α-Cyclodextrin (α-CD) CAS 10016-20-3 Pharmaceutical Excipients
Ruifu Chemical ndiyo inotungamira kugadzira α-Cyclodextrin (α-CD) (CAS: 10016-20-3) ine mhando yepamusoro.Ruifu Chemical inopa pharma giredhi cyclodextrins, mishonga excipients.Ruifu Chemical inogona kupa kutumirwa kwepasirese, kudiki uye kuwanda huwandu huripo.Tenga α-Cyclodextrin,Please contact: alvin@ruifuchem.com
Chemical Name | α-Cyclodextrin |
Mashoko anoreva zvakafanana | α-CD;C;Alfadex;alpha-Dextrin;α-Dextrin;Cyclohexapentylose;Cavamax W6;Schardinger α-Dextrin;α-Schardinger Dextrin;Schardinger alpha-Dextrin;Cyclomaltohexaose;Cyclohexaamylose |
Stock Status | MuStock, Commercial Production |
Nhamba yeCAS | 10016-20-3 |
Molecular Formula | C |
Molecular Weight | g/mol |
Melting Point | >278℃(December) (lit.) |
Boiling Point | ℃ |
Flash Point | ℃ |
Density | |
Refractive Index n20/D | 1 |
Sensitive | Hygroscopic.Mhepo Inonzwa, Chiedza Chinonzwisiswa, Kunyorova |
Mvura Solubility | Soluble mumvura |
Solubility | Soluble in |
Kugadzikana | Yakagadzikana.Inopisa.Haienderane Neakasimba Oxidizing Agents. |
COA & MSDS | Available |
Yemahara Muenzaniso | Available |
Origin | Shanghai, China |
Category | Pharmaceutical Excipients;Zvokudya zvinowedzera |
Brand | Ruifu Chemical |
Items | Zvinotsanangurwa | Results |
Chitarisiko | Ichena kana Inenge Ichena Amorphous kana Crystalline Powder | Conforms |
Solubility | Inonyungudika Zvakasununguka muMvura uye muPropylene Glycol, Isingasviki muEthanol uye muMethylene Chloride. | Conforms |
ldentification HPLC | Nguva yekuchengetedza yepamusoro pepamusoro yemuenzaniso mhinduro inoenderana neyakajairwa mhinduro. | Conforms |
Iodine Test Solution | Yellow-Brown Precipitate Yakagadzirwa | Conforms |
Assay | 98.0% ~ 101.0% (Yakaverengerwa pane Yakaomeswa Basis) | 100.0% |
Kutenderera kwakananga [a]20/D | +147.0° kusvika +152.0°(C=1 muH2O) (Calcd. paAnh. Substance) | +148.2° |
Kujeka & Rudzi rweKugadzirisa | 10mg/ml Mvura Solution Yakajeka uye isina Ruvara | Conforms |
Muganhu weChiedza-Absorbing Substances | ≤0.10 (230 nm~350 nm) ≤0.05 (350 nm~750 nm) | Conforms |
Kutsunga Mvura | ≤11.0% | 9.9% |
Residue paIgnition | ≤0.10% | 0.07% |
Heavy Metals | ≤5ppm | <5ppm |
Arsenic Munyu (Se) | ≤1.3ppm | <1.3ppm |
Kuderedza Shuga | ≤0.20% | 0.16% |
Related Substances | ||
Betadex Cyclodextrin | ≤0.25% | N/D |
Gamma Cyclodextrin | ≤0.25% | N/D |
Zvimwe Zvinoenderana Nezvinhu | ≤0.50% | N/D |
pH | 5.0~8.0 | 6.2 |
Microbiological Test | ||
Total Aerobic Microbial Counts | ≤1000cfu/g | 30cfu/g |
Total Molds & Yeasts Counts | ≤50cfu/g | <50cfu/g |
Escherichia Coli | Absent | Absent |
Salmonella | Absent | Absent |
Infrared Spectrum | Inopindirana neChimiro | Conforms |
Test Standard | USP41-NF36 |
Package:0.5kg// bag, 1kg/bag, 2kg/bag,10kg/bag, 25kg/Drum, kana maererano nezvinodiwa nemutengi.
Storage Condition:Chengetedza mudziyo wakavharwa zvakasimba uye chengeta muimba inotonhorera, yakaoma uye ine mhepo yakanaka kure nezvinhu zvisingaenderani.Dzivirira kubva kuchiedza uye unyoro.Hazvienderani neakasimba oxidizing agents.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.
Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
Hazard Symbols Xi - Irritant
Risk Codes R36 - Kushungurudza maziso
R36/37/38 - Kushungurudza maziso, kufema system uye ganda.
Tsanangudzo Yekuchengetedza S26 - Kana wasangana nemaziso, sukurudza nekukurumidza nemvura yakawanda uye tsvaga mazano ekurapwa.
S36 - Pfeka zvipfeko zvinodzivirira zvakakodzera.
WGK Germany 3
RTECS GU2292000
TSCA Hongu
HS Code 3505100000
α-Cyclodextrin (α-CD) (CAS: 10016-20-3)isiri-kuderedza cyclic saccharide inoumbwa nezvikamu zvitanhatu zveglucose zvakabatanidzwa nealpha-1.4 bond.Inogadzirwa nekuita kwe cyclodextrin glucosyl transferase pane hydrolysed starch syrups.Iyo mhango ye alpha-Cyclodextrin ishoma pane beta-Cyclodextrin, saka inoshandiswa kubvumira kuumbwa kwekubatanidza macomplexes ane mamorekuru madiki.Iyo solubility degree yeAlpha-Cyclodextrin mumvura i14.5 g/100ml @25°C, saka mamiriro anoda kunyungudika kwakanyanya kwe cyclodextrin.
Alpha-cyclodextrin inoshandiswa zvakanyanya mumishonga, chikafu, flavour uye cosmetics.Alpha-cyclodextrin inoshandiswawo zvakanyanya mumunda wemishonga yezvipembenene uye kugadzirisa metabolization yechirimwa uye kuwedzera huwandu hwechirimwa.Kunyanya iyo cyclodextrin uye ramification yayo yakagadziridzwa nemakore aya, mamwe acho ndiwo akakosha solutizer, stablizer, kuburitsa kana zvinhu zvekubatsira zveEntericcoated zvinodhaka, zvimwe zvacho zvinhu zveorganic synthetical macromolecular zvinhu.
Chikafu giredhi Alpha cyclodextrin ine 6 glucose mayunitsi ane diki mhango yemubereki cyclodextrins.Inobatsira pakunyorovesa, kudzikamisa kana kuendesa mamorekuru madiki, eg low molecular weight, flavour or fragrance compounds.Chikafu chegiredhi Alpha cyclodextrin iri kuunzwa kuindasitiri yezvekudya sechinhu chitsva chinonyungudika chekudya chine hunhu hunogutsa.
Cyclodextrin ine gomba pakati pechimiro chemhete, uye atomu yeokisijeni umo -CH- inosunga glucoside.Iyo ine sulfur-aqueous, uye mapoka ehydroxyl pa2, 3 uye 6 nzvimbo dzeglucose ane hydrophilic.Inogona kushandiswa kuomesera mamwe mamorekuru kuita macomplexes anosanganisirwa neasina simba van der Waals simba.Zvinhu zvakawanda zvinogona kuvharidzirwa ne cyclodextrins, kusanganisira gasi rakanaka, halogens, dhayi, zvinonhuwira, mishonga, zvokudya, mishonga yezvipembenene uye zvinodzivirira.Mushure mekuvhara, kugadzikana kwayo, kusagadzikana, solubility uye reactivity inovandudzwa.Iyo yakakosha mhedzisiro yeCyclodextrin inoita kuti ive yakashandiswa zvakanyanya encapsulation zvinhu.
1. Kushandiswa kweCyclodextrin mumhizha yemishonga inogona kuumba encapsulation (encapsulation) nemishonga, iyo inogona kuita (1) Mishonga isina kugadzikana yakasimba;(2) Deliquescence, adhesion kana liquid drug powderization;(3) Insoluble kana insoluble zvinodhaka zvinogona kunyungudutswa (solubilized), nezvimwewo.
2. Kushandiswa muindasitiri yemishonga yezvipembenene cyclodextrin encapsulation stabilization, mamwe mishonga yezvipembenene inogona kuchengetwa nekuvandudza kushanda kwezvipembenene.
3. Inoshandiswa mumhizha yezvokudya cyclodextrin inoshandiswa mumhizha yezvokudya, ine migumisiro inotevera: (1) Kubvisa uye kuvhara kunhuhwirira kwakakosha;(2) Kuvandudzwa nekuvandudzwa kwechimiro chenyama yechikafu;(3) kuderedza uye kubvisa kuravira kunovava;(4) Antioxidant effect;(5) Kuchengetedza uye optimization yekunaka.
4. Kushandiswa kweCyclodextrin mukugadzirwa kwemakemikari ezuva nezuva mukugadzirwa kwezvizoro kunogonawo kushandiswa se emulsifier uye inovandudza kunaka.Iyo zvakare ine deodorization (yakadai sekuwedzera kune halitosis) uye antiseptic mhedzisiro, inogona kushandiswa mushonga wemazino, mazino poda kugadzira.
5. Zvimwe zvinoshandiswa mukuchengetedzwa kwezvakatipoteredza zvinogona kushandiswa semugadziri wekurapa wemafuta emarara.Iyo aqueous solution yeCyclodextrin inoshandiswa kuchenesa tangi remafuta, uye tsvina yemvura inogona kudzoserwa uye kurapwa kuti iwane mafuta emafuta.
6. Kushandiswa kwe cyclodextrin mumakemikari Cyclodextrin inokosha yemakemikari reagent.Kana iripo, iyo fluorescence intensity yefluorochrome ichawedzera zvakanyanya, saka inogona kushandiswa pakuongorora mapuroteni uye amino acids.Inogona zvakare kushandiswa kuparadzanisa refu cheni organic komisheni, racemes, nezvimwe.
Mukuwedzera, iyo adsorbent yakagadzirwa kubva kuCyclodextrin inogona kushandiswa chromatographic adsorption.
Basa
1. α-Cyclodextrin Wedzera kugadzikana kwezvinhu: Dzivirira kuputika, kudzivirira kuderera;Anti-oxidation;Kudzivirira kuora kwe optothermal;Anti kuparara kwemakemikari;Wedzera nguva yekushanda kwezvinhu.
2. α-Cyclodextrin Wedzera kunyungudika kwezvinhu uye bioavailability.
3. α-Cyclodextrin kuburikidza nekugadzirwa kwekubatanidzwa kwakaoma kuti ibudirire chivharo chinonhuwira chinonhuwira.
4. α-Cyclodextrin Liquid mushonga muhutano hwakasimba.
5. α-Cyclodextrin Kudzivirira zvinodhaka - zvinodhaka, zvinodhaka - kusangana pakati pekuwedzera.
6. α-Cyclodextrin Deredza migumisiro yechirwere.
Application
1. α-Cyclodextrin inoshandiswa kuwedzera kugadzikana kwezvinhu: Kudzivirira kuputika, kudzivirira kuderera;Anti-oxidation;
2. α-Cyclodextrin inoshandiswa kudzivirira kuora kwe optothermal;Anti kuparara kwemakemikari;Wedzera nguva yekushanda kwezvinhu.
3. α-Cyclodextrin inoshandiswa kuwedzera kunyungudika kwezvinhu uye bioavailability.
4. Kuburikidza nekugadzirwa kweiyo inclusion complex kuti iwane chifukidziro chinonhuhwirira chinonhuwira.Mushonga wemvura kupinda muchimiro chakasimba.
5. α-Cyclodextrin inoshandiswa kudzivirira zvinodhaka - zvinodhaka, zvinodhaka - kusangana pakati pekuwedzera.
6. α-Cyclodextrin inoshandiswa kuderedza migumisiro.
Pharmaceutical:
1. Kuwedzera kunyungudika kwekuwanikwa kwebiological
2. Kuvandudza bioavailability
3. Kugadzirisa kana kudzora kusunungurwa
4. Kuderedza chepfu
5. Kuvandudza kugadzikana
Cosmetic:
1. Kuti zvienderane ne encapsulation ye volatile compounds.
2. Kuwedzera hupenyu hwesherufu hwezvinodhura zvinonaka.
Chikafu:
1.Kudzivirira kubuda kwezvinhu zvinoputika.
2.Kubvisa kunhuwa kunotyisa.
3.Kuwedzera zvakanyanya mhedzisiro ye emulsification
α-Cyclodextrin inowanikwa kuumba yakasimba yakaoma nemafuta ekudya.Nenzira iyi inoderedza bioavailability uye kunyura kwemafuta.Iyo inozivikanwa kudzora triglyceride uye leptin mazinga muserum.Mune makonzo mhando, α-Cyclodextrin inoratidzwa kuti iite insulin senitivity uye fecal mafuta excretion.Saka, α-Cyclodextrin inoonekwa seinoshanda pakurapa kufutisa uye metabolic syndromes.
Inosanganisirwa muFDA Inactive Ingredients Database: α-Cyclodextrin (majekiseni ekugadzirira);β-Cyclodextrin (mahwendefa emuromo, topical gels);γ-Cyclodextrin (IV jekiseni).Inosanganisirwa muCanada Rondedzero Yezvinogamuchirwa Zvisiri-Mushonga Ingredients (kudzikamisa agent; solubilizing agent);uye mune oral and rectal pharmaceutical formulations ane rezinesi muEurope, Japan, uye USA.