Cetrorelix Acetate CAS 130143-01-0 GnRH Antagonist Peptide Purity (HPLC) ≥98.0% High Quality

Tsanangudzo Pfupi

Zita reKemikari: Cetrorelix Acetate

CAS: 130143-01-0

Kuonekwa: White Powder

Peptide Purity (HPLC): ≥98.0%

Synthetic Antagonist yeGnRH Receptor

GMP Peptides, API, High Quality

Bata: Dr. Alvin Huang

Nharembozha/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com 


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Tsanangudzo:

Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira kugadzira Cetrorelix Acetate (CAS: 130143-01-0) ine mhando yepamusoro.Cetrorelix Acetate inopikisa gonadotropin-releasing hormone (GnRH).Ruifu Chemical inopa akatevedzana eGMP peptides.Ruifu inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, madiki uye akawanda akawanda aripo.Tenga Cetrorelix Acetate,Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name Cetrorelix Acetate
Mashoko anoreva zvakafanana N-Acetyl-3-(2-Naphthalenyl)-D-Alanyl-4-Chloro-D-Phenylalanyl-3-(3-Pyridinyl)-D-Alanyl-L-Seryl-L-Tyrosyl-N5-(Aminocarbonyl)- D-Ornithyl-L-Leucyl-L-Arginyl-L-Prolyl-D-Alaninamide Diacetate;NS-75A Diacetate;SB-075 Diacetate
Sequences Ac-3-(2-naphthyl)-D-Ala-4-Chloro-D-Phe-3(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala -NH2
Nhamba yeCAS 130143-01-0
Stock Status MuStock, Kugadzirwa Kunokwira Kusvika Makirogiramu
Molecular Formula C70H92N17O14
Molecular Weight 1551.16
Storage Temp. Nzvimbo Inotonhorera & Yakaoma (-20 ℃).Firiji
Sherufu Hupenyu > 2 Makore Kana Akachengetwa Zvakanaka
Category GMP Peptides
Gwaro COA, MS, HPLC, NMR, MSDS, nezvimwe.
Brand Ruifu Chemical

Zvinotsanangurwa:

Item Zvinotsanangurwa
Chitarisiko White Powder
Peptide Purity (neHPLC) ≥98.0% (neArea Integration)
Peptide Content ≥80.0% (ne%N)
Amino Acid Kuumbwa 10% yeTheetical
Acetate Content ≤10.0% (neHPLC)
TFA Content ≤1.0%
Kusachena Kumwechete ≤1.0% (neHPLC)
Zvemumvura (Karl Fischer) ≤8.0%
Assay 95.0~105.0% (NeAnhydrous, Acetic Acid-Isina)
MS Consistent
Test Standard Enterprise Standard
Kutumira Zvinodiwa Ice Mabhegi, Desiccant Mabhegi
Origin of Product Synthetic
Attention Chete Chekutsvaga, Kwete Chekushandisa Vanhu
Usage Synthetic Antagonist yeGnRH Receptor

Package & Kuchengeta:

Package:Plastic vial (yakatsaurirwa peptide kurongedza) kana girazi vial, huwandu hunoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma (2~8℃) yekuchengetera kure nezvinhu zvisingaenderane.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.

Zvakanakira:

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Application:

Cetrorelix Acetate (CAS 130143-01-0) is a gonadotropin-releasing hormone (GnRH) antagonist inotengeswa zvakanyanya pasi pezita rechiratidzo Cetrotide.A synthetic decapeptide, inoshandiswa mukubatsira kubereka kudzivirira nguva isati yakwana luteinizing hormone surges.Mushonga unoshanda nekuvhara chiito cheGnRH pane pituitary, nokudaro nekukurumidza kudzvinyirira kugadzirwa uye chiito che luteinizing hormone (LH) uye follicle-stimulating hormone (FSH).Cetrorelix Acetate inoumbwa neakasiyana-siyana asiri echisikigo amino acids anodzivirira kutanga ovulation mumakiriniki ekuedzwa, zvichitungamira mukuunganidza ovulation uye kubatsira kubereka tekinoroji kurapwa kune varwere vanodzorwa ovarian kukurudzira.
Chiratidzo Cetrorelix Acetate ihomoni yakagadzirwa inovhara mhedzisiro yegonadotropin-inoburitsa hormone (GnRH).Mukubatsira tekinoroji yekubereka, mune varwere vane inodzorwa ovarian kukurudzira, kudzivirira nguva isati yakwana ovulation.
Pharmacological action Cetrorelix Acetate mupikisi wegonadotropin-releasing hormone (GnRH).GnRH inogona kusunga kune membrane receptors yepituitary masero.Cetrorelix acetate inosungirirana kune aya ma receptors ane endogenous GnRH, nekudaro dose-inoenderana nekuvharira secretion ye luteinizing hormone (LH) uye follicle stimulating hormone (FSH) neadenohypophysis.Iyo inhibitory effect yakabudiswa pakarepo mushure mekutonga kwecetrorelix acetate, uye inhibitory effect inogona kuchengetedzwa nekuenderera mberi kwekurapa.kune vakadzi, Cetrorelix Acetate inogona kunonoka iyo LH peak, nekudaro kunonoka ovulation.Kune vakadzi vari kukurudzirwa ovarian, nguva yekuita yaienderana nedosi.Chirwere chimwe chete che cetrorelix 3mg yaifungidzirwa kuva inhibitory effect yemazuva mashoma 4, ine inhibitory effect inenge 70% paZuva 4. Kudzokororwa kwekutonga kwe cetrorelix acetate 0.25mg maawa ose e24 inogona kuchengetedza kushanda kwayo.Iyo hormone-inopikisa mhedzisiro yeCetrorelix Acetate yakadzoserwa zvachose pakupera kwekurapa mumhuka nevanhu.
Biological chiitiko Cetrorelix Acetate mupikisi ane simba weGnRH receptor ine IC50 kukosha kwe1.21 nM.
Chinangwa IC50: 1.21 nM GnRH.

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