Daclatasvir Dihydrochloride Yepakati CAS 1007882-23-6 Kuchena > 98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri weDaclatasvir Dihydrochloride Intermediate (CAS: 1007882-23-6) ine mhando yepamusoro.Ruifu Chemical inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, madiki uye akawanda akawanda aripo.Tenga Daclatasvir Dihydrochloride Intermediates,Please contact: alvin@ruifuchem.com
| Chemical Name | Di-tert-Butyl (2S,2'S)-2,2'-(4,4'-Biphenyldiylbis(1H-imidazole-5,2-diyl))di(1-Pyrrolidinecarboxylate) |
| Mashoko anoreva zvakafanana | Daclatasvir Intermediate Ⅱ;Dacaltasvir Pakati 02;Daclatasvir T-Butyl Ester;Bis(2-Methyl-2-Propanyl) (2S,2'S) -2,2'-[4,4'-Biphenyldiylbis(1H-Imidazole-4,2-diyl)]di(1-Pyrrolidinecarboxylate);Di-tert-butyl 2,2′-([1,1′-Biphenyl]-4,4′-diylbis(1H-Imidazole-5,2-diyl))(2S,2'S)-bis(Pyridineidine-1- Carboxylate);(2S,2'S)-2,2'-([1,1'-Biphenyl]-4,4'-diyldi-1H-Imidazole-5,2-diyl) bis-1-Pyrrolidinecarboxylic Acid 1,1'-Bis (1,1-Dimethylethyl) Ester;Daclatasvir Kusachena 4 |
| Stock Status | MuStock, Commercial Production |
| Nhamba yeCAS | 1007882-23-6 |
| Molecular Formula | C40H51ClN8O6 |
| Molecular Weight | 775.35 g/mol |
| Boiling Point | 890.2±65.0℃ pa760 mmHg |
| Density | 1.220±0.06 g/cm3 |
| COA & MSDS | Available |
| Origin | Shanghai, China |
| Category | Pakati peDaclatasvir Dihydrochloride (CAS: 1009119-65-6) |
| Brand | Ruifu Chemical |
| Items | Zvinotsanangurwa | Results |
| Chitarisiko | Yero Yero kusvika Yero Hupfu | Light Yellow Powder |
| Kurasika paKuomesa | <1.00% | 0.65% |
| Maximum Single Kusachena | <1.00% | 0.45% |
| Zvose Zvisina Kuchena | <2.00% | 1.24% |
| Kuchena / Analysis Method | >98.0% (HPLC) | 98.76% |
| Infrared Spectrum | Zvinoenderana NeChimiro | Zvinoenderana |
| 1H NMR Spectrum | Zvinoenderana NeChimiro | Zvinoenderana |
| Mhedziso | Chigadzirwa chakaedzwa uye chinoenderana nezvakapihwa | |
| Application | Pakati peDaclatasvir Dihydrochloride (CAS: 1009119-65-6) | |
Package:Fluorinated Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mudziyo wakavharwa zvakasimba uye chengeta muimba inotonhorera, yakaoma uye ine mhepo yakanaka kure nezvinhu zvisingaenderani.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.
Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
Di-tert-Butyl (2S,2'S)-2,2'-(4,4'-Biphenyldiylbis(1H-imidazole-5,2-diyl))di(1-Pyrrolidinecarboxylate) (CAS: 1007882-23-6) iri pakati peDaclatasvir Dihydrochloride (CAS: 1009119-65-6).
Daclatasvir (Daklinza) yakawana "priority review", yakabatanidzwa neSorafenib yekurapa genotype III varwere vakuru vane chirwere chisingaperi chehepatitis C. Daklinza chave chiri mushonga wekutanga wakaratidzwa kuti unoshanda mukurapa genotype III hepatitis C virus. utachiona pasina kubatanidzwa pamwe interferon kana ribavirin.Interferon neRibavirin mishonga miviri inotenderwa neFDA pakurapa hutachiona hwehepatitis C.Hepatitis C chirwere chevhairasi chinogona kukonzera kuzvimba kwechiropa, zvichikonzera kudzikira kwekushanda kwechiropa kana kusashanda kwechiropa.Varwere vazhinji vane hepatitis C havana zviratidzo kusvikira kukuvara kwechiropa kwava pachena, izvo zvinogona kutora makore akati wandei.Pasi rose, genotype III hepatitis C ndiyo yechipiri inonyanya kuzivikanwa genotype yehepatitis C mushure meiyo genotype 1 hepatitis C uye inoonekwa seimwe yeanonyanya kuramba genotype zvirwere.Daklinza ipan-genotype NS5A replication complex inhibitor, ine simba rekudzivisa replication yeRNA uye gungano rehutachiona, huviri hwehutachiona hwehutachiona.Kune in vitro zvidzidzo, Daklinza yakaratidzwa kuva ne-anti-viral effect kurwisa genotype 1 ~ 6 hepatitis C virus.Daklinza inoperekedzwa neyambiro yekuti kusanganiswa kweamiodarone, Daklinza uye Sofosbuvir kunogona kukonzera kuderera kwakanyanya kwemoyo.Daklinza ipiritsi remuromo rine muyero wakakurudzirwa we60 mg kwe1 nguva / d, pamwe chete neSofosbuvir kwemavhiki gumi nemaviri.
Kambani yekutsvagisa nekusimudzira: Bristol-Myers Squibb.
Patent Literature: WO 2008021927A2 (Nyamavhuvhu 9, 2007).
Nguva yekushambadzira: Chikunguru 24, 2015 yakanyorwa muUnited States, zita rekutengesa Daklinza.
Zvinoratidza: Inoshandiswa pamwe chete Sofosbuvir pakurapa genotype 3 chisingaperi hepatitis C (HCV) utachiona.
Nzira yekuita: HCV nonstructural protein 5A (NS5A) inhibitors.Maitiro asina kunaka: kutemwa nemusoro uye kuneta.
Kugadzira uye zvirevo: Mahwendefa, 30 uye 60mg.
