5-(2-Pyridyl)-1,2-Dihydropyridin-2-imwe CAS 381233-78-9 Perampanel Pakati Pekuchena>98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira kugadzira 5-(2-Pyridyl)-1,2-Dihydropyridin-2-one ([2,3'-Bipyridin] -6'(1'H)-imwe) (CAS: 381233-78-9) nehupamhi hwepamusoro, hwepakati pePerampanel (CAS: 380917-97-5).Ruifu Chemical inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, sevhisi yakanakisa, idiki uye yakawanda huwandu huripo.Tenga Perampanel yepakati,Please contact: alvin@ruifuchem.com
| Chemical Name | 5-(2-Pyridyl) -1,2-Dihydropyridin-2-imwe |
| Mashoko anoreva zvakafanana | [2,3'-Bipyridin]-6'(1'H)-imwe;5-(Pyridin-2-yl)pyridin-2(1H)-imwe;5-(Pyridin-2-yl)-2(1H)-Pyridone;5-(2-Pyridyl)pyridin-2(1H)-imwe;5-Pyridin-2-yl-1H-Pyridin-2-imwe;5-(Pyridin-2-yl) -1,2-Dihydropyridin-2-imwe;Perampanel Kusachena 1 |
| Stock Status | MuStock, Commercial Production |
| Nhamba yeCAS | 381233-78-9 |
| Molecular Formula | C10H8N2O |
| Molecular Weight | 172.18 g/mol |
| Melting Point | 71.0 ~ 75.0℃ |
| Density | 1.221±0.06 g/cm3 |
| COA & MSDS | Available |
| Origin | Shanghai, China |
| Category | Pakati Perampanel (CAS: 380917-97-5) |
| Sherufu Hupenyu | Mwedzi 24 Kana Yakachengetwa Zvakanaka |
| Brand | Ruifu Chemical |
| Items | Kuongorora Maitiro | Results |
| Chitarisiko | Hupfu Huchena kusvika Hunenge Huchena | White Powder |
| Kuchena / Analysis Method | >98.0% (HPLC) | 99.7% |
| Mvura naKarl Fischer | <1.00% | 0.58% |
| Kusachena Kumwechete | <1.00% | Zvinoenderana |
| Zvose Zvisina Kuchena | <2.00% | 0.30% |
| 1H NMR Spectrum | Zvinoenderana NeChimiro | Zvinoenderana |
| Mhedziso | Chigadzirwa chakaedzwa uye chinoenderana nezvakapihwa | |
| Application | Pakati Perampanel (CAS: 380917-97-5) | |
Package:Fluorinated Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mudziyo wakavharwa zvakasimba uye chengeta muimba inotonhorera, yakaoma uye ine mhepo yakanaka kure nezvinhu zvisingaenderani.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.
Properties: Ichena kusvika Kunenge Ichena Hupfu
Solvent: Tetrahydrofuran, Toluene, Ethylacetate, Ethanol, Methanol, tert-Butyl Methyl Ether, Petroleum Ether, n-Hexane, Dichloromethane
Tarisa: Zvine hukama: Tora chigadzirwa ichi wochinatsa ne diluent (mobile phase mvura: methanol (50∶50)) kugadzira mhinduro ine inenge 0.5mg pa1ml semhinduro yechigadzirwa chebvunzo.Zvinoenderana nepamusoro kuita kwemvura chromatography (Chinese Pharmacopoeia 2010 Edition II Appendix Ⅴ D), iyo silica gel (ZORBAX SB-C18 4.6×250mm,5m) yakashandiswa seyekuzadza.Nharembozha chikamu A yaive mvura, nharembozha B yaive methanol, uye yekuona wavelength yaive 254nm.Mwero wekuyerera waive 1.0ml/min uye tembiricha yembiru yaive tembiricha yemukamuri.5μl yemhinduro yebvunzo yakayerwa nemajekiseni uye jekiseni mune yemvura chromatograph kunyora chromatogram.Zvinoenderana neiyo nharaunda normalization nzira, zvirimo zvechigadzirwa ichi hazvisi pasi pe98%.Kana paine nhongonya dzehutsvina muchromatogram yemhinduro yechigadzirwa chebvunzo, iyo nzvimbo yekusachena yepamusoro haifanire kudarika 1.0%, uye huwandu hwenzvimbo yekusachena haipfuure 2.0%.
Unyoro: Tora chigadzirwa ichi, shandisa mwando tester, maererano neKarl Fischer's nzira (Chinese Pharmacopoeia 2010 edition II Appendix Ⅷ M nzira yekutanga A) kutsunga, hunyoro hwehunyoro hahungapfuuri 1.0%.
Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
5-(2-Pyridyl) -1,2-Dihydropyridin-2-imwe ([2,3'-Bipyridin] -6'(1'H)-imwe) (CAS: 381233-78-9), iri pakati pe Perampanel (CAS: 380917-97-5).Perampanel (ane rezenisi muna 2012) chizvarwa chechitatu cheAED chinozivikanwa nezita remhando yeFycompa® (Eisai, Hatfield) muUK neBanzel® (Eisai, Hatfield) muUSA.Adjunctive kurapwa kwefocal seizures ine kana isina yechipiri generalization uye primary generalized tonic-clonic seizures.Muna Gumiguru 2012, iyo US FDA yakabvumidza perampanel kurapwa kwechikamu chekutanga pfari muvarwere vane pfari vangangoita makore gumi nemaviri.Perampanel ndiye wekutanga AMPA receptor antagonist kugamuchira FDA mvumo seAED.AMPA glutamate receptors anowanikwa zvakanyanya pane postsynaptic neurons muuropi.Semunhu anosarudza, asingakwikwidzi anopikisa we AMPA, parampanel inodzivirira ion chiteshi kuvhurwa uye inoderedza kupararira kwekuita.
