Cyano-Irbesartan CAS 138401-24-8 Kuchena > 98.0% (HPLC) Irbesartan Intermediate Factory
Ruifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Trityl Irbesartan CAS 138402-10-5
TTBB CAS 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1
Chemical Name | Cyano-Irbesartan |
Mashoko anoreva zvakafanana | CyanoIrbesartan;Irbesartan Cyano Impurity;Irbesartan Hydrocarbon;Irbesartan Kusachena 6;2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-one;4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4,4]non-1-en-3-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile |
Nhamba yeCAS | 138401-24-8 |
Nhamba yeCAT | RF-PI1892 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
Molecular Formula | C25H27N3O |
Molecular Weight | 385.51 |
Density | 1.15 |
Solubility (Soluble in) | Methanol |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Ichena kusvika Kunenge Ichena Hupfu kusvika kuCrystal |
Kuchena / Analysis Method | >98.0% (HPLC) |
Kuchena | >97.0% (NeNitrogen Yese) |
Melting Point | 91.0 kusvika 95.0 ℃ |
Kurasika paKuomesa | <1.00% |
Kusachena Kumwechete | <1.00% |
Heavy Metals | <20ppm |
Infrared Spectrum | Inopindirana neChimiro |
Test Standard | Enterprise Standard |
Usage | Pakati / Kusachena kweIrbesartan (CAS: 138402-11-6) |
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro
Cyano-Irbesartan (CAS: 138401-24-8) iri pakati kana kusachena kweIrbesartan (CAS: 138402-11-6).Irbesartan inonzi angiotensin II (Angiotensin II, Ang II) receptor inhibitor.Angiotensin II receptors yakakamurwa kuva marudzi maviri: AT1 uye AT2.Irbesartan inosarudza kuvhara iyo AT1 receptor yeAnglI.Iyo inogona kumisa kushandurwa kweAng kuita Ang, inogona kunyanya kupikisa iyo angiotensin-inoshandura enzyme 1 receptor (AT1).Mhedzisiro yekupikisa paAT1 ndeye 8500 nguva yeAT2.Inogona kusarudza kuvharira kusungwa kweAng uye AT1 receptor kuburikidza neInhibit vasoconstriction uye kuburitswa kwealdosterone, zvichikonzera hypotensive effect.Ichi chigadzirwa hachidziviriri angiotensin inoshandura enzyme (ACE), renin, mamwe mahormone receptors, uye haidziviriri nzira dzeion dzine chekuita nekudzora kweropa uye sodium chiyero.Irbesartan inogona zvakare kuderedza kugadziridzwa kwemagetsi kwemyocardium, nekudaro ichidzikisa huwandu hwekufa kwevarwere vane hypertension.Parizvino ndiyo inonyanya kushanda mushonga wekurapa hypertension uye chirwere chemoyo.