Anastrozole CAS 120511-73-1 API Factory High Quality

Tsanangudzo Pfupi

Zita: Anastrozole

CAS: 120511-73-1

Chitarisiko: Ichena kusvika Kure-Ichena Crystalline Powder

Chiyero: 98.0% ~ 102.0%

AnastrozoleKurapa Gomarara Repazamu

API High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Mugadziri Wekutengesa ane Kuchena Kwepamusoro uye Hunhu Hwakagadzikana
Kemikari Zita: Anastrozole
CAS: 120511-73-1

Chemical Properties:

Zita	Anastrozole
Mashoko anoreva zvakafanana	Arimidex;α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl) -1,3-benzenediacetonitrile
Nhamba yeCAS	120511-73-1
Nhamba yeCAT	RF-API74
Stock Status	MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram
Molecular Formula	C17H19N5
Molecular Weight	293.37
Solubility	Soluble muDMSO uye Ethanol
Brand	Ruifu Chemical

Zvinotsanangurwa:

Item	Zvinotsanangurwa
Chitarisiko	Ichena kusvika kuOff-White Crystalline Powder
Identification A	IR/MS Inopindirana nereferensi chiyero
Kuzivikanwa B	HPLC uye peak chimiro: Inoenderana nereferensi
Melting Point	81.0~84.0℃
Mvura Yemukati (neKF)	≤0.30%
Residue paIgnition	≤0.10%
Kurasika paKuomesa	≤0.50%
Heavy Metals	≤10ppm
Related Substances
Kusachena A	≤0.10%
Kusachena B	≤0.20%
Kusachena C	≤0.20%
Kusachena D	≤0.10%
Kusachena E	≤0.10%
Single Other Kusachena	≤0.10%
Zvose Zvisina Kuchena	≤0.50%
Residual Solvents
Cyclohexane	≤0.30%
Ethyl Acetate	≤0.50%
Assay	98.0% ~ 102.0% (pane yakaomeswa)
Sherufu Hupenyu	24 Mwedzi
Test Standard	Enterprise Standard;United States Pharmacopoeia (USP) Standard
Usage	Kurapa Gomarara Repazamu

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.

Zvakanakira:

FAQ:

Application:

Anastrozole (CAS 120511-73-1), isiri-steroidal, yechitatu-chizvarwa achiral triazole derivative inotengeswa seARIMIDEX® neAstraZeneca Pharmaceuticals LP1.Icho chimwe chechitatu-chizvarwa aromatase inhibitor iyo inonyanya kukwikwidza uye inosarudza inhibitor ye aromatase, nokudaro ichivhara kutendeuka kwe testosterone mu estradiol uye androstenedione mu estrone.Kudzivirirwa kwearomatase enzyme kunoitika kunyanya kuburikidza nemakwikwi ekusunga kwearomatase kune hemegroup ye cytochrome P450, kuderera kweesrogen biosynthesis mumativi emuviri uye muzamu.

Anastrozole mushonga unowanzo bvumidzwa kurapa kenza yemazamu yekutanga.Kufanana nemamwe aromatase inhibitors, iyo inonyanya kukosha yakashata yaive njodzi yakawedzera yekutyoka kwemapfupa, iyo yeanastrozole yaingogumira panguva yekurapa.Iyo ine hunhu ine huturu hunyoro kana ichienzaniswa nechemotherapy;zvisinei, zvakaonekwa kuti varwere vakawanda vanorapwa neanastrozole vakanyunyuta pamusoro pezviratidzo zvekubatana pane zvaitarisirwa, kunyanya kuoma kwedhijitari kwakafanana neiyo yerheumatoid arthritis.Mimwe miedzo yekiriniki yeanastrozole yevakadzi mushure mekuenda kumwedzi vane kenza yemazamu muEurope uye United States yakashuma kusagadzikana kwemusculoskeletal sezviitiko zvakashata.Anastrozole (Arimidex®) is aromatase inhibitor yakatenderwa muEU, US uye kune dzimwe nyika pasi rese kuti ishandiswe seadjuvant kurapwa muvakadzi vepashure memenopausal vane danho rekutanga, hormone receptor-positive kenza yemazamu.Inotenderwa zvakare muEU nedzimwe nyika pasi rese kuti ienderere mberi nekurapa adjuvant muvakadzi vanga vatove nemakore 2-3 e-adjuvant tamoxifen kurapwa kwegomarara rezamu.