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Ibrutinib Yepakati CAS 330792-70-6 Kuchena > 98.0% (HPLC) Featured Image
  • Ibrutinib Yepakati CAS 330792-70-6 Kuchena > 98.0% (HPLC)

Ibrutinib Yepakati CAS 330792-70-6 Kuchena > 98.0% (HPLC)

Tsanangudzo Pfupi:

5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile

CAS: 330792-70-6

Kuchena:> 98.0% (HPLC)

Chitarisiko: Off-White kusvika Chiedza Yellow Powder

Pakati peIbrutinib (CAS: 936563-96-1) 

Bata: Dr. Alvin Huang

Nharembozha/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Pakati peIbrutinib:

Ibrutinib CAS 936563-96-1
3-Hydroxypiperidine CAS 6859-99-0
1-Boc-3-Hydroxypiperidine CAS 85275-45-2
(S) -1-Boc-3-Hydroxypiperidine CAS 143900-44-1
4-Phenoxybenzoic Acid CAS 2215-77-2
4-Phenoxyphenylboronic Acid CAS 51067-38-0
4-Aminopyrazolo[3,4-d]pyrimidine CAS 2380-63-4
4-Amino-3-Iodo-1H-Pyrazolo[3,4-d]pyrimidine CAS 151266-23-8
Ibrutinib Deacryloylpiperidine CAS 330786-24-8
5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile CAS 330792-70-6

Chemical Properties:

Chemical Name 5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile
Mashoko anoreva zvakafanana Ibrutinib Pakati N-3;3-Amino-5-(4-Phenoxyphenyl)pyrazole-4-Carbonitrile;3-Amino-4-Cyano-5-(4-Phenoxyphenyl)pyrazole;5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile
Nhamba yeCAS 330792-70-6
Stock Status MuStock, Kugadzirwa Kunokwira Kusvika Matani
Molecular Formula C16H12N4O
Molecular Weight 276.29
Density 1.37±0.10 g/cm3
COA & MSDS Available
Origin Shanghai, China
Brand Ruifu Chemical

Zvinotsanangurwa:

Item Zvinotsanangurwa
Chitarisiko Off-White kusvika Chiedza Yellow Powder
Kuchena / Analysis Method >98.0% (HPLC)
Kurasika paKuomesa <1.00%
Residue paIgnition <0.50%
Zvose Zvisina Kuchena <2.00%
Heavy Metals (as Pb) <20ppm
1 H NMR Spectrum Zvinoenderana NeChimiro
Test Standard Enterprise Standard
Usage Pakati peIbrutinib (CAS: 936563-96-1)

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro.

Zvakanakira:

1

FAQ:

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330792-70-6 - Application:

5-Amino-3- (4-Phenoxyphenyl) -1H-Pyrazole-4-Carbonitrile (CAS: 330792-70-6) iri pakati peIbrutinib (CAS: 936563-96-1).Ibrutinib inoratidza iyo ine simba uye isingachinjiki inhibitory mhedzisiro uye kusarudza kweBtk enzymatic chiitiko.MuBCR nzira-yakagadzirwa DOHH2 cell line, Ibrutinib inhibits autophosphorylation yeBtk, phosphorylation yeBtk's physiological substrate PLCγ, uye phosphorylation yeimwe downstream kinase, ERK ine IC50 ye11 nM, 29 nM uye 13 nM, maererano.Ibrutinib inoratidza yakakura-inotsamira uye inoenderana nenguva induction ye cytotoxicity mune asingaperi lymphocytic leukemia (CLL) masero.Mukuwedzera, Ibrutinib induces sero kufa zvichienderana necaspase pathway activation uye inopesana nekugona kwemasero eCLL kuwanda mushure mekusaina kweTLR.

Nyora meseji yako pano uye titumire kwatiri