Gefitinib Yepakati CAS 199327-61-2 Kuchena > 99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd ndiyo inotungamira kugadzira 7-Methoxy-6-(3-Morpholin-4-ylpropoxy)quinazolin-4(3H)-One (CAS: 199327-61-2) ine mhando yepamusoro, yepakati. yeGefitinib (CAS: 184475-35-2).Ruifu Chemical inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, sevhisi yakanakisa, idiki uye yakawanda huwandu huripo.Tenga Gefitinib Intermediates,Please contact: alvin@ruifuchem.com
| Chemical Name | 7-Methoxy-6-(3-Morpholin-4-ylpropoxy)quinazolin-4(3H)-Imwe |
| Mashoko anoreva zvakafanana | 7-Methoxy-6-(3-Morpholinopropoxy)quinazolin-4(3H)-Mumwe;7-Methoxy-6-[3-(4-Morpholinyl) propoxy] -4(3H) -Quinazolinone;7-Methoxy-6-(3-Morpholinopropoxy)quinazolin-4-One |
| kusachena | Gefitinib tsvina 5;Gefitinib EP Kusachena A |
| Stock Status | MuStock, Commercial Production |
| Nhamba yeCAS | 199327-61-2 |
| Molecular Formula | C16H21N3O4 |
| Molecular Weight | 319.36 g/mol |
| Melting Point | 242.0~247.0℃ |
| Density | 1.32±0.10 g/cm3 |
| COA & MSDS | Available |
| Origin | Shanghai, China |
| Brand | Ruifu Chemical |
| Items | Kuongorora Maitiro | Results |
| Chitarisiko | Ichena kusvika kuOff-White Powder | Zvinoenderana |
| Melting Point | 242.0~247.0℃ | 243.6~244.5℃ |
| Kurasika paKuomesa | <0.50% | 0.15% |
| Residue paIgnition | <0.20% | 0.11% |
| Kusachena Kumwechete | <0.50% | <0.30% |
| Zvose Zvisina Kuchena | <1.00% | 0.30% |
| Kuchena / Analysis Method | >99.0% (HPLC) | 99.7% |
| 1H NMR Spectrum | Zvinoenderana NeChimiro | Zvinoenderana |
| Mhedziso | Chigadzirwa chakaedzwa uye chinoenderana nezvakapihwa | |
| Application | Pakati peGefitinib (CAS: 184475-35-2) | |
Package:Fluorinated Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mudziyo wakavharwa zvakasimba uye chengeta munzvimbo inotonhorera, yakaoma (2~8℃) uye inofefeterwa nemhepo yakanaka kure nezvinhu zvisingaenderane.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.
Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
7-Methoxy-6- (3-Morpholin-4-ylpropoxy)quinazolin-4 (3H)-Imwe (CAS: 199327-61-2) inzvimbo yepakati / isina kuchena yeGefitinib (CAS: 184475-35-2).Gefitinib ndeye yakanyanya kujeka anti-tumor yakanangwa kurapa mushonga wakagadzirwa neAstraZeneca, UK.Gefitinib ndiyo yekutanga molecular yakanangwa mushonga wekurapa isiri-diki cell kenza yemapapu.Inoshanda nekusarudzika inhibiting iyo chiratidzo chekufambisa nzira ye epidermal kukura factor receptor tyrosine kinase (EGFR-TK).Muna Nyamavhuvhu 2002, Gefitinib yakatanga kutengeswa muJapan semutsetse wekutanga kurapwa kweasiri diki kenza yemapapu pasi pezita rekutengesa Iressa.Muna Chivabvu 2003, iyo US Food and Drug Administration yakabvumidza Gefitinib seyechitatu-mutsara monotherapy kune varwere vane yepamberi isiri-diki kenza yemapapu yemapapu avo vaisashanda neplatinum-based anticancer mishonga uye docetaxel chemotherapy.Parizvino, Gefitinib yakabvumidzwa neAustralia, Japan, Argentina, Singapore neSouth Korea kurapwa kwechirwere chegomarara chemapapu chepamusoro chisiri chidiki.Musi waKukadzi 28, 2005, iyo China Chikafu neDrug Administration yakabvumidza Gefitinib kurapwa kwepanzvimbo yepamusoro kana metastatic isiri-diki yekenza yemapapu (NSCLC) iyo yakambogamuchira chemotherapy.Izvo hazvisati zvatenderwa kushandiswa seyekutanga-mutsara kurapa kune yepamusoro NSCLC.Musi waChikunguru 1, 2009, European Medicines Agency yakabvumidza zviri pamutemo Gefitinib mutsara wekutanga, wepiri uye wechitatu kurapwa kwekenza yemuno kana metastatic isiri diki yekenza yemapapu ine EGFR gene mutations muvakuru.
