4-Chloro-6-Iodoquinazoline CAS 98556-31-1 Kuchena >98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira kugadzira 4-Chloro-6-Iodoquinazoline (CAS: 98556-31-1) ine mhando yepamusoro.Ruifu Chemical inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, sevhisi yakanakisa, idiki uye yakawanda huwandu huripo.Tenga 4-Chloro-6-Iodoquinazoline,Please contact: alvin@ruifuchem.com
Chemical Name | 4-Chloro-6-Iodoquinazoline |
Mashoko anoreva zvakafanana | 6-Iodo-4-Chloroquinazoline |
Stock Status | MuStock, Commercial Production |
Nhamba yeCAS | 98556-31-1 |
Molecular Formula | C8H4ClIN2 |
Molecular Weight | 290.49 g/mol |
Melting Point | 175.0 kusvika 179.0 ℃ |
Density | 2.017±0.06 g/cm3 |
Refractive Index n20/D | 1.739 |
Sensitive | Air Sensitive |
COA & MSDS | Available |
Origin | Shanghai, China |
Brand | Ruifu Chemical |
Items | Kuongorora Maitiro | Results |
Chitarisiko | Earth Yellow kusvika Yellowish-Brown Powder | Earth Yellow Powder |
Melting Point | 175.0 kusvika 179.0 ℃ | 177.2℃ |
Kurasika paKuomesa | <1.00% | 0.15% |
Kuchena / Analysis Method | >98.0% (HPLC) | 98.43% |
1H NMR Spectrum | Zvinoenderana NeChimiro | Zvinoenderana |
Mhedziso | Chigadzirwa chakaedzwa uye chinoenderana nezvakapihwa | |
Application | Pakati peLapatinib / Lapatinib Ditosylate Monohydrate |
Package:Fluorinated Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mudziyo wakavharwa zvakasimba uye chengeta muimba inotonhorera, yakaoma uye ine mhepo yakanaka kure nezvinhu zvisingaenderani.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.
Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
4-Chloro-6-Iodoquinazoline (CAS: 98556-31-1) iri pakati pekugadzirisa kweLapatinib (CAS: 231277-92-2) / Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8).
Lapatinib itsva yekenza yemazamu yakanangwa mushonga wekurapa wakagadzirwa uye wakagadzirwa neGlaxoSmithKline, iyo yakatenderwa neUS Food and Drug Administration musi waKurume 13, 2007. Chiratidzo chazvino chakabvumidzwa chinosanganiswa ne capecitabine yekenza yepamusoro kana metastatic yemazamu, uye varwere vekenza yemazamu. inofanira kurapwa nemimwe mishonga yekutanga.Zita rayo rekutengeserana muUnited States ndiTykerb.Musi waZvita 14, 2007, European Medicines Agency (EMEA) yakabvumidza kunyorwa kweLapatinib muEurope pasi pezita rekutengesa Tyverb.Molecular yakanangwa kurapwa kwegomarara rezamu inoreva kurapwa kweoncogenes uye zvine chekuita nekutaura zvigadzirwa zvine chekuita nekuitika uye kukura kwegomarara rezamu.Molecular yakanangwa zvinodhaka inhibisa kana kuuraya bundu maseru nekuvharira kutapurirana chiratidzo mumamota maseru kana maseru ane hukama kudzora shanduko musero gene kutaura.Lapatinib ndeyemuromo diki molecule epidermal kukura factor tyrosine kinase inhibitor.Miedzo yemakiriniki yakaratidza kuti kune HER2 varwere vekenza yemazamu avo vakatanga kuramba Roche's Herceptin (Herceptin), Lapatinib ine yakanaka kiriniki mhedzisiro.In vitro bvunzo, Lapatinib yaive nekukura kwakakura inhibitory mhedzisiro paHer-2 overexpressing cancer cancer cell mitsara.MuChikamu I miedzo yegomarara rezamu repamusoro neHer-2 overexpression, Lapatinib zvakare ine mwero wepamusoro unoshanda uye haina kupesana neHerceptin (trastuzumab).Nekuti chimiro chayo imorekuru diki, kusiyana neHerceptin (trastuzumab), inogona kupinda muropa-uropi chinovharira uye ine imwe nzira yekurapa pahuropi metastasis yegomarara rezamu.
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