7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Yepakati Yakanyanya Kuchena
Manufacturer Supply Irinotecan uye Related Intermediates:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Yemahara Base CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
Chemical Name | 7-Ethyl-10-Hydroxycamptothecin |
Mashoko anoreva zvakafanana | SN-38 |
Nhamba yeCAS | 86639-52-3 |
Nhamba yeCAT | RF-PI242 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
Molecular Formula | C22H20N2O5 |
Molecular Weight | 392.41 |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Chiedza Yellowish White Crystals Powder |
Kuzivikanwa (IR, UV) | (1) Ultraviolet ray absorption spectrum zvinoenderana nezvinodiwa (2) Infrared ray absorption spectrum concordant ine referensi yakajairwa spectrum ichaenderana nemiedzo yakabvumidzwa. |
Melting Point | 228.0~235.0℃ |
Related Substances | ≤1.5% |
10-Hydroxycamptothecin | ≤0.30% |
7-Cthylcamptothecin | ≤0.70% |
Maximum Unknown Kusachena | ≤0.50% |
Kurasika paKuomesa | ≤1.0% |
Heavy Metals | ≤10ppm |
Residue paIgnition | ≤0.10% |
Kujeka Kwemhinduro | Pachena |
Assay | ≥98.0% (HPLC) |
Test Standard | Enterprise Standard |
Usage | Pharmaceutical Pakati peIrinotecan |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri uye mutengesi we7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) ine mhando yepamusoro.7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) inonzi metabolite inoshanda yeTopoisomerase I inhibitor Irinotecan.SN-38 (NK012) inhibits DNA uye RNA synthesis neIC50s ye0.077 uye 1.3 μM, zvichiteerana.7-Ethyl-10-Hydroxycamptothecin (SN-38), ndiyo inoshanda metabolite yeIrinotecan, semisynthetic inobva ku camptothecin, quinoline-based alkaloid inowanikwa mumakwati emuChinese camptotheca muti uye Asian nothapodytes muti.Kunyange zvazvo 7-Ethyl-10-Hydroxycamptothecin inosvika ka1,000 ine simba kupfuura Irinotecan, haisati yashandurwa kuita mumiriri wezvinodhaka ane simba nokuti hainyunguriki.Parizvino iri kuiswa kumiyedzo yekiriniki pamwe chete nezvimwe zvikamu izvo zvinogona kupedzisira zvabvumira kuti ishande seantineoplastic drug.