CAS 361440-67-7 Kuchena > 98.5% (HPLC) Factory

Tsanangudzo Pfupi:

(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo [3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester

CAS: 361440-67-7

Kuchena:> 98.5% (HPLC)

Kuonekwa: White Powder

Yepakati pe API (CAS: 361442-04-8)

E-Mail: alvin@ruifuchem.com

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Tsanangudzo:

Ruifu Chemical Supply Related Intermediates
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(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo [3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester CAS 361440-67-7
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Chemical Properties:

Chemical Name	(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester
Mashoko anoreva zvakafanana	N-Boc-L-cis-4,5-Methanoprolineamide;N-Boc-cis-4,5-Methano-L-Prolinamide;tert-Butyl (1S,3S,5S)-3-Carbamoyl-2-Azabicyclo[3.1.0]hexane-2-Carboxylate
Nhamba yeCAS	361440-67-7
Nhamba yeCAT	RF-PI1990
Stock Status	MuStock, Kugadzirwa Kunokwira Kusvika Matani
Molecular Formula	C11H18N2O3
Molecular Weight	226.27
Boiling Point	388.9±21.0℃
Density	1.228
Brand	Ruifu Chemical

Zvinotsanangurwa:

Item	Zvinotsanangurwa
Chitarisiko	White Powder
Kuchena / Analysis Method	>98.5% (HPLC)
Kurasika paKuomesa	<0.50%
Residue paIgnition	<0.20%
Kusachena Kwemunhu	<1.00%
Zvose Zvisina Kuchena	<1.50%
Test Standard	Enterprise Standard
Usage	Yepakati pe API (CAS: 361442-04-8)

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro

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Application:

(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester (CAS: 361440-67-7) iri pakati pe API (CAS: 361442 -04-8).(CAS: 361442-04-8) inonzi oral hypoglycemic (anti-diabetic drug) yedipeptidyl peptidase-4 (DPP-4) inhibitor class yemishonga.Kuvandudzwa kwepakutanga kwaive chete naBristol-Myers Squibb;muna 2007 AstraZeneca yakabatana neBristol-Myers Squibb kuti vabatane kugadzira komboni yekupedzisira uye nekubatana pakushambadzira kwemushonga.Muna June 2008, zvakaziviswa kuti Onglyza ichava zita rekutengeserana pasi paro richatengeswa.API (CAS: 361442-04-8) inoshandiswa se monotherapy kana kusanganiswa nemamwe madhiragi ekurapa chirwere cheshuga chechipiri.Inotorwa nekukurumidza mushure mekutonga nemuromo uye ine pharmacokinetic profil inoenderana kamwe chete zuva nezuva dosing.Inotamba iyo kuburikidza nekudzivisa GLP-l kuderedzwa.GLP-I ndiwo mahomoni anogadzirwa mumatumbo mushure mekutora chikafu.