Biotin CAS 58-85-5 Assay 97.5 ~ 100.5% Fekitari
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira kugadzira Biotin (Vitamin H) (CAS: 58-85-5) ine mhando yepamusoro.Ruifu Chemical inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, sevhisi yakanakisa, idiki uye yakawanda huwandu huripo.Tenga Biotin (CAS: 58-85-5),Please contact: alvin@ruifuchem.com
| Chemical Name | Biotin |
| Mashoko anoreva zvakafanana | D-Biotin;D(+)-Biotin;Vitamin H;Bios II;vhitamini B7;Coenzyme R;Biotinum |
| Stock Status | MuStock, Commercial Production |
| Nhamba yeCAS | 58-85-5 |
| Molecular Formula | C10H16N2O3S |
| Molecular Weight | 244.31 g/mol |
| Melting Point | 231.0~233.0℃(lit.) |
| Mvura Solubility | Zvishoma Soluble mumvura |
| Solubility mu 0.1mol/L NaOH | Kuda Kujeka |
| Solubility | Zvishoma Soluble muDoro, Chloroform, Ether |
| COA & MSDS | Available |
| Origin | Shanghai, China |
| Brand | Ruifu Chemical |
| Items | Zvinotsanangurwa | Results |
| Chitarisiko | Ichena kana Inenge Yakachena Crystalline Powder | White Crystalline Powder |
| Identification | IR Mechi neReference IR Spectrum | Zvinoenderana |
| Nguva Yekuchengeta | Inofanira kufanana neiyo yeRS | Zvinoenderana |
| Kutenderera kwakananga [a]20/D | +89.0° kusvika +93.0° (C=2 mu 0.1 M NaOH) | +90.8° |
| Assay | 97.5~100.5% | 99.8% |
| Kurasika paKuomesa | <0.50% | 0.05% |
| Related Substances | ||
| Kusachena Kwemunhu | <1.00% | Zvinoenderana |
| Zvose Zvisina Kuchena | <2.00% | Zvinoenderana |
| Residual Solvents | ||
| Benzene | <2ppm | <0.2ppm |
| Toluene | <100ppm | <10ppm |
| DMSO | <5000ppm | <500ppm |
| Microbial Test | ||
| Total Viable Aerobic Count | ≤1000cfu/g | Zvinoenderana |
| Yeasts uye Molds Count | ≤100cfu/g | Zvinoenderana |
| Escherichia Coli | ND/1g | / |
| Staphylococcus Aureus | ND/1g | / |
| Pseudomonas Aeruginosa | ND/1g | / |
| Enterobacteria | ND/1g | / |
| Salmonella Mhando | ND/10g | / |
| Mhedziso | Chigadzirwa chakaedzwa uye chinoenderana nezvakapihwa | |
Package:Fluorinated Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mudziyo wakavharwa zvakasimba uye chengeta munzvimbo inotonhorera, yakaoma (2~8℃) uye inofefeterwa nemhepo yakanaka kure nezvinhu zvisingaenderane.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.
TSANANGURO Ongororo Biotin ine NLT 97.5% uye NMT 100.5% yeBiotin (C10H16N2O3S).
KUZIVA
• A. INFRARED ABSORPTION <197K>
B. Inosangana nezvinodiwa muSpecific Tests for Optical Rotation, Specific Rotation <781S>.
C. Nguva yekuchengeta yenhongonya huru yeSample solution inoenderana neiyo yeStandard solution, sezvakawanikwa muAssay.
ASSAY
• MAITIRO
Mushonga webuffer: Dissolve 1 g ye sodium perchlorate monohydrate mu 500 mL yemvura, wedzera 1 mL ye phosphoric acid, uye nyorovesa nemvura kusvika pa1000 mL.
Nharembozha chikamu: Acetonitrile uye Buffer mhinduro (8.5: 91.5)
Diluent: Acetonitrile nemvura (1:4)
Mushonga wakajairika: 0.1 mg/mL yeUSP Biotin RS muDiluent.Sonicate kana zvichidiwa kunyungudutsa
Sample solution: 0.1 mg/mL yeBiotin muDiluent.Sonicate kana zvichidiwa kunyungudutsa.
Chromatographic system
(Ona Chromatography <621>, System Suitability.)
Modhi: LC
Detector: UV 200 nm
Column: 4.6-mm × 15-cm;3-µm kurongedza L7
Kuyerera kweyero: 1.2 mL/min
Jekiseni saizi: 50 µL
Kukodzera kwehurongwa
Muenzaniso: Standard solution
Kukodzera zvinodiwa
Muswe chinhu: NMT 1.5
Relative standard kutsauswa: NMT 2.0% yemajekiseni akadzokorora
Analysis
Samples: Yakajairwa mhinduro uye Sample mhinduro
Verenga chikamu cheBiotin (C10H16N2O3S) muchikamu cheBiotin chakatorwa:
Mhedzisiro = (rU/rS) × (CS/CU) × 100
rU = peak mhinduro kubva kuSample solution
rS = mhinduro yepamusoro kubva kune Standard solution
CS = kuunganidzwa kweUSP Biotin RS muiyo Standard solution (mg/mL)
CU = kusangana kweBiotin muSample solution (mg/mL)
Maitiro ekugamuchira: 97.5% -100.5%
KUSIRIRA
• RELAM COMPOUNDS
Buffer solution, Mobile phase, Diluent, Standard solution, Sample solution, Chromatographic system uye System suitability: Enderera mberi sekurairwa muAssay.
Analysis
Muenzaniso: Sample solution
Edza mhinduro dzepamusoro dzeSample solution.
Verengai muzana yekusachena kwega kwega muchikamu cheBiotin chakatorwa:
Mhedzisiro = (rU/rT) × 100
rU = peak mhinduro yekusachena yega yega kubva kuSample solution
rT = uwandu hwemhinduro dzepamusoro-soro dzepamusoro pese kubva mumhinduro yeSample
Maitiro ekugamuchira
Kusachena kwemunhu: NMT 1.0%
Yese tsvina: NMT 2.0%
ZVIYEDZO ZVAKANAKA
• OPTICAL kutenderera, Chaiyo Rotation <781S>
Sample solution: 20 mg/mL mu 0.1 N sodium hydroxide
Maitiro ekugamuchira: +89 ° kusvika +93 °
ZVIMWE ZVINODIWA
• KUPAKIRA UYE KUCHENGESHA: Chengetedza mumagaba akaomarara.
• USP REFERENCE ZVINHU <11>
USP Biotin RS
Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
Hazard Symbols Xn - Zvinokuvadza
Risk Codes R20/21/22 - Zvinokuvadza nekufema, kubata neganda uye kana ikamedzwa.
R36/37/38 - Kushungurudza maziso, kufema system uye ganda.
Tsanangudzo Yekuchengetedza S24/25 - Dzivisa kusangana neganda nemeso.
S36 - Pfeka zvipfeko zvinodzivirira zvakakodzera.
S26 - Kana wasangana nemaziso, simbura nekukasira nemvura yakawanda uye tsvaga mazano ekurapwa.
WGK Germany 1
RTECS XJ9088200
FLUKA BRAND F CODES 8
TSCA Hongu
HS Code 2936290000
Toxicity LD50 nemuromo muTsuro:> 2000 mg/kg
Biotin (Vitamin H; Vitamin B7) (CAS: 58-85-5)
Biotin ivhitamini inonyungudika mumvura mumhando sere, biotin.Iyo coenzyme - kana mubatsiri enzyme - inoshandiswa mune akawanda metabolic maitiro mumuviri.Dchemicalbook-biotin inobatanidzwa mu lipid uye protein metabolism, inobatsira kushandura zvokudya kuva glucose, iyo muviri unogona kushandisa sesimba.Izvo zvakakoshawo pakuchengetedza ganda, bvudzi uye mucous membranes.
Sekuwedzera kwekudya, Biotin inonyanya kushandiswa kune huku uye kudya kwembesa.Kazhinji premixed mass fraction ndeye 1% -2%.
Biotin inovaka muviri.Zvinoenderana neChina GB2760-90 mirau, inogona kushandiswa seindasitiri yechikafu seyamuro yekugadzirisa.Iine physiological mabasa ekudzivirira zvirwere zveganda uye kukurudzira lipid metabolism nezvimwe zvakadaro.
Biotin is carboxylase coenzyme, inobatanidzwa mune akawanda carboxylation reactions, uye yakakosha coenzyme mumetabolism yeshuga, mapuroteni uye mafuta.
Biotin inoshandiswa sechikafu chinosimbisa.Biotin inoshandiswa pakudya kwevacheche nehuwandu hwe 0.1 ~ 0.4mg / kg, mumvura yekunwa 0.02 ~ 0.08mg / kg.
Biotin inogona kushandiswa kunyora mapuroteni, maantigen, masoja ekudzivirira chirwere, nucleic acids (DNA, RNA) zvichingodaro.
Biotin inogona kuita kuti vhudzi riwedzere, kudzivirira kurasikirwa kwebvudzi rekutanga uye kuvandudza kuramba kwechisikigo kweganda.Izvo zvakare zvine humwe hunyanzvi hwekurwisa kuunyana.Inogona kukwidziridza hurongwa hwese hweganda, kuwedzera kuchinjika kwezvipikiri, kuvandudza chimiro che brittle zvipikiri uye kuita kuti zvipikiri zvive zvakanaka uye zvakapfava nekusimudzira synthesis ye lipids.
Kusavapo kwebiotin kunogona kukonzera dermatitis, atrophic glossitis, hyperesthesia, myalgia, malaise, anorexia, uye kuderera kwekushaya ropa, uye zviratidzo zvinopera ne biotin supplementation.Iyo inonyanya kukonzeresa mhedzisiro ndeye kubuda kwe cystic acne.Asi kune vanhu vazhinji, kunyangwe kunyanyisa kunwa kwevhitamini iyi hakukonzeri kukanganisa kwakashata.Zvisinei, vakadzi vane pamuviri havafaniri kutora biotin nekuda kwengozi yekubvisa pamuviri.
Kuchetura kweBiotin kunoratidzika kunge kwakaderera, kurapwa kweseborrheic dermatitis ine madosi akakwira eBiotin hakuna kuratidza kusakwana kweprotein metabolism kana zvikanganiso zvemajini uye kumwe kukanganiswa kwemetabolism.Kuedza kwemhuka kwakaratidzawo kuchetura kweBiotin.
