3-Chloro-4-(3-Fluorobenzyloxy)aniline CAS 202197-26-0 Lapatinib Intermediate Purity >98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira kugadzira 3-Chloro-4-(3-Fluorobenzyloxy)aniline (CAS: 202197-26-0) ine mhando yepamusoro.Ruifu Chemical inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, sevhisi yakanakisa, idiki uye yakawanda huwandu huripo.Tenga Lapatinib Intermediates,Please contact: alvin@ruifuchem.com
Chemical Name | 3-Chloro-4-(3-Fluorobenzyloxy)aniline |
Mashoko anoreva zvakafanana | 3-Chloro-4-[(3-Fluorophenyl)methoxy]aniline;4-(3-Fluorobenzyloxy) -3-Chlorobenzenamine;Lapatinib Yepakati B |
Stock Status | MuStock, Commercial Production |
Nhamba yeCAS | 202197-26-0 |
Molecular Formula | C13H11ClFNO |
Molecular Weight | 251.69 g/mol |
Melting Point | 78.0 kusvika 82.0 ℃ |
Density | 1.306±0.06 g/cm3 |
COA & MSDS | Available |
Muenzaniso | Available |
Origin | Shanghai, China |
Brand | Ruifu Chemical |
Items | Kuongorora Maitiro | Results |
Chitarisiko | Brown kusvika kuBlack Powder | Zvinoenderana |
Melting Point | 78.0 kusvika 82.0 ℃ | 80.7 ℃ |
Kurasika paKuomesa | <1.00% | Zvinoenderana |
Residue paIgnition | <0.50% | Zvinoenderana |
Kusachena kwakabatana neHPLC | <2.00% | 0.64% |
Kuchena / Analysis Method | >98.0% (HPLC) | 99.36% |
1H NMR Spectrum | Zvinoenderana NeChimiro | Zvinoenderana |
Mhedziso | Chigadzirwa chakaedzwa uye chinoenderana nezvakapihwa | |
Application | Pakati peLapatinib / Lapatinib Ditosylate Monohydrate |
Package:Fluorinated Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mudziyo wakavharwa zvakasimba uye chengeta muimba inotonhorera, yakaoma uye ine mhepo yakanaka kure nezvinhu zvisingaenderani.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.
Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
UN IDs 3077
HS Code 2921420090
Hazard Kirasi 9
Kurongedza Boka III
3-Chloro-4-(3-Fluorobenzyloxy)aniline (CAS: 202197-26-0) iri pakati nepakati mukugadzirwa kweLapatinib / Lapatinib Ditosylate Monohydrate.
Lapatinib mushonga unonangana negomarara rezamu rakagadzirwa neBritish GlaxoSmithKline Co. Human ErbB receptors ndeyemhando I tyrosine kinase (TK) receptor mhuri, kusanganisira ErbB1 (EGFR), ErbB2 (HER2), ErbB3 (HER3), uye ErbB4 (HER4) .Iyo ErbB-1 (EGFR) uye ErbB-2 (HER-2) receptors inowanzove yakanyanyisa kana kuchinjwa mune varwere vekenza.Human epidermal growth factor receptor 2 (ErbB-2, HER-2) inozivikanwa kuve munhu oncogene ane hukama nekenza yemazamu.Kuratidzwa kwayo kwepamusoro mugomarara rezamu kunowanzofanotaura lymph node metastasis uye kusarudzika kwebundu, nekusaziva zvakanaka.HER-2 ndeimwe yemamorekuru anonangwa ekurapa cancer yemazamu.Lapatinib inogona kuita panguva imwe chete paHer-1 Her-2.The biological mhedzisiro yeiyi nzira inotadzisa kuwanda uye kukura kwebundu masero akakura pane kungoshanda pane chimwe chinangwa.Musanganiswa weLapatinib neCapecitabine unoshandiswa kurapa varwere vane kenza yepazamu yepamusoro kana metastatic ine overexpression yemunhu epidermal receptor2, yakatorapwa neanthracyclines, paclitaxel, uye trastuzumab.Miedzo yemakiriniki yakaratidza kuti Lapatinib zvakare inobata HER2-mhando yekenza varwere vane Herceptin kuramba.
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