Cetrorelix Acetate CAS 130143-01-0 GnRH Antagonist Peptide Purity (HPLC) ≥98.0% High Quality
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira kugadzira Cetrorelix Acetate (CAS: 130143-01-0) ine mhando yepamusoro.Cetrorelix Acetate inopikisa gonadotropin-releasing hormone (GnRH).Ruifu Chemical inopa akatevedzana eGMP peptides.Ruifu inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, madiki uye akawanda akawanda aripo.Tenga Cetrorelix Acetate,Please contact: alvin@ruifuchem.com
Chemical Name | Cetrorelix Acetate |
Mashoko anoreva zvakafanana | N-Acetyl-3-(2-Naphthalenyl)-D-Alanyl-4-Chloro-D-Phenylalanyl-3-(3-Pyridinyl)-D-Alanyl-L-Seryl-L-Tyrosyl-N5-(Aminocarbonyl)- D-Ornithyl-L-Leucyl-L-Arginyl-L-Prolyl-D-Alaninamide Diacetate;NS-75A Diacetate;SB-075 Diacetate |
Sequences | Ac-3-(2-naphthyl)-D-Ala-4-Chloro-D-Phe-3(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala -NH2 |
Nhamba yeCAS | 130143-01-0 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Makirogiramu |
Molecular Formula | C70H92N17O14 |
Molecular Weight | 1551.16 |
Storage Temp. | Nzvimbo Inotonhorera & Yakaoma (-20 ℃).Firiji |
Sherufu Hupenyu | > 2 Makore Kana Akachengetwa Zvakanaka |
Category | GMP Peptides |
Gwaro | COA, MS, HPLC, NMR, MSDS, nezvimwe. |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | White Powder |
Peptide Purity (neHPLC) | ≥98.0% (neArea Integration) |
Peptide Content | ≥80.0% (ne%N) |
Amino Acid Kuumbwa | 10% yeTheetical |
Acetate Content | ≤10.0% (neHPLC) |
TFA Content | ≤1.0% |
Kusachena Kumwechete | ≤1.0% (neHPLC) |
Zvemumvura (Karl Fischer) | ≤8.0% |
Assay | 95.0~105.0% (NeAnhydrous, Acetic Acid-Isina) |
MS | Consistent |
Test Standard | Enterprise Standard |
Kutumira Zvinodiwa | Ice Mabhegi, Desiccant Mabhegi |
Origin of Product | Synthetic |
Attention | Chete Chekutsvaga, Kwete Chekushandisa Vanhu |
Usage | Synthetic Antagonist yeGnRH Receptor |
Package:Plastic vial (yakatsaurirwa peptide kurongedza) kana girazi vial, huwandu hunoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma (2~8℃) yekuchengetera kure nezvinhu zvisingaenderane.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.
Cetrorelix Acetate (CAS 130143-01-0) is a gonadotropin-releasing hormone (GnRH) antagonist inotengeswa zvakanyanya pasi pezita rechiratidzo Cetrotide.A synthetic decapeptide, inoshandiswa mukubatsira kubereka kudzivirira nguva isati yakwana luteinizing hormone surges.Mushonga unoshanda nekuvhara chiito cheGnRH pane pituitary, nokudaro nekukurumidza kudzvinyirira kugadzirwa uye chiito che luteinizing hormone (LH) uye follicle-stimulating hormone (FSH).Cetrorelix Acetate inoumbwa neakasiyana-siyana asiri echisikigo amino acids anodzivirira kutanga ovulation mumakiriniki ekuedzwa, zvichitungamira mukuunganidza ovulation uye kubatsira kubereka tekinoroji kurapwa kune varwere vanodzorwa ovarian kukurudzira.
Chiratidzo Cetrorelix Acetate ihomoni yakagadzirwa inovhara mhedzisiro yegonadotropin-inoburitsa hormone (GnRH).Mukubatsira tekinoroji yekubereka, mune varwere vane inodzorwa ovarian kukurudzira, kudzivirira nguva isati yakwana ovulation.
Pharmacological action Cetrorelix Acetate mupikisi wegonadotropin-releasing hormone (GnRH).GnRH inogona kusunga kune membrane receptors yepituitary masero.Cetrorelix acetate inosungirirana kune aya ma receptors ane endogenous GnRH, nekudaro dose-inoenderana nekuvharira secretion ye luteinizing hormone (LH) uye follicle stimulating hormone (FSH) neadenohypophysis.Iyo inhibitory effect yakabudiswa pakarepo mushure mekutonga kwecetrorelix acetate, uye inhibitory effect inogona kuchengetedzwa nekuenderera mberi kwekurapa.kune vakadzi, Cetrorelix Acetate inogona kunonoka iyo LH peak, nekudaro kunonoka ovulation.Kune vakadzi vari kukurudzirwa ovarian, nguva yekuita yaienderana nedosi.Chirwere chimwe chete che cetrorelix 3mg yaifungidzirwa kuva inhibitory effect yemazuva mashoma 4, ine inhibitory effect inenge 70% paZuva 4. Kudzokororwa kwekutonga kwe cetrorelix acetate 0.25mg maawa ose e24 inogona kuchengetedza kushanda kwayo.Iyo hormone-inopikisa mhedzisiro yeCetrorelix Acetate yakadzoserwa zvachose pakupera kwekurapa mumhuka nevanhu.
Biological chiitiko Cetrorelix Acetate mupikisi ane simba weGnRH receptor ine IC50 kukosha kwe1.21 nM.
Chinangwa IC50: 1.21 nM GnRH.