Enzalutamide CAS 915087-33-1 Kuchena >99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira kugadzira Enzalutamide (CAS: 915087-33-1) ine mhando yepamusoro.Ruifu Chemical inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, sevhisi yakanakisa, idiki uye yakawanda huwandu huripo.Kutenga Enzalutamide (CAS: 915087-33-1),Please contact: alvin@ruifuchem.com
Chemical Name | Enzalutamide |
Mashoko anoreva zvakafanana | MDV-3100;MDV 3100;4- [3- [4-Cyano-3-(Trifluoromethyl)) phenyl] -5,5-Dimethyl-4-Oxo-2-Thioxo-1-Imidazolidinyl]-2-Fluoro-N-Methylbenzamide |
Stock Status | MuStock, Kukwanisa Kugadzira 50 kgs pamwedzi |
Nhamba yeCAS | 915087-33-1 |
Molecular Formula | C21H16F4N4O2S |
Molecular Weight | 464.44 g/mol |
Melting Point | 198.0 ~ 200.0℃ |
Density | 1.49 |
COA & MSDS | Available |
Origin | Shanghai, China |
Brand | Ruifu Chemical |
Items | Zvinotsanangurwa | Results |
Chitarisiko | Ichena kusvika Kuchena-Ichena Solid Powder | Zvinoenderana |
Kuchena / Analysis Method | >99.0% (HPLC) | 99.57% |
Mvura naKarl Fischer | <0.50% | 0.23% |
Residue paIgnition | <0.10% | 0.06% |
Masimbi anorema (Pb) | ≤20ppm | <10ppm |
Related Substances | ||
Max.Kusachena Kumwechete | <0.50% | <0.50% |
Zvose Zvisina Kuchena | <1.00% | 0.43% |
Infrared Spectrum | Zvinoenderana NeChimiro | Zvinoenderana |
1H NMR Spectrum | Zvinoenderana NeChimiro | Zvinoenderana |
Mhedziso | Chigadzirwa chakaedzwa uye chinoenderana nezvakapihwa |
Package:Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mudziyo wakavharwa zvakasimba uye chengeta munzvimbo inotonhorera, yakaoma (2~8℃) uye inofefeterwa nemhepo yakanaka kure nezvinhu zvisingaenderane.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.
Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
Enzalutamide (CAS: 915087-33-1) inopikisa androgen-receptor (AR) ine IC50 ye36 nM, iyo inovhara androgens kubva pakusungirirwa kune androgen receptor uye inodzivirira nyukireya translocation uye co-activator recruitment ye ligand-receptor complex.Enzalutamide yakaratidzawo kukurudzira tumor cell apoptosis, uye haina agonist chiitiko.Enzalutamide mumiriri wekurapa kwecastration-resistant cancer yeprostate.Enzalutamide, chizvarwa chechipiri androgen receptor (AR) chiratidzo inhibitor.Inokwanisa kuvharidzira kusunga kwe androgens kune AR, AR nuclear translocation, uye kushamwaridzana kweAR neDNA.Muna Nyamavhuvhu 2012, iyo FDA yakabvumidza Enzalutamide, inotengeswa neMedivation uye Astellas Pharma US kurapwa kwe metastatic castration-resistant cancer cancer (CRPC), kunyanya kune avo varwere vakambogamuchira Docetaxel.