Bicalutamide CAS 90357-06-5 API Fekitari Yepamusoro Yemhando Yepamusoro Prostate Kenza
Mugadziri Wekutengesa ane Kuchena Kwepamusoro uye Hunhu Hwakagadzikana
Zita: Bicalutamide
CAS: 90357-06-5
Bicalutamide mukurapa kweAdvanced Prostate Cancer
API High Quality, Commercial Production
Zita | Bicalutamide |
Mashoko anoreva zvakafanana | N- [4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropionamide |
Nhamba yeCAS | 90357-06-5 |
Nhamba yeCAT | RF-API76 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram |
Molecular Formula | C18H14F4N2O4S |
Molecular Weight | 430.37 |
Storage Temperature | 2-8℃ |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Ichena kusvika kuOff-White Crystalline Powder |
Identification A | IR: Spectrum yemuenzaniso inoenderana neiyo yereferenzi standard |
Kuzivikanwa B | HPLC: Nguva yekuchengetedza yepamusoro pepamusoro pemhinduro yemuenzaniso inoenderana neiyo yeyakajairwa mhinduro |
Chiziviso C | Organic Fluoride Identification |
Solubility | Yakasununguka Soluble muAcetone uye Tetrahydrofuran, Zvishoma Soluble muEthyl Acetate |
Melting Point | 191.0 ~ 195.0℃ |
Mvura Yemukati (neKF) | ≤0.20% |
Fluoride Content | 15.9% ~ 18.5% |
Kurasika paKuomesa | ≤0.50% |
Residue paIgnition | ≤0.10% |
Heavy Metals | ≤10ppm |
Residual Solvents | |
Tetrahydrofuran | ≤0.072% |
Toluene | ≤0.089% |
N-Hexane | ≤0.029% |
Acetone | ≤0.50% |
Ethyl Acetate | ≤0.50% |
Related Substances | |
N,N'-Dimethyl Acetamide | ≤0.109% |
Bicalutamide Aminobenzonitrile | ≤0.10% |
Bicalutamide Inoenderana Musanganiswa A Isomer A | ≤0.10% |
Bicalutamide Inoenderana Musanganiswa A Isomer B | ≤0.10% |
Desfluoro Bicalutamide | ≤0.20% |
2-Fluoro Bicalutamide | ≤0.20% |
Deoxy Bicalutamide | ≤0.20% |
Bicalutamide sulfide | ≤0.10% |
Chero Kusachena Kusina Kutaurwa | ≤0.10% |
Zvose Zvisina Kuchena | ≤0.50% |
Particle Size | 90% <10um;50% <5um |
Assay | 98.0% ~ 102.0% (pane yakaomeswa) |
Miedzo yeMicrobiological | |
Total Viable Aerobic Count | ≤500CFU/g |
Mbiriso uye Molds | ≤50CFU/g |
Sherufu Hupenyu | 24 Mwedzi |
Test Standard | Enterprise Standard;USP Standard |
Usage | API, mukurapwa kweAdvanced Prostate Cancer |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Bicalutamide (CAS: 90357-06-5) isiri-steroidal androgen antagonist, iyo inokwikwidza androgen receptor ne androgen, inovhara masero ekutorwa kwe androgen, uye inhibits kusungwa kwe androgens kune iyo inotarisirwa nhengo.Inosunga ne androgen receptor iyo inoumba receptor complex, iyo inopinda mukati uye yakabatanidzwa ne nucleoprotein, nokudaro inhibiting tumor cell kukura.Inogona kuve semushonga wekutanga-palliative kurapwa kwepamusoro prostate cancer.Bicalutamide yakavambwa kuUnited Kingdom, musika wayo wekutanga pasi rose, wekurapwa kwegomarara reprostate rakasanganiswa neanalogi yeLHRH kana kuvhiya.A non-steroidal, peripherally selective antiandrogen, bicalutamide inhibisa chiito che dihydrotestosterone uye testosterone panzvimbo dzakanangwa nemakwikwi kusunga kune cytosolic androgen receptor.Yakanzi yakatenderwa zvakanaka pasina yakakosha yemwoyo uye metabolic side effects nekuda kwekubatsirwa kwekushayikwa chero steroid chiitiko.Kushanda kwebicalutamide se monotherapy kwakaratidzwa nekiriniki.Nhamba dzekupindura dzinovimbisa dzakataurwawo mukurapa colorectal, zamu, pancreas uye dzisiri diki cell cancer cancer.