Argatroban CAS 74863-84-6 API Factory High Purity Anticoagulant
Manufacturer Supply Argatroban Related Intermediates:
Ethyl (2R,4R)-4-Methyl-2-Piperidinecarboxylate CAS 74892-82-3
N-Nitro-1,2,3,4-tetradehydro Argatroban Ethyl Ester CAS 74874-09-2
3-Methyl-8-Quinolinesulphonyl Chloride CAS 74863-82-4
Argatroban Monohydrate CAS 141396-28-3
Argatroban Anhydrous CAS 74863-84-6
| Chemical Name | Argatroban |
| Mashoko anoreva zvakafanana | Argatroban Anhydrous |
| Nhamba yeCAS | 74863-84-6 |
| Nhamba yeCAT | RF-API67 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram |
| Molecular Formula | C23H36N6O5S |
| Molecular Weight | 508.63 |
| Melting Point | 188.0~189.0℃ |
| Boiling Point | 801.3ºC pa760 mmHg |
| Density | 1.47 g/cm3 |
| Shipping Condition | Yakatumirwa Pasi peAmbient Temperature |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | Ichena kusvika kuOff-White Crystalline Powder |
| Kuzivikanwa HPLC | Iyo nguva yekuchengeta yemusimboti peak yakawanikwa kubva muyedzo mhinduro inoenderana neiyo yakawanikwa kubva kuStandard solution, sekuyedzwa muAssay. |
| Kuzivikanwa IR | Inofambirana neiyo IR Spectrum yeAG RS |
| Identification UV | Muiyo 259nm uye 332nm wavelength nzvimbo inofanirwa kunge iine yakanyanya kunyura. |
| Mvura | 2.5-4.5% |
| Solution Rudzi & Kujeka | Mhinduro Inofanira Kuve Yakajeka Mavara |
| Rondedzera Zvinhu | |
| Kusachena A + Kusachena H | ≤0.10% |
| Kusachena B | ≤0.10% |
| Kusachena C + Kusachena E | ≤0.10% |
| Kusachena D | ≤0.10% |
| Kusachena I | ≤0.10% |
| Bach yekusachena kusingazivikanwe | ≤0.10% |
| Zvose Zvisina Kuchena | ≤0.30% |
| Residual Solvents | |
| Methanol | ≤3000ppm |
| Ethanol | ≤5000ppm |
| Dichloromethane | ≤600ppm |
| Ethyl Acetate | ≤5000ppm |
| Enantiomer (HPLC) | ≤0.10% |
| Isomer Ratio (HPLC) | 30.0% -40.0% |
| Chloride | ≤0.01% |
| Residue paIgnition | ≤0.10% |
| Heavy Metals | ≤10ppm |
| Bacterial Endotoxins | <5EU/mg |
| Microbial Limit | TAMC ≤1000 cfu/g |
| Assay | 98.0% -102.0% (pane anhydrous basis) |
| Test Standard | Enterprise Standard |
| Usage | API, Synthetic Antithrombotic Agent Anticoagulant |
Package: Bhodhoro, Aluminium foil bag, Cardboard Drum, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri uye mutengesi weArgatroban (CAS: 74863-84-6) ine mhando yepamusoro, API.
Argatroban (CAS: 74863-84-6) is a new synthetic antithrombotic agent inobatsira mukuchengetedza anticoagulation ivo ischemic sitiroko uye kuparadzira intravascular coagulation.Iyo anticoagulant iyo idiki molecule yakananga thrombin inhibitor.Muna 2000, argatroban yakabvumirwa neFood and Drug Administration (FDA) yeprophylaxis kana kurapwa kwethrombosis kune varwere vane heparin-induced thrombocytopenia (HIT).Muna 2002, yakatenderwa kushandiswa panguva yepercutaneous coronary interventions kune varwere vane HIT kana vari panjodzi yekuigadzira.Muna 2012, yakatenderwa neMHRA kuUK kuti iite anticoagulation muvarwere vane heparin-induced thrombocytopenia Type II (HIT) vanoda parenteral antithrombotic therapy.
