1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one CAS 27387-31-1 Ondansetron HCl Dihydrate Intermediate Purity>99.0% (HPLC)

Tsanangudzo Pfupi

1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-imwe

CAS: 27387-31-1

Kuchena:> 99.0% (HPLC)

Chitarisiko: Muchena kana Kunze-Ichena Crystalline Powder

Pakati peOndansetron Hydrochloride Dihydrate

Bata: Dr. Alvin Huang

Nharembozha/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira kugadzira 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one (CAS: 27387-31-1) ine mhando yepamusoro.Ruifu Chemical inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, sevhisi yakanakisa, idiki uye yakawanda huwandu huripo.Please contact: alvin@ruifuchem.com

Related Intermediates:

Inoenderana Pakati peOndansetron Hydrochloride Dihydrate

1,3-Cyclohexanedione	CAS 504-02-9
1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-imwe	CAS 27387-31-1
Ondansetron Hydrochloride Dihydrate	CAS 103639-04-9

Chemical Properties:

Chemical Name	1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-imwe
Mashoko anoreva zvakafanana	1,2,3,4-Tetrahydro-9-Methylcarbazol-4-imwe;1,2,3,4-Tetrahydro-9-Methyl-4-Oxocarbazole
Stock Status	Mudura
Kusachena	Ondansetron USP Related Compound C;Ondansetron EP Kusachena C;Ondansetron Hydrochloride Dihydrate Kusachena C
Nhamba yeCAS	27387-31-1
Molecular Formula	C13H13NO
Molecular Weight	199.25 g/mol
Melting Point	199.0 kusvika 203.0 ℃
Density	1.21±0.10 g/cm3
COA & MSDS	Available
Brand	Ruifu Chemical

Zvinotsanangurwa:

Items	Kuongorora Maitiro	Results
Chitarisiko	Ichena kusvika kuOff-White Crystalline Powder	Zvinoenderana
Melting Point	199.0 kusvika 203.0 ℃	200.0 kusvika 202.0 ℃
Kusachena Kumwechete	<0.50%	Zvinoenderana
Zvose Zvisina Kuchena	<1.00%	Zvinoenderana
Kuchena / Analysis Method	>99.0% (HPLC)	99.65%
1 H NMR Spectrum	Inopindirana neChimiro	Zvinoenderana
Mhedziso	Chigadzirwa chacho chakaedzwa uye chinoenderana nezvinodiwa

Pakeji/Kuchengeta/Shipping:

Package:Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumudziyo wakavharwa zvakasimba.Chengetedza muimba yekuchengetera inotonhorera, yakaoma uye ine mhepo yakanaka kure nezvinhu zvisingaenderane.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.

Zvakanakira:

Yakakwana Capacity: Inokwana zvivakwa uye matekiniki

Professional Service: Imwe inomira kutenga sevhisi

OEM Package: Tsika pasuru uye label iripo

Fast Delivery: Kana iri mukati me stock, mazuva matatu ekutumira anovimbiswa

Yakagadzika Supply: Chengetedza zvine musoro stock

Tsigiro yehunyanzvi: Tekinoroji mhinduro iripo

Tsika Synthesis Service: Kubva pamagiramu kusvika makirogiramu

Hunhu Hwepamusoro: Yakagadzira yakakwana yemhando yekusimbisa system

FAQ:

Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.

Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.

Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.

HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.

Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.

Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.

MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.

Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.

Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.

Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.

Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.

Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.

27387-31-1 - Njodzi uye Kuchengeteka:

Risk Codes
R36/37/38 - Kushungurudza maziso, kufema system uye ganda.
R52/53 - Inokuvadza kune zvipenyu zvemvura, zvinogona kukonzera mhedzisiro yakaipa kwenguva refu munzvimbo yemvura.
R25 - Muchetura kana ukamedzwa
Tsanangudzo Yekuchengetedza
S22 - Usafeme guruva.
S24/25 - Dzivisa kusangana neganda nemeso.
S61 - Dzivisa kusunungurwa kune zvakatipoteredza.Tarisa kune yakakosha mirairo / kuchengetedza data mapepa.
S45 - Kana pakaitika tsaona kana ukanzwa usinganzwe zvakanaka, tsvaga zano rekurapa nekukasira (ratidza chinyorwa pese pazvinogoneka.)
UN IDs UN 2811 6.1 / PGIII

27387-31-1 - Application:

1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one (CAS: 27387-31-1) inoshandiswa sepakati peOndansetron Hydrochloride Dihydrate (CAS: 103639-04-9).Iyo United Kingdom Glaxo kambani kuvandudza, 1990 muFrance, iyo United Kingdom musika.Chigadzirwa chacho chinonyanya kusarudzwa serotonin (5-HT3) receptor antagonist, inogona kudzivisa Nausea inokonzerwa nekemotherapy uye radiotherapy Vomit, ine simba guru uye high selectivity, inogona kudzora ura hudiki uye CTZ receptors inokonzerwa nekukurudzira kweVomit.Inokodzera kurapwa kweNausea Vomit inokonzerwa nechemotherapy uye radiotherapy, uye inogona zvakare kushandiswa kudzivirira nekurapa Nausea Marutsi anokonzerwa mushure mekuvhiyiwa.

Ondansetron, granisetron uye dolasetron mishonga mitatu yeantiemetic inowanzoshandiswa mukiriniki, ondansetron ine simba, inosarudza uye inogadziriswa 5-hydroxytryptamine (5-HT3) receptor blocker yeAlpha 1, Alpha 2, beta 1, Beta 2 adrenergic receptors uye histamine H1, h2 receptor ine zvishoma, uye haina antagonistic effect paH receptor, pakati uye peripheral dopaminergic receptors, uye inogona kudzivisa Nausea uye Kurutsirwa kunokonzerwa nechemotherapy uye radiotherapy.Kuenzaniswa ne metoclopramide, Iyo antiemetic mhedzisiro yaive yakasimba uye pakanga pasina extrapyramidal reaction.Cisplatin, cyclophosphamide, doxorubicin inokonzerwa neRutsi inogona kuburitsa nekukurumidza uye yakasimba anti-nausea maitiro.Inokodzera kurapwa kwecytotoxic zvinodhaka zvinokonzerwa nechemotherapy uye neradiation therapy Nausea Vomit, asiwo kudzivirira uye kurapwa kweNausea Vomit inokonzerwa nekuvhiyiwa.ondansetron inoshanda sechiteshi chekufambisa pakati peiyo activated visceral afferent nerves mugastrointestinal turakiti uye Marutsi epakati mumusana, zvichikonzera dumbu uye diaphragmatic kufamba.Chemotherapy mishonga uye radiation therapy inogona kukonzera kusunungurwa kwe5-HT mudumbu diki, uye Vomit reflex inokonzerwa nekukurudzira kwevagus nerve kuburikidza ne5-HT3 receptor.Ichi chigadzirwa chinovhara kuitika kweiyi reflex, uku ichivharira Vomit inokonzereswa nepakati chiito.Iyo nzira yekuita yakanga isingazivikanwe yeNausea Vomit mushure mekuvhiyiwa.Ondansetron yakasanganiswa nedexamethasone inogona kuwedzera antiemetic effect.