7-Fluoro-6-Nitroquinazolin-4(1H)-imwe CAS 162012-69-3 Kuchena>99.0% (HPLC) Afatinib Dimaleate Intermediate Factory

Tsanangudzo Pfupi:

Zita reKemikari: 7-Fluoro-6-Nitroquinazolin-4 (1H) -imwe

CAS: 162012-69-3

Kuchena:> 99.0% (HPLC)

Yero kusvika kuReddish Yero Crystal kana Powder

Pakati peAfatinib Dimaleate (CAS: 850140-73-7)

High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Ruifu Chemical Supply Intermediates yeAfatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-imwe CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS 314771-88-5

Chemical Properties:

Chemical Name	7-Fluoro-6-Nitroquinazolin-4(1H)-imwe
Mashoko anoreva zvakafanana	7-Fluoro-6-Nitroquinazolin-4(3H) -imwe;7-Fluoro-4-Hydroxy-6-Nitroquinazoline;7-Fluoro-6-Nitroquinazolin-4-ol;7-Fluoro-6-Nitro-4-Hydroxyquinazoline;7-Fluoro-6-Nitro-1H-Quinazolin-4-imwe
Nhamba yeCAS	162012-69-3
Nhamba yeCAT	RF-PI2025
Stock Status	MuStock, Kugadzirwa Kunokwira Kusvika Matani
Molecular Formula	C8H4FN3O3
Molecular Weight	209.13
Brand	Ruifu Chemical

Zvinotsanangurwa:

Item	Zvinotsanangurwa
Chitarisiko	Yero kusvika kuReddish Yero Crystal kana Powder
1 H NMR Spectrum	Zvinoenderana Nechimiro
Kuchena / Analysis Method	>99.0% (HPLC)
Kurasika paKuomesa	<0.50%
Zvose Zvisina Kuchena	<1.00%
Proton NMR Spectrum	Inopindirana neChimiro
Test Standard	Enterprise Standard
Usage	Pakati peAfatinib Dimaleate (CAS: 850140-73-7)

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro

Zvakanakira:

FAQ:

Application:

7-Fluoro-6-Nitroquinazolin-4 (1H)-imwe (CAS: 162012-69-3) iri pakati peAfatinib Dimaleate (CAS: 850140-73-7).Afatinib imhuri isingadzokerike ErbB yevavharidzi vanodzvanyirira kutapurirana ruzivo uye kuvhara nzira huru dzinosanganisirwa mukukura kwegomarara uye kupatsanura.Nekuti ErbB ruzivo rwemhuri yekufambisa nzira inogona kukonzereswa neakawanda mahomodimers uye heterodimers, panguva imwe chete inhibition yeakawanda ErbB nhengo dzemhuri (seEGFR, HER2, ErbB3 uye ErbB4) inogona kukanganisa zvinobudirira kudzika kweruzivo rwekudzika.Afatinib mushonga unobvumidzwa kurapa usiri diki cell lung carcinoma (NSCLC), wakagadzirwa naBoehringer Ingelheim.Inoshanda seangiokinase inhibitor.Kufanana nelapatinib uye neratinib, afatinib inonzi tyrosine kinase inhibitor (TKI) iyo inodzivisawo zvisingadzoreki inhibits epidermal growth factor receptor 2 (Her2) uye epidermal growth factor receptor (EGFR) kinases.Afatinib haisi kungoshanda chete kupesana neEGFR kuchinja kwakanangidzirwa nechizvarwa chekutanga TKIs likeerlotinib kana gefitinib, asiwo kune avo vasinganzwisisi maitiro aya ekurapa.Nekuda kwebasa rayo rekuwedzera kurwisa Her2, iri kuongororwa gomarara rezamu pamwe nemamwe EGFR uye Her2 inofambiswa negomarara.