6-O-Methylguanine CAS 20535-83-5 Nelzarabine Intermediate Factory
Supply With High Purity, Commercial Production
Zita reKemikari: 6-O-Methylguanine
CAS: 20535-83-5
| Chemical Name | 6-O-Methylguanine |
| Mashoko anoreva zvakafanana | 2-Amino-6-Methoxypurine |
| Nhamba yeCAS | 20535-83-5 |
| Nhamba yeCAT | RF-PI509 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
| Molecular Formula | C6H7N5O |
| Molecular Weight | 165.16 |
| Melting Point | >300 ℃ (lit.) |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | Off-White Crystalline Powder |
| Assay / Analysis Method | ≥98.5% (HPLC) |
| Kurasika paKuomesa | ≤0.50% |
| Residue paIgnition | ≤0.50% |
| Zvose Zvisina Kuchena | ≤1.5% |
| Test Standard | Enterprise Standard |
| Usage | Pakati peNelzarabine (CAS: 121032-29-9), T-ALL & T-LBL |
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro.
6-O-Methylguanine (CAS: 20535-83-5) inogona kushandiswa sepakati mukati mekugadzirwa kweNelzarabine (CAS: 121032-29-9).Nelarabine is prodrug ye deoxyguanosine analogue-9-beta-D-arabinofuranosyl guanine (ara-G).Nelarabine demethylates mubasa readenosine deaminase (ADA) uye inoshanduka kuita ara-G.Nelarabine yakatanga kugadzirwa neGlaxoSmithKline.Musi waGumiguru 28, 2005 pasi pemvumo yeUS Food and Drug Administration, yakava mushonga mutsva wekurapa T-cell acute lymphoblastic leukemia (T-ALL) uye T-Cells lymphoblasticlymphoma (T-LBL) inoshingirira kana zvishoma. marudzi maviri echemotherapy regimens kana kudzoka zvakare mushure mekutanga kurapwa.Mushonga mutsva uyu wakanyorwa zviri pamutemo muUnited States muna 2006.
