Trelagliptin Succinate Yepakati CAS 865759-24-6 Kuchena > 98.0% (HPLC)

Tsanangudzo Pfupi

Trelagliptin Succinate Yepakati-int D

CAS: 865759-24-6

Kuchena:> 98.0% (HPLC)

Chitarisiko: Off-White kusvika Chiedza Yero Crystal

Yepakati yeTrelagliptin Succinate (CAS: 1029877-94-8) yekurapa Type 2 Diabetes

Bata: Dr. Alvin Huang

Nharembozha/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Commerce Supply Trelagliptin Succinate Related Intermediates:
6-Chloro-3-Methyluracil CAS 4318-56-3
2-Cyano-5-Flurobenzyl Bromide CAS 421552-12-7
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
Trelagliptin Succinate Yepakati-int D CAS 865759-24-6
Trelagliptin Succinate CAS 1029877-94-8
Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	Trelagliptin Succinate Yepakati-int D
Mashoko anoreva zvakafanana	2-((6-Chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl) -4-fluorobenzonitrile;2--[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-4-fluorobenzonitrile
Kusachena	Trelagliptin Kusachena 17
Stock Status	MuStock, Commerce Scale
Nhamba yeCAS	865759-24-6
Molecular Formula	C13H9ClFN3O2
Molecular Weight	293.68 g/mol
Density	1.49±0.10 g/cm3
Storage Temp.	Nzvimbo Inotonhorera & Yakaoma
COA & MSDS	Available
Brand	Ruifu Chemical

Zvinotsanangurwa:

Items	Kuongorora Maitiro	Results
Chitarisiko	Off-White kusvika Chiedza Yero Crystal	Conforms
Identification
HPLC	Nguva yekuchengeta yeyedzo sampuli huru yepamusoro inopindirana nereferensi chiyero	Conforms
IR - Infrared Spectrum	IR Absorption spectra yemuenzaniso uye yakajairwa inowirirana	Conforms
Inspection
Kurasika paKuomesa	<0.50%	0.3%
Zvose Zvisina Kuchena	<2.00%	Conforms
Kuchena / Analysis Method	>98.0% (HPLC)	99.1%
Mhedziso	Chigadzirwa chacho chakaedzwa uye chinoenderana nezvinodiwa

Pakeji/Kuchengeta/Shipping:

Package:Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma uye ine mhepo yakanaka kure nezvinhu zvisingaenderane.Dzivirira kubva kuchiedza uye unyoro.Dzivisa chiedza;Airtight.
KutumiraKuendesa kupasirese neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.

Zvakanakira:

Yakakwana Capacity: Inokwana zvivakwa uye matekiniki

Professional Service: Imwe inomira kutenga sevhisi

OEM Package: Tsika pasuru uye label iripo

Fast Delivery: Kana iri mukati me stock, mazuva matatu ekutumira anovimbiswa

Yakagadzika Supply: Chengetedza zvine musoro stock

Tsigiro yehunyanzvi: Tekinoroji mhinduro iripo

Tsika Synthesis Service: Kubva pamagiramu kusvika makirogiramu

Hunhu Hwepamusoro: Yakagadzira yakakwana yemhando yekusimbisa system

FAQ:

Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.

Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.

Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.

HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.

Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.

Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.

MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.

Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.

Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.

Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.

Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.

Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.

Application:

2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile (CAS: 865759-24-6) inoshandiswa se yepakati yeTrelagliptin Succinate (CAS: 1029877-94-8).Trelagliptin Succinate, yakagadzirwa naTakeda, Japan, yakatangwa munaKurume 2015, pasi pezita rekutengesa reZafatek, inoshandiswa kurapa chirwere cheshuga cherudzi rwechipiri.Trelagliptin ndeye ultra-refu-acting dipeptidyl peptidase IV (DPP-4) inhibitor nekusarudza uye nekuramba ichivharira DPP-4 kudzora mazinga eshuga.Trelagliptin ndiyo yekutanga vhiki nevhiki hypoglycemic mushonga pamusika, uye yakafanana DPP-4 inhibitors pamusika inoda kutorwa kamwe chete pazuva.Zafatek mishonga yakanakira pasina mubvunzo ichapa nzira dzekurapa dziri nyore kune vane chirwere cheshuga.Zvinotarisirwa kuvandudza zvakanyanya kureruka uye kutevedza kwevarwere.musi waKurume 26, 2015, hofori yemishonga yekuJapan Takeda yakazivisa kuti mushonga mutsva wechirwere cheshuga Zafatek wakabvumidzwa neJapan Ministry of Health, Labour and Welfare (MHLW) kurapa rudzi rwechipiri chirwere cheshuga.Mvumo inotaridza Zafatek kuve yekutanga svondo remuromo hypoglycemic mushonga pamusika munyika, uye zvakare inomiririra blockbuster yakadonhedzwa naTakeda mumusika weshuga.
Trelagliptin ndeye kamwe-pasvondo dipeptidyl peptidase IV (DPP-4) inhibitor inodzora mazinga eshuga yeropa nekusarudza uye nekuramba ichivharira DPP-4.DPP-4 is enzyme inogona kutanga kusashanda kwe incretin (glucagon-like peptide -1 (GLP-1) uye glucose-inotsamira insulinotropic polypeptide (GIP)), iyo inoita basa rakakosha mukudzora shuga yeropa.Inhibition yeDPP-4 inogona kuwedzera shuga yeropa-inotsamira insulin secretion, nokudaro kudzora shuga yeropa.Kutumirwa kweTrelagliptin NDA kunoenderana nekugona uye kuchengetedza data kubva akati wandei chikamu III miedzo yekiriniki yakaitwa muvarwere vekuJapan vane Type 2 chirwere cheshuga.Kushanda kweTrelagliptin kwakasimbiswa mumiedzo yese, uye ine kuchengetedzwa kwakanaka uye kushivirira.Trelagliptin Administration kamwe pasvondo inogona kunyatso kudzora shuga yeropa uye inotarisirwa kuvandudza kutevedza kwemishonga yevarwere.