Capecitabine CAS 154361-50-9 Kuchena 98.0%~102.0% API High Quality
Commerce Supply Capecitabine Related Intermediates:
5-Fluorocytosine CAS: 2022-85-7
2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine CAS: 161599-46-8
1,2,3-Tri-O-acetyl-5-deoxy-β-D-ribofuranose CAS: 62211-93-2
Capecitabine CAS: 154361-50-9
Chemical Name | Capecitabine |
Nhamba yeCAS | 154361-50-9 |
Nhamba yeCAT | RF-API08 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
Molecular Formula | C15H22FN3O6 |
Molecular Weight | 359.35 |
Melting Point | 110.0~121.0℃ |
Shipping Condition | Under Ambient Temperature |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | White Powder |
Identification | IR Spectrum sampuli inofanirwa kuenderana neyakasiyana yereferensi chiyero |
Identification | HPLC: Iyo nguva yekuchengeta yepamusoro yepamusoro yemuenzaniso mhinduro inofanirwa kuenderana neiyo yereferenzi standard. |
Kuchena | 98.0% ~ 102.0% (pane anhydrous uye solvent-isina hwaro) |
Optical Rotation | +96.0°~+100° |
Kunyorova (KF) | ≤0.30% |
Residue pamoto | ≤0.10% |
Heavy Metals | ≤20ppm |
Kusachena kwakabatana A | ≤0.30% |
Kusachena kwakabatana B | ≤0.30% |
Kusachena kwakabatana C | ≤0.10% (2',3'-Di O-Acety-5'-deoxy-5-Fluoroytidine) |
Kusachena Kusina Kutaurwa | ≤0.10% |
Zvose Zvisina Kutaurwa Netsvina | ≤0.50% |
Zvose Zvisina Kuchena | ≤1.5% |
Residual Solvents (GC) | |
Methanol | ≤3000ppm |
Ethanol | ≤5000ppm |
Dichloromethane | ≤600ppm |
Ethyl Acetate | ≤5000ppm |
Toluene | ≤800ppm |
Pyridine | ≤200ppm |
Hexane | ≤290ppm |
Total Aerobic Microbial Count | ≤200cfc/g |
Mbiriso uye Molds Count | ≤50cfc/g |
Test Standard | United States Pharmacopoeia (USP) |
Usage | Metastatic Breast Cancer |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Capecitabine (CAS: 154361-50-9) imhando itsva ye oral fluorinated pyrimidine drug.Capecitabine yakagadzirwa neRoche Pharmaceuticals, uye zita rayo rekutengesa rinonzi Xeloda.Capecitabine inogona kuchinja mu vivo kuita 5- FU, anti-metabolizim fluorine pyrimidine deoxynucleoside carbamate mushonga unonangana nekenza maseru kuvharisa kupatsanurwa kwesero uye kukanganisa RNA neprotein synthesis.Migumisiro yaro yakasungirirwa zvakanyanya kuzinga re TP enzyme kutaura mune neoplastic tissue uye kuDPD enzyme mu vivo kutaura.Inokodzera sekuwedzera kurapwa kwevakuru vepamusoro kana metastatic cancer yemazamu varwere vasina kupindura paclitaxel kana anthracycline mishonga inorwisa mabhakitiriya.Semushonga unorwisa cancer, unonyanya kushandiswa kurapa kenza yepamusoro kana metastatic yemazamu, pamwe nekurapa isiri-diki kenza yemapapu, kenza yepancreatic, dundira, rectal cancer, colon cancer, gastric cancer, uye mamwe mamota akasimba. .