Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8 Purity ≥99.5% (HPLC) Sitagliptin Phosphate Monohydrate Yepakati
Supply Sitagliptin Phosphate Monohydrate Related Intermediates:
Sitagliptin API CAS 486460-32-6
Purogiramu inonzi Sitagliptin Phosphate Monohydrate CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Yepakati CAS 486460-21-3
Chemical Name | Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid |
Mashoko anoreva zvakafanana | (R)-Sitagliptin N-Boc-Acid Kusachena |
Nhamba yeCAS | 486460-00-8 |
Nhamba yeCAT | RF-PI1192 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
Molecular Formula | C15H18F3NO4 |
Molecular Weight | 333.31 |
Melting Point | 136.0~138.0℃ |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Ichena kusvika kuOff-White Powder |
Kuzivikanwa neHPLC | Nguva Yekuchengeta yeSample inowirirana neReference Standard |
Kurasika paKuomesa | ≤0.50% |
Sulfated Ash | ≤0.50% |
Heavy Metals | <20ppm |
Isomer | ≤0.50% |
Related Substances | |
Kusachena A | ≤0.50% |
Chero Kumwe Kusachena Kumwechete | ≤0.50% |
Zvose Zvisina Kuchena | ≤0.50% |
Kuchena | ≥99.5% (HPLC) |
Test Standard | Enterprise Standard |
Usage | Yepakati yeSitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro.
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid (CAS: 486460-00-8) inokosha yepakati yekugadzirira sitagliptin.Sitagliptinphosphate ndiyo yekutanga dipeptidase -IV(DPP-4) inhibitor yakagamuchirwa neFDA muna 2006. Inoshandiswa pakurapa kwechirwere cheshuga mellitus.Iyo ine pachena hypoglycemic mhedzisiro kana yakashandiswa yega kana musanganiswa ne metformin uye pioglitazone, uye yakachengeteka kutora, inotenderwa zvakanaka, ine mashoma maitiro akaipa.Muna Nyamavhuvhu 2009, mushonga uyu wakabvumidzwa neEuropean Union semushonga wekutanga wekurapa chirwere cheshuga cherudzi rwechipiri.Mushure megore ra2011, imwe neimwe nyika dzakabvumidza musanganiswa wesitagliptin phosphate uye alpha glycosidase inhibitors kana insulin.Sitagliptin phosphate ndiyo yekutanga FDA-yakatenderwa dipeptidyl peptidase-IV inhibitor kuti ishandiswe mukurapa rudzi rwechipiri chirwere cheshuga kusvika kure, pasi pezita rekutengesa reJanuvia.