Apixaban Yepakati CAS 545445-44-1 Kuchena > 98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira kugadzira 3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-imwe (CAS: 545445 -44-1) nehupamhi hwepamusoro, huri pakati peApixaban (CAS: 503612-47-3).Ruifu Chemical inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, sevhisi yakanakisa, idiki uye yakawanda huwandu huripo.Tenga Apixaban Intermediates,Please contact: alvin@ruifuchem.com
| Chemical Name | 3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-imwe |
| Mashoko anoreva zvakafanana | Apixaban Pakati 1;5,6-Dihydro-3- (4-Morpholinyl) -1-[4-(2-Oxo-1-Piperidinyl) phenyl] -2(1H)-Pyridinone;5-Morpholin-4-yl-1- [4- (2-Oxopiperidin-1-yl) phenyl] -2,3-Dihydropyridin-6-imwe;Apixaban Impurity A |
| Stock Status | MuStock, Commercial Production |
| Nhamba yeCAS | 545445-44-1 |
| Molecular Formula | C20H25N3O3 |
| Molecular Weight | 355.43 g/mol |
| Melting Point | >199℃(Zvita.) |
| Density | 1.267 g/mL |
| COA & MSDS | Available |
| Origin | Shanghai, China |
| Category | Pakati peApixaban (CAS: 503612-47-3) |
| Brand | Ruifu Chemical |
| Items | Zvinotsanangurwa | Results |
| Chitarisiko | Light Yellow Powder | Light Yellow Powder |
| Kurasika paKuomesa | <0.50% | 0.16% |
| Residue paIgnition | <0.20% | 0.07% |
| Kuchena / Analysis Method | >98.0% (HPLC Area) | 99.12% |
| Chero Kusachena Kwemunhu | <0.50% | <0.50% |
| Zvose Zvisina Kuchena | <2.00% | 0.88% |
| 1H NMR Spectrum | Zvinoenderana NeChimiro | Conforms |
| LC-MS yeKuzivikanwa | Conforms | Conforms |
| Mhedziso | Chigadzirwa chakaedzwa uye chinoenderana nezvakapihwa | |
| Application | Pakati peApixaban (CAS: 503612-47-3) | |
Package:Fluorinated Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mudziyo wakavharwa zvakasimba uye chengeta muimba inotonhorera, yakaoma uye ine mhepo yakanaka kure nezvinhu zvisingaenderani.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.
Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-one (CAS: 545445-44-1) iri pakati peApixaban (CAS: 503612-47-3).
Apixaban rudzi rutsva rweoral Xa factor inhibitor yakabatanidzwa pamwe chete neBristol-Myers Squibb uye Pfizer.Zita rekutengesa ndiro Eratol, inova rudzi rutsva rwemuromo anticoagulant.Nekudzivisa yakakosha coagulation factor Xa, Apixaban inogona kudzivirira thrombin kugadzirwa uye thrombosis.Musi waApril 26, 2007, Bristol-Myers Squibb akabatana maoko naPfizer kuzivisa kushanda pamwe mukugadzirwa kweApixaban yemuromo anticoagulant yeBristol-Myers Squibb seimwe nzira yakagadziridzwa yeWarfarin.Muna Chivabvu 2011, Apixaban ndiye akatanga kubvumidza kudzivirirwa kwevenous thrombosis muvarwere vakura vanovhiyiwa kusarudzwa kwehudyu kana kutsiva mabvi munyika dze27 EU, Iceland neNorway.Musi waNovember 20, 2012, European Commission yakabvumira Ererto (Apixaban) yekudzivirira sitiroko uye systemic embolism muvarwere vakuru vane non-valvular atrial fibrillation (NVAF) ine imwe kana yakawanda yengozi.Zvadaro, Canadian Food and Drug Administration, Japan, uye US FDA yakabvumira Ererto (Apixaban) yekudzivirira sitiroko uye systemic embolism muvarwere vakura vane non-valvular atrial fibrillation (NVAF) ine imwe kana yakawanda yengozi.Musi waKubvumbi 12, 2013, iyo itsva anticoagulant drug Eloto (ELIQUIS) (Apixaban) yakabatanidzwa neBristol-Myers Squibb uye Pfizer yakaziviswa zviri pamutemo kuti yakanyorwa muChina.
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