4-Chloro-6-Iodoquinazoline CAS 98556-31-1 Kuchena >98.0% (HPLC)

Tsanangudzo Pfupi

Zita reKemikari: 4-Chloro-6-Iodoquinazoline

CAS: 98556-31-1

Kuchena:> 98.0% (HPLC)

Chitarisiko: Earth Yellow kusvika Yellowish-Brown Powder

Pakati peLapatinib / Lapatinib Ditosylate Monohydrate

Bata: Dr. Alvin Huang

Nharembozha/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira kugadzira 4-Chloro-6-Iodoquinazoline (CAS: 98556-31-1) ine mhando yepamusoro.Ruifu Chemical inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, sevhisi yakanakisa, idiki uye yakawanda huwandu huripo.Tenga 4-Chloro-6-Iodoquinazoline,Please contact: alvin@ruifuchem.com

Lapatinib Intermediates:

Lapatinib Base	CAS 231277-92-2
Lapatinib Ditosylate Monohydrate	CAS 388082-78-8
Sodium methanesulfinate	CAS 20277-69-4
3-Chloro-4-(3-Fluorobenzyloxy)aniline	CAS 202197-26-0
2-Aminoethyl Methyl Sulfone Hydrochloride	CAS 104458-24-4
4-Chloro-6-Iodoquinazoline	CAS 98556-31-1
6-Iodo-4-Hydroxyquinazoline	CAS 16064-08-7
5-Formyl-2-Furanboronic Acid	CAS 27329-70-0
5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde	CAS 231278-84-5

Chemical Properties:

Chemical Name	4-Chloro-6-Iodoquinazoline
Mashoko anoreva zvakafanana	6-Iodo-4-Chloroquinazoline
Stock Status	MuStock, Commercial Production
Nhamba yeCAS	98556-31-1
Molecular Formula	C8H4ClIN2
Molecular Weight	290.49 g/mol
Melting Point	175.0 kusvika 179.0 ℃
Density	2.017±0.06 g/cm3
Refractive Index n20/D	1.739
Sensitive	Air Sensitive
COA & MSDS	Available
Origin	Shanghai, China
Brand	Ruifu Chemical

Zvinotsanangurwa:

Items	Kuongorora Maitiro	Results
Chitarisiko	Earth Yellow kusvika Yellowish-Brown Powder	Earth Yellow Powder
Melting Point	175.0 kusvika 179.0 ℃	177.2℃
Kurasika paKuomesa	<1.00%	0.15%
Kuchena / Analysis Method	>98.0% (HPLC)	98.43%
1H NMR Spectrum	Zvinoenderana NeChimiro	Zvinoenderana
Mhedziso	Chigadzirwa chakaedzwa uye chinoenderana nezvakapihwa
Application	Pakati peLapatinib / Lapatinib Ditosylate Monohydrate

Pakeji/Kuchengeta/Shipping:

Package:Fluorinated Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mudziyo wakavharwa zvakasimba uye chengeta muimba inotonhorera, yakaoma uye ine mhepo yakanaka kure nezvinhu zvisingaenderani.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.

Zvakanakira:

Yakakwana Capacity: Inokwana zvivakwa uye matekiniki

Professional Service: Imwe inomira kutenga sevhisi

OEM Package: Tsika pasuru uye label iripo

Fast Delivery: Kana iri mukati me stock, mazuva matatu ekutumira anovimbiswa

Yakagadzika Supply: Chengetedza zvine musoro stock

Tsigiro yehunyanzvi: Tekinoroji mhinduro iripo

Tsika Synthesis Service: Kubva pamagiramu kusvika makirogiramu

Hunhu Hwepamusoro: Yakagadzira yakakwana yemhando yekusimbisa system

FAQ:

Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.

98556-31-1 - Application:

4-Chloro-6-Iodoquinazoline (CAS: 98556-31-1) iri pakati pekugadzirisa kweLapatinib (CAS: 231277-92-2) / Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8).
Lapatinib itsva yekenza yemazamu yakanangwa mushonga wekurapa wakagadzirwa uye wakagadzirwa neGlaxoSmithKline, iyo yakatenderwa neUS Food and Drug Administration musi waKurume 13, 2007. Chiratidzo chazvino chakabvumidzwa chinosanganiswa ne capecitabine yekenza yepamusoro kana metastatic yemazamu, uye varwere vekenza yemazamu. inofanira kurapwa nemimwe mishonga yekutanga.Zita rayo rekutengeserana muUnited States ndiTykerb.Musi waZvita 14, 2007, European Medicines Agency (EMEA) yakabvumidza kunyorwa kweLapatinib muEurope pasi pezita rekutengesa Tyverb.Molecular yakanangwa kurapwa kwegomarara rezamu inoreva kurapwa kweoncogenes uye zvine chekuita nekutaura zvigadzirwa zvine chekuita nekuitika uye kukura kwegomarara rezamu.Molecular yakanangwa zvinodhaka inhibisa kana kuuraya bundu maseru nekuvharira kutapurirana chiratidzo mumamota maseru kana maseru ane hukama kudzora shanduko musero gene kutaura.Lapatinib ndeyemuromo diki molecule epidermal kukura factor tyrosine kinase inhibitor.Miedzo yemakiriniki yakaratidza kuti kune HER2 varwere vekenza yemazamu avo vakatanga kuramba Roche's Herceptin (Herceptin), Lapatinib ine yakanaka kiriniki mhedzisiro.In vitro bvunzo, Lapatinib yaive nekukura kwakakura inhibitory mhedzisiro paHer-2 overexpressing cancer cancer cell mitsara.MuChikamu I miedzo yegomarara rezamu repamusoro neHer-2 overexpression, Lapatinib zvakare ine mwero wepamusoro unoshanda uye haina kupesana neHerceptin (trastuzumab).Nekuti chimiro chayo imorekuru diki, kusiyana neHerceptin (trastuzumab), inogona kupinda muropa-uropi chinovharira uye ine imwe nzira yekurapa pahuropi metastasis yegomarara rezamu.