S-Adenosyl-L-Methionine (Ademetionine; SAMe) CAS 29908-03-0
Ruifu Chemical ndiyo inotungamira kugadzira S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) ine mhando yepamusoro.Ruifu Chemical inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, sevhisi yakanakisa, idiki uye yakawanda huwandu huripo.Tenga S-Adenosyl-L-Methionine,Please contact: alvin@ruifuchem.com
| Chemical Name | S-Adenosyl-L-Methionine |
| Mashoko anoreva zvakafanana | Ademetionine;S-Adenosylmethionine;SAMe;SAM;AdoMet |
| Stock Status | MuStock, Commercial Production |
| Nhamba yeCAS | 29908-03-0 |
| Molecular Formula | C15H22N6O5S |
| Molecular Weight | 398.44 g/mol |
| Melting Point | 267.0~269.0℃ |
| Sensitive | Very Hygroscopic |
| Mvura Solubility | Soluble mumvura |
| Kunhuwa & Ravira | Hunhu |
| COA & MSDS | Available |
| Muenzaniso | Available |
| Origin | Shanghai, China |
| Brand | Ruifu Chemical |
| Items | Zvinotsanangurwa | Results |
| Chitarisiko | Inenge Yakachena Fine Powder (Yakanyanya Hygroscopic) | Yakasimbiswa |
| Solubility | Soluble mumvura | |
| Identification | 1. Chemical reaction | Positive reaction |
| 2. IR: Inopindirana nehuwandu hunowanikwa neRS | Yakasimbiswa | |
| 3. Nguva yekuchengetedza yepamusoro pepamusoro inosangana nezvikumbiro | Yakasimbiswa | |
| Acid Value | 1.5~2.5 | 1.9 |
| Kujeka uye Rudzi rweKugadzirisa | Haina Yakanyanya Ruvara Kupfuura RS Y1 | Yakasimbiswa |
| Mvura naKarl Fischer | ≤3.00% | 2.2% |
| Residue paIgnition | ≤0.30% | 0.14% |
| Masimbi anorema (Pb) | ≤10ppm | <10ppm |
| Endotoxin | ≤0.3EU/mg | Yakasimbiswa |
| Microbiological | Inofanira Kuita Zvinodiwa | |
| Total Plate Count | ≤1000cfu/g | 55cfu/g |
| Yeast & Mold | ≤100cfu/g | 12cfu/g |
| E. Coli | Asipo/10g | Zvinoenderana |
| S. Aureus | Asipo/10g | Zvinoenderana |
| Salmonella | Asipo/10g | Zvinoenderana |
| S-Adenosyl-L-Homocysteine | ≤0.50% | 0.10% |
| Methioadenosine | ≤1.00% | 0.24% |
| Adenine | ≤0.50% | 0.09% |
| Related Substances | ||
| Zvimwe Zvikuru Zvikuru | ≤0.20% | 0.01% |
| Zvimwe Zvisina Kuchena Zvakakwana | ≤0.50% | 0.006% |
| (S,S) Isomer | >62.0% | 79.4% |
| Butanedisulfonate | 46.0 ~ 49.0% (Base on Dried) | 47.5% |
| Ademetionine | 50.0 ~ 53.0% (Base on Dried) | 52.1% |
| Total Content | > 97.5% (Base on Dried) | 99.6% |
| Mhedziso | Chigadzirwa chakaedzwa uye chinoenderana nezvakapihwa | |
| Sherufu Hupenyu | 2 Makore Paakachengetedzwa Zvakanaka | |
Package:Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mudziyo wakavharwa zvakasimba uye chengeta muimba inotonhorera, yakaoma uye ine mhepo yakanaka kure nezvinhu zvisingaenderani.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.
Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
Risk Codes R49 - Inogona kukonzera gomarara nekufema
R23 - Muchetura nekufema
R34 - Zvinokonzera kupisa
Tsanangudzo Yekuchengetedza S53 - Dzivisa kubuda - wana mirairo yakakosha usati washandisa.
S23 - Usafeme mhute.
S36/37/39 - Pfeka zvipfeko zvekudzivirira zvakakodzera, magurovhosi uye kudzivirira maziso/chiso.
S45 - Kana pakaitika tsaona kana ukanzwa usinganzwe zvakanaka, tsvaga zano rekurapa nekukasira (ratidza chinyorwa pese pazvinogoneka.)
HS Code 2934999099
S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) inowanzobatanidza cosubstrate inobatanidzwa mukuendeswa kweboka remethyl.SAMe yakatanga kuwanikwa muItaly naGL Cantoni muna 1952, SAMe imorekuru rinogadzirwa nguva dzose nemasero mapenyu, rinogona kudzivirira kenza yechiropa, kukurudzira cartilaginous tishu kuumba uye concrescence, inogona kubatsira kurwisa kushushikana, chirwere cheAlzheimer, chirwere chechiropa, uye kurwadziwa osteoarthritis, SAMe yava kubvumwa pasi rose semishonga yakakosha yekurapa zvirwere zvechiropa.Mazuva ano SAMe inowanzoshandiswa mumishonga, indasitiri yechikafu chehutano pamusika wepamba uye wepasirese.SAMe inotengeswa muUnited States sechikafu chekuwedzera.
1. S-Adenosyl-L-Methionine chikafu chakanaka chechiropa, chinogona kudzivirira doro, zvinodhaka uye kukanganisa kwemasero echiropa;
2. S-Adenosyl-L-Methionine ine simba guru rekudzivirira pachirwere chisingaperi chine hepatitis uye zvimwe zvinokonzera kukanganisa kwechiropa, chirwere chemwoyo, kenza nezvimwe zvakadaro.
3. S-Adenosyl-L-Methionine yakawanikwa ichishanda semishonga yekurapa arthritis uye kuora mwoyo kukuru.
4. MuUnited States, SAM inotengeswa sechinhu chinovaka muviri pasi pezita rekutengesa SAM-e (zvakare yakapereterwa SAME kana SAMe).Zvimwe zvidzidzo zvakaratidza kuti kutora SAM nguva dzose kunogona kubatsira kurwisa kuora mwoyo, chirwere chechiropa, uye osteoarthritis kurwadziwa.Nhamba yemakiriniki miedzo yakaratidza kuti yakanaka pakuora mwoyo, zvimwe zvirwere zvechiropa uye osteoarthritis.Zvimwe zviratidzo zvose hazvina kusimbiswa.
5. Clinically inoshandiswa kuvandudza chiropa chinoshanda.Iko kusanganiswa neL-DOPA pakurapa chirwere cheParkinson kunogona kuvandudza kushanda kweL-dopa uye kuderedza mhedzisiro.Marwadzo emunharaunda, kunetseka kwechinguva uye kushaya hope panzvimbo yejekiseni inogona kuonekwa.
S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) inewo maitiro akanaka ekurapa paarthritis, fibrous muscle, migraine nezvimwe zvirwere, uye ine zvishoma zvishoma.Kare kuma1970s, SAMe yakashandiswa semushonga wekurapa arthritis muEurope.Muna 1999, iyo US FDA yakabvumidza SAMe sechigadzirwa chehutano uye yave imwe yezvinotengeswa zvinovaka muviri zvigadzirwa muUnited States.
S-Adenosyl-L-Methionine inonyanya kugadzirwa nemakemikari synthesis, kuvirisa uye enzymatic shanduko.Iyo nzira yekuvirisa ndeyekuwedzera iyo inotangira L-Methionine kune yekutanga svikiro ine C uye N masosi, uye yakawanda S-Adenosylmethionine inogona kuwanikwa nekugadzira hutachiona masero.Iyi parizvino ndiyo nzira huru yekugadzirwa kwemaindasitiri yeS-Adenosylmethionine.Pakati pavo, ma microorganisms anoshandiswa pakuvirisa anogona kuwanikwa nekuongorora kana kubatanidza nzira dzekuvaka, izvo zvakanyorwa muzvinyorwa zvakawanda uye patents kumba nekune dzimwe nyika.Zvimwe zvidzidzo zvakapa nzira yekugadzirira yeS-adenosylmethionine, vachishandisa polyhydroxy organic reagents kuchengetedza basa re enzyme, vachishandisa adenosine triphosphate precursor, L-Methionine uye phosphate ions se substrates, glucose kana / uye maltose sevanopa simba, kuwedzera kuumbwa. yesimbi ions, uye kushandisa permeable kugadzirwa dhizaini kukonzeresa kugadzirwa kweS-Adenosylmethionine mumasero akazara.Kushandisa kuumbwa kwesimbi ion kudzora kuyerera kwemetabolism kuvandudza simba rekuzvibatanidza, kuwedzera organic reagents kuchengetedza basa rebhakitiriya nema enzymes, uchishandisa permeable yekugadzira dhizaini kugadzirira S-Adenosylmethionine, kupfupisa iyo synthesis nguva, uye ita kuti chigadzirwa chiunganidze kunze kwesero, izvo zvinogona kuchengetedza mutengo wekuzoparadzana kunotevera uye kurerutsa matanho ekushanda.
Ruzivo rwekuchengetedzeka kwenguva refu kweS-Adenosyl-L-Methionine ishoma nekuti vatori vechikamu muzvidzidzo zvakawanda vakaitora kwenguva pfupi chete.Zvisinei, mune imwe yedzidzo yechirwere chechiropa chine doro, vatori vechikamu vakatora S-Adenosyl-L-methionine kwemakore maviri;muchidzidzo ichocho, hapana migumisiro yakakomba yakashumwa.
Vanhu vane bipolar disorder (chirwere chinoratidzwa nekushanduka-shanduka, kubva pakuora mwoyo kusvika ku mania) havafaniri kutora SAMe nokuda kwezviratidzo zvavo zvekuora mwoyo kunze kwekutungamirirwa kwehutano hwehutano nokuti SAMe inogona kuwedzera zviratidzo zve mania.
Kunyange zvazvo S-Adenosyl-L-Methionine yakashandiswa kurapa cholestasis panguva yekuzvitakura, kuchengetedzwa kwayo panguva yekuzvitakura hakuna kusimbiswa.
SAMe inogona kuderedza mhedzisiro yelevodopa (L-dopa), mushonga unoshandiswa kurapa chirwere cheParkinson.Zvinogonawo kuti SAMe inogona kuwirirana nemishonga uye zvokudya zvinowedzera mazinga e serotonin (kemikari inogadzirwa nemasero emagetsi), zvakadai semishonga inodzvinyirira, L-tryptophan, uye St. John's wort.
Pane kushushikana pamusoro pekushandiswa kweSAMe nevanhu vasina immunocompromised (seavo vane HIV).Immunocompromised vanhu vari panjodzi yePneumocystis carinii utachiona, uye SAMe inosimudzira kukura kweiyo microorganism.
Migumisiro yeSAMe haina kujairika, uye pazvinoitika kazhinji kacho matambudziko madiki akadai sekusvotwa kana kugaya kugaya.
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