Captopril CAS 62571-86-2 API Factory USP High Quality Anti-Hypertension
Mugadziri Wekutengesa ane Kuchena Kwepamusoro uye Hunhu Hwakagadzikana
Zita reKemikari: Captopril
CAS: 62571-86-2
Active Angiotensin-inoshandura Enzyme (ACE) Inhibitor Anti-Hypertension
API High Quality, Commercial Production
| Chemical Name | Captopril |
| Mashoko anoreva zvakafanana | (S)-(-)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline;(S)-(-)-1-(3-Mercapto-2-methylpropionyl)-L-proline |
| Nhamba yeCAS | 62571-86-2 |
| Nhamba yeCAT | RF-API89 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram |
| Molecular Formula | C9H15NO3S |
| Molecular Weight | 217.29 |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | Ichena kusvika kuOff-White Crystalline Powder |
| Assay | 98.0% ~ 102.0% (payakaomeswa) |
| Melting Point | 104.0~110.0℃ |
| Specific Optical Rotation | -125.0° kusvika -134.0° |
| Acidity | 7.0~8.0 |
| Kurasika paKuomesa | ≤1.0% |
| Residue paIgnition | ≤0.10% |
| Heavy Metals | ≤20ppm |
| Related Substances | |
| Captopril Disulfide | ≤1.0% |
| Single Unknown Kusachena | ≤0.20% |
| Zvose Zvisina Kuchena | ≤0.50% |
| Organic Volatile Impurities | Zvinoita Zvinodiwa |
| Test Standard | Enterprise Standard |
| Usage | Inoshandiswa seAnti-Hypertension Medicament |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Captopril ndiyo inonyanya kudzidzwa yeangiotensin-inoshandura enzyme (ACE) inhibitors inokurudzirwa semushonga weantihypertensive.Inovhara angiotensin-inoshandura enzyme, inodzvinyirira kuumbwa kweangiotensin II uye inobvisa vasoconstricting yayo pamidziyo ye arterial uye venous.Kwose vascular peripheral tension inoderedzwa, izvo zvinoguma nekudzikira kwearterial pressure.Captopril, pamwe chete nemamwe ACE inhibitors, inoratidzwa mukurapa kweBP, congestive heart failure, left ventricular dysfunction mushure memyocardial infarction, uye diabetes nephropathy.Mukurapa kwakakosha hypertension, captopril inoonekwa seyekutanga kurapa, ingave yega kana musanganiswa nethiazide diuretic.Kudzikira kweBP kunonyanya kukonzereswa nekudzikira kwese kwese peripheral resistance kana after load.Chakanakira kusanganisa captopril kurapa neyakajairwa thiazide diuretic ndechekuti iyo thiazide-induced hypokalemia inodzikiswa pamberi peACE inhibition, sezvo paine kuderera kwakanyanya kwekuburitswa kweangiotensin II-induced aldosterone.
