Candesartan Cilexetil CAS 145040-37-5 Kuchena > 99.0% (HPLC) API Factory

Tsanangudzo Pfupi

Zita reKemikari: Candesartan Cilexetil

CAS: 145040-37-5

Kuchena:> 99.0% (HPLC)

Chitarisiko: Ichena kusvika Kure-Ichena Crystalline Powder

A Selective Angiotensin II Receptor Antagonist

API High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Tsanangudzo:

Ruifu Chemical Supply Candesartan Cilexetil Yepakati Nekuchena Kwakanyanya
Candesartan Cilexetil CAS 145040-37-5
Candesartan CAS 139481-59-7
1-Chloroethyl Cyclohexyl Carbonate CAS 99464-83-2
Candesartan Cilexetil Yepakati Eethyl Ester C6 CAS 139481-41-7
Candesartan Cilexetil Yepakati CAS 139481-44-0
Trityl Candesartan Cilexetil CAS 170791-09-0

Chemical Properties:

Chemical Name	Candesartan Cilexetil
Mashoko anoreva zvakafanana	TCV-116;1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H -benzo[d]imidazole-7-Carboxylate
Nhamba yeCAS	145040-37-5
Nhamba yeCAT	RF-PI1891
Stock Status	MuStock, Kugadzirwa Kunokwira Kusvika Matani
Molecular Formula	C33H34N6O6
Molecular Weight	610.66
Brand	Ruifu Chemical

Zvinotsanangurwa:

Item	Zvinotsanangurwa
Chitarisiko	Ichena kusvika kuOff-White Crystalline Powder
Kuzivikanwa HPLC	Nguva yekuchengeta yenhongonya huru muchromatogram yemuenzaniso inoenderana neiyo iri muchromatogram yakawanikwa nechiyero.
Kuzivikanwa IR	IR infrared absorption spectrum yakafanana neiyo yeCandesartan Cilexetil reference standard.
Kujeka uye Rudzi Solution	Mhinduro mu chloroform pa5% yakajeka uye isina ruvara
Kuchena / Analysis Method	>99.0% (HPLC)
Melting Point	155.0 ~ 160.0 ℃
Kurasika paKuomesa	<0.30%
Residue paIgnition	<0.10%
Heavy Metals	<10ppm
Arsenic (As)	<1ppm
Particle Size Distribution	90% <30 μm
Organic Kusachena	kubudikidza HPLC
Ethyl Candesartan	<0.15%
Desethyl Candesartan	<0.15%
N2-Ethyl Candesartan Cilexei	<0.15%
Chero Kusachena Kusingazivikanwe	<0.15%
Zvose Zvisina Kuchena	<0.60%
Kuongororwa nePotentiometry	99.0 ~ 101.0% yeC33H34N6O6, yakaverengerwa pane anhydrous substance
Organic Volatile Kusachena
Methano	<0.30%
Ethanol	<0.50%
Diethyl Ether	<0.50%
Aceton	<0.50%
Dichloromethan	<0.06%
Dimethylformamide	<0.088%
Microbiological Contarnination
Total Aerobic Microbial Count	<1000cfu/g
Molds & Yeasts	<100cfu/g
E.Coli	Absent
Salmonella	Absent
Test Standard	Enterprise Standard
Usage	API;Antihypertensive Agent

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro

Zvakanakira:

FAQ:

Application:

Candesartan Cilexetil (TCV-116) (CAS: 145040-37-5) inonzi angiotensin II receptor antagonist ine IC50 ye0.26 nM, inoshandiswa mukurapa kweBP.Candesartan inonzi angiotensin-receptor blocker (ARB) inogona kushandiswa yoga kana nemamwe maagent kurapa hypertension.Iyo inopihwa nemuromo senge prodrug, candesartan cilexetil, iyo inokurumidza kushandurwa kuita yayo inoshanda metabolite, candesartan, panguva yekutorwa mudumbu remukati.Candesartan inoderedza BP nekupikisa renin-angiotensin-aldosterone system (RAAS);inokwikwidza neangiotensin II yekusunga kune rudzi-1 angiotensin II receptor (AT1) subtype uye inodzivirira kuwedzera kweropa kuwedzera kweangiotensin II.Kusiyana neangiotensin-inoshandura enzyme (ACE) inhibitors, maARB haana mhedzisiro yekuoma kukosora.Candesartan inogona kushandiswa kurapa hypertension, isolated systolic hypertension, left ventricular hypertrophy uye chirwere cheshuga nephropathy.Inogonawo kushandiswa seimwe nzira yekurapa kwemoyo kukundikana, systolic dysfunction, myocardial infarction uye coronary artery chirwere.