Brigatinib CAS 1197953-54-0 Kuchena > 99.0% (HPLC)

Tsanangudzo Pfupi

Zita reKemikari: Brigatinib

Anoreva zvakafanana: AP-26113

CAS: 1197953-54-0

Kuchena:> 99.0% (HPLC)

Chitarisiko: Muchena kusvika Kuchena-Upfu

Bata: Dr. Alvin Huang

Nharembozha/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

1197953-54-0 -Tsanangudzo:

Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri weBrigatinib (AP-26113) (CAS: 1197953-54-0) ine mhando yepamusoro.Ruifu Chemical inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, sevhisi yakanakisa, idiki uye yakawanda huwandu huripo.Tenga Brigatinib,Please contact: alvin@ruifuchem.com

1197953-54-0 -Chemical Properties:

Chemical Name	Brigatinib
Mashoko anoreva zvakafanana	AP26113;AP-26113;5-Chloro-N4-[2-(Dimethylphosphinyl)phenyl]-N2-[2-Methoxy-4-[4-(4-Methyl-1-Piperazinyl)-1-Piperidinyl]phenyl]-2,4-Pyrimidinediamine
Stock Status	MuStock, Commercial Production
Nhamba yeCAS	1197953-54-0
Molecular Formula	C29H39ClN7O2P
Molecular Weight	584.09 g/mol
Melting Point	>203 ℃(Zvita)
Density	1.31±0.10 g/cm3
COA & MSDS	Available
Origin	Shanghai, China
Brand	Ruifu Chemical

1197953-54-0 -Zvinotsanangurwa:

Items	Zvinotsanangurwa	Results
Chitarisiko	Ichena kusvika kuOff-White Powder	Zvinoenderana
Kuchena / Analysis Method	>99.0% (HPLC)	99.26%
Max.Kusachena Kumwechete	<1.00%	0.25%
Kurasika paKuomesa	<1.00%	0.27%
Infrared Spectrum	Zvinoenderana NeChimiro	Zvinoenderana
1H NMR Spectrum	Zvinoenderana NeChimiro	Zvinoenderana
Mhedziso	Chigadzirwa chakaedzwa uye chinoenderana nezvakapihwa

Pakeji/Kuchengeta/Shipping:

Package:Fluorinated Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mudziyo wakavharwa zvakasimba uye chengeta muimba inotonhorera, yakaoma uye ine mhepo yakanaka kure nezvinhu zvisingaenderani.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.

Zvakanakira:

Yakakwana Capacity: Inokwana zvivakwa uye matekiniki

Professional Service: Imwe inomira kutenga sevhisi

OEM Package: Tsika pasuru uye label iripo

Fast Delivery: Kana iri mukati me stock, mazuva matatu ekutumira anovimbiswa

Yakagadzika Supply: Chengetedza zvine musoro stock

Tsigiro yehunyanzvi: Tekinoroji mhinduro iripo

Tsika Synthesis Service: Kubva pamagiramu kusvika makirogiramu

Hunhu Hwepamusoro: Yakagadzira yakakwana yemhando yekusimbisa system

FAQ:

Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.

Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.

Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.

HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.

Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.

Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.

MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.

Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.

Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.

Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.

Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.

Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.

1197953-54-0 - Tsanangudzo Yese:

Brigatinib (AP-26113) (CAS: 1197953-54-0) inoferefeta diki-morekuru rakanangana nekurapa cancer irikudziridzwa neARIAD Pharmaceuticals, Inc. Brigatinib mushonga unoshandiswa kurapa cancer inodzvanya epidermal growth factor receptor (EGFR) uye anaplastic lymphoma kinase (ALK).Brigatinib inosarudza agonist inopesana nekusiyana kweEGFR kusiyana nemhando dzomusango.Mushonga uyu unoratidzawo kusarudzika kunopesana neiyo ALK-EML4 fusion gene, inova chinhu chakakosha pakugadziriswa kweanogona kubatwa nemapapu parenchyma.Brigatinib inonyorerwa varwere vane majini chaiwo asina kujairika uye kana isiri-diki cell kenza yemapapu (NSCLC) isinga pindure kune manejimendi nemimwe mishonga.Brigatinib inorongedzerwa sekinase inhibitor, iyo maitiro ekuita anosanganisira kudzvanyirira kuita kwemapuroteni asina kujairika anowedzera kuwanda kwekenza maseru.

1197953-54-0 - Zviratidzo:

Brigatinib (CAS: 1197953-54-0) inonyorerwa varwere vane mafomu chaiwo eNSCLC akapararira kune zvikamu zvakasiyana-siyana zvemuviri muvanhu vakamborapwa nemimwe mishonga yekenza yakadai seCrizotinib, uye mamiriro avo akawedzera kuipa. kana kuti dzinoratidza zviratidzo zvishoma zvekuvandudzwa.Iri kunyanya pasi pekuferefetwa kwekurapa kwayo pane isiri-diki cell kenza yemapapu (NSCLC) uko ALK inoshandiswa uye kuchinja kweEGFP kunowanzoitika.

1197953-54-0 - Application:

Brigatinib (AP-26113) (CAS: 1197953-54-0) inhibitor yechizvarwa chitsva che tyrosine kinase, inoratidza kushanda kwakakosha muALK+ metastatic NSCLC.Musi waNyamavhuvhu 30, 2016, United States FDA yakapa bugtinib senzira yekurapa uye isingawanzo mushonga weALK+NSCLC mune varwere vakagadzira kana vasingakwanisi kushivirira Crizotinib, chizvarwa chekutanga ALK+NSCLC kurapwa.Ipa iyo yekutanga kunyorwa kwechikumbiro chekuongorora uye bvumidza iyo data rekunyorera kuti riunzwe pane inotenderera.Iyo FDA yakabvumidza Bugtinib muna Kubvumbi 28, 2017, pasi pezita rekutengesa Alunbrigtm.