CAS 177036-94-1 Kuchena >99.0% (HPLC) API Factory High Purity

Tsanangudzo Pfupi

CAS: 177036-94-1

Kuchena:> 99.0% (HPLC)

Chitarisiko: White kana Off-White Powder

Kurapa kwePulmonary Arterial Hypertension (PAH)

API High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Commercial Supply (CAS: 177036-94-1) Vanopindirana:
CAS: 177036-94-1
Methyl 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoate CAS: 178306-47-3
2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoic Acid CAS: 178306-51-9
(S)-2-Hydroxy-3-Methoxy-3,3-Diphenylpropionic Acid CAS: 178306-52-0
L-Proline Methyl Ester Hydrochlorid CAS: 2133-40-6
4,6-Dimethyl-2-(Methylsulfonyl)pyrimidine CAS: 35144-22-0

Chemical Properties:

Chemical Name	(S) -2- [(4,6-Dimethylpyrimidin-2-yl)oxy]-3-Methoxy-3,3-Diphenylpropionic Acid
Mashoko anoreva zvakafanana	(+-)-(2S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-Methoxy-3,3-Diphenylpropanoic Acid
Nhamba yeCAS	177036-94-1
Stock Status	MuStock, Kugadzirwa Kunokwira Kusvika Matani
Molecular Formula	C22H22N2O4
Molecular Weight	378.43
Kutenderera kwakananga [α]D20	+170.0° kusvika +176.0° (C=0.5, MeOH)
Melting Point	172.0~178.0℃(Zvita.)
Solubility	Yakanyanya Soluble muMethanol;Soluble muEthanol, Acetone;Insoluble muMvura
Brand	Ruifu Chemical

Zvinotsanangurwa:

Item	Zvinotsanangurwa
Chitarisiko	White kana Off-White Powder
Identification	HPLC;NMR;LC-MS
Related Substances
Kusachena Kwemunhu	≤0.50%
Zvose Zvisina Kuchena	<1.00%
Kurasika paKuomesa	≤0.50%
Residue paIgnition	≤0.20%
Heavy Metals	≤20ppm
Kuchena / Analysis Method	>99.0% (HPLC)
Test Standard	Enterprise Standard
Usage	Pharmaceutical Intermediates

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro

Zvakanakira:

FAQ:

Application:

(CAS: 177036-94-1) APIinosarudza endothelin-A (ETA) receptor antagonist yakaunzwa pamuromo kurapwa kwevarwere vane pulmonary arterial hypertension (PAH), kuvandudza kugona kwekuita uye kunonoka kuwedzera kwekiriniki.PAH chirwere chisingawanzoitiki chemagetsi maduku emapapu anoratidzwa nekuwedzera kwevascular uye kugadzirisa, zvichiita kuti kuwedzera kunowedzera mumapapu ekudzivirira kwevascular uye pulmonary arterial pressure, uye pakupedzisira, kukundikana kwe ventricular uye kufa nguva isati yakwana.Zviratidzo zvekutanga zvePAH zvinosanganisira zvishoma nezvishoma kutanga kupfupika kwekufema, kuneta, kufema, edema, uye kupera simba.Endothelin-1 (ET-1), ine simba vasoconstrictor uye yakatsetseka tsandanyama mitogen, chinhu chikuru chinobatsira kukurumidza kwechirwere, uye mhedzisiro yacho inopindirana kuburikidza nekuita kweETA uye ETB receptors.Muna Chikumi we2007, iyo FDA yakapa mvumo (CAS: 177036-94-1) API yekurapwa kamwe chete pazuva kwePAH.