Lapatinib Ditosylate Monohydrate CAS 388082-78-8 Kuchena > 99.0% (HPLC)
Chemical Name | Lapatinib Ditosylate Monohydrate |
Mashoko anoreva zvakafanana | N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine |
Nhamba yeCAS | 388082-78-8 |
Stock Status | Mudura |
Molecular Formula | C29H26ClFN4O4S·2(C7H8O3S)·H2O |
Molecular Weight | 943.48 |
COA & MSDS | Available |
Origin | Shanghai, China |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Yero Yero kusvika Yero yeCrystalline Powder |
Kuchena / Analysis Method | ≥99.0% (HPLC) |
Melting Point | 240.0~242.0℃ |
Kunyorova (KF) | 1.9~2.4% |
Kusachena Kumwechete | ≤0.50% |
Zvose Zvisina Kuchena | ≤1.00% |
Heavy Metals (as Pb) | ≤20ppm |
Test Standard | Enterprise Standard |
Usage | API;Kurapa varwere vane gomarara rezamu |
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro
Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8) ndiyo ditosylate munyu we.CAS 231277-92-2, yekugadzira, yemuromo-inoshanda quinazoline ine inogona kuita antineoplastic chiitiko.Iyo inodzosera inovhara phosphorylation ye epidermal growth factor receptor (EGFR), ErbB2, uye Erk-1 uye-2 uye AKT kinases;iyo inodzivisawo cyclin D mapuroteni mazinga muvanhu tumor cell mitsara uye xenografts.EGFR uye ErbB2 zvakabatanidzwa mukukura kwemhando dzakasiyana dzebundu.Yakatangwa kurapwa kwepamusoro kana metastatic HER2 (ErbB2) kenza yemazamu yakanaka muvakadzi vakambowana kurapwa.Mushonga wakawanikwa uye wakagadzirwa neGlaxoSmithKline.