0.50%	0.13%
Residue paIgnition	≤0.10%	0.04%
Masimbi anorema (Pb)	≤0.002%	<0.002%
3-Methyl Isomeric Compound	≤0.20%	<0.20%
Kuchena / Analysis Method	>99.0% (HPLC)	99.74%
Infrared Spectrum	Inopindirana neChimiro	Zvinoenderana
1 H NMR Spectrum	Inopindirana neChimiro	Zvinoenderana
Mhedziso	Chigadzirwa chacho chakaedzwa uye chinoenderana nezvakapihwa
Uses	Pharmaceutical Intermediate yeLeflunomide (CAS: 75706-12-6)

Pakeji/Kuchengeta/Shipping:

Package:Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumudziyo wakavharwa zvakasimba.Chengetedza munzvimbo inotonhorera, yakaoma (2 ~ 8 ℃) uye ine mhepo yakanaka yekuchengetera kure nezvinhu zvisingaenderane.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.

Zvakanakira:

Yakakwana Capacity: Inokwana zvivakwa uye matekiniki

Professional Service: Imwe inomira kutenga sevhisi

OEM Package: Tsika pasuru uye label iripo

Fast Delivery: Kana iri mukati me stock, mazuva matatu ekutumira anovimbiswa

Yakagadzika Supply: Chengetedza zvine musoro stock

Tsigiro yehunyanzvi: Tekinoroji mhinduro iripo

Tsika Synthesis Service: Kubva pamagiramu kusvika makirogiramu

Hunhu Hwepamusoro: Yakagadzira yakakwana yemhando yekusimbisa system

FAQ:

Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.

Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.

Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.

HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.

Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.

Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.

MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.

Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.

Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.

Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.

Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.

Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.

42831-50-5 - Njodzi uye Kuchengeteka:

Risk Codes
R36/37/38 - Kushungurudza maziso, kufema system uye ganda.
R37/38 - Inogumbura kune yekufema system uye ganda.
R36 - Kushungurudza maziso
R10 - Inopisa
Tsanangudzo Yekuchengetedza
S22 - Usafeme guruva.
S26 - Kana wasangana nemaziso, simbura nekukasira nemvura yakawanda uye tsvaga mazano ekurapwa.
S36/37/39 - Pfeka zvipfeko zvekudzivirira zvakakodzera, magurovhosi uye kudzivirira maziso/chiso.
S36 - Pfeka zvipfeko zvinodzivirira zvakakodzera.
S16 - Chengetedza kure nenzvimbo dzekudzima.
WGK Germany 3
HS Code 2917399090
Hazard Kirasi IRRITANT

Application:

5-Methylisoxazole-4-Carboxylic Acid (CAS: 42831-50-5) iri pakati pekugadzirwa kweLeflunomide (CAS: 75706-12-6).Leflunomide rudzi rwe isoxazole immunosuppressive mishonga ine anti-proliferative chiitiko, yemazuva ano pharmacology inoisa chigadzirwa ichi se antipyretic, analgesic uye anti-inflammatory drugs.Ichi chigadzirwa chinogona kukurumidza kushandurwa kune inoshanda metabolites uye inoita basa nechiropa uye intestinal cytoplasm uye microsomes, yayo;nzira huru iri panguva yeDNA synthesis, inhibiting yakakosha enzyme-DHODH (DHODH) basa, kuitira kuti nucleotides mukati meB lymphocyte ipere, inogumisa biosynthesis yeDNA neRNA, masero haakwanisi kupinda muchikamu, uye pakupedzisira haakwanisi. kupararira, zvichiita kuti anti-rheumatic effects, inokodzera kurapwa kwevanhu vakuru vane rheumatoid arthritis, ankylosing spondylitis, inogona kuderedza kuparadzwa kwemapfupa, kuderedza zviratidzo uye zviratidzo.Mukuwedzera, leflunomide inogonawo kudzivisa basa re tyrosine kinase, nokudaro richidzivisa kuwanda kweT cell, B cell uye masero asina kudzivirira, asi inogonawo, ne biosynthesis inhibition ye cyclooxygenase-2 (COX2), inhibit prostaglandin synthesis uye kushandisa anti- kuzvimba mhedzisiro uye inhibit mast masero uye basophils histamine kuburitswa.Kana chigadzirwa ichi chikashandiswa munhengo yekutapurirana varwere, kugadziridzwa kwedosi kwakaoma, kunonyanya kushandiswa kurapa rheumatoid arthritis uye zvimwe zvirwere zve autoimmune.