7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2 Kuchena >99.0% (HPLC) Afatinib Dimaleate Intermediate Factory

Tsanangudzo Pfupi:

Zita: 7-Chloro-6-Nitro-4-Hydroxyquinazoline

CAS: 53449-14-2

Kuchena:> 99.0% (HPLC)

Chitarisiko: Chiedza Yero kusvika Chiedza Bhuruu Powder

Pakati peAfatinib Dimaleate (CAS: 850140-73-7)

E-Mail: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Ruifu Chemical Supply Intermediates yeAfatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-imwe CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS 314771-88-5

Chemical Properties:

Chemical Name	7-Chloro-6-Nitro-4-Hydroxyquinazoline
Mashoko anoreva zvakafanana	7-Chloro-4-Hydroxy-6-Nitroquinazoline;7-Chloro-6-Nitro-4-Quinazolinol;7-Chloro-6-Nitro-4-Quinazolinone;7-Chloro-6-Nitro-4(3H)-Quinazolinone;7-Chloro-6-Nitro-3,4-Dihydroquinazolin-4-imwe;7-Chloro-6-Nitroquinazolin-4(3H)-imwe
Nhamba yeCAS	53449-14-2
Nhamba yeCAT	RF-PI2030
Stock Status	MuStock, Kugadzirwa Kunokwira Kusvika Matani
Molecular Formula	C8H4ClN3O3
Molecular Weight	225.59
Sensitivity	Heat Sensitive
Solubility	Zvishoma Soluble muDimethylformamide
Brand	Ruifu Chemical

Zvinotsanangurwa:

Item	Zvinotsanangurwa
Chitarisiko	Yero Yero kusvika kuChiedza Brown Powder
Kuzivikanwa (HPLC)	Nguva Yekuchengeta Yemuenzaniso Inofanirwa Kuenderana neStandard
Kuchena / Analysis Method	>99.0% (HPLC)
Melting Point	300.0~303.0℃
Zvemumvura (KF)	<0.50%
Residue paIgnition	<0.30%
Kusachena 1	<0.50% (7-Chloro-4-Hydroxyquinazoline CAS: 31374-18-2)
Kusachena 2	<0.50% (5,7-Dichloro-4[1H]quinazolinone)
Kusachena 3	<1.00% (7-Chloro-8-Nitro-4[1H]quinazolinone)
Kumwe Kusachena Kumwechete	<0.20%
Zvose Zvisina Kuchena	<1.00%
Heavy Metals (as Pb)	<20ppm
Infrared Spectrum	Inopindirana neChimiro
Proton NMR Spectrum	Proton NMR Spectrum
Test Standard	Enterprise Standard
Usage	Pakati peAfatinib, Afatinib Dimaleate

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro

Zvakanakira:

FAQ:

Application:

7-Chloro-6-Nitro-4-Hydroxyquinazoline (CAS: 53449-14-2) iri pakati peAfatinib Dimaleate (CAS: 850140-73-7).Afatinib imhuri isingadzokerike ErbB yevavharidzi vanodzvanyirira kutapurirana ruzivo uye kuvhara nzira huru dzinosanganisirwa mukukura kwegomarara uye kupatsanura.Nekuti ErbB ruzivo rwemhuri yekufambisa nzira inogona kukonzereswa neakawanda mahomodimers uye heterodimers, panguva imwe chete inhibition yeakawanda ErbB nhengo dzemhuri (seEGFR, HER2, ErbB3 uye ErbB4) inogona kukanganisa zvinobudirira kudzika kweruzivo rwekudzika.Afatinib inoshandiswa kurapa imwe mhando yekenza yemapapu (isiri diki cell cell cancer cancer) yakapararira kune dzimwe nhengo dzemuviri.Iyo ndeyekirasi yemishonga inozivikanwa se kinase inhibitors.Inoshanda nekuderedza kana kumisa kukura kwekenza masero.Inosungira kune imwe puroteni (epidermal receptor-EGFR) mune mamwe mamota.