α-Cyclodextrin (α-CD) CAS 10016-20-3 Pharmaceutical Excipients

Tsanangudzo Pfupi

Kemikari Zita: α-Cyclodextrin

Mazwi akafanana: α-CD;alpha-Cyclodextrin

CAS: 10016-20-3

Chiyero: 98.0% ~ 101.0%

Ichena kana Inenge Ichena Amorphous kana Crystalline Powder

Pharmaceutical Excipients, High Quality

Bata: Dr. Alvin Huang

Nharembozha/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Tsanangudzo:

Ruifu Chemical ndiyo inotungamira kugadzira α-Cyclodextrin (α-CD) (CAS: 10016-20-3) ine mhando yepamusoro.Ruifu Chemical inopa pharma giredhi cyclodextrins, mishonga excipients.Ruifu Chemical inogona kupa kutumirwa kwepasirese, kudiki uye kuwanda huwandu huripo.Tenga α-Cyclodextrin,Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name α-Cyclodextrin
Mashoko anoreva zvakafanana α-CD;C;Alfadex;alpha-Dextrin;α-Dextrin;Cyclohexapentylose;Cavamax W6;Schardinger α-Dextrin;α-Schardinger Dextrin;Schardinger alpha-Dextrin;Cyclomaltohexaose;Cyclohexaamylose
Stock Status MuStock, Commercial Production
Nhamba yeCAS 10016-20-3
Molecular Formula C
Molecular Weight g/mol
Melting Point >278℃(December) (lit.)
Boiling Point
Flash Point
Density  
Refractive Index n20/D 1
Sensitive Hygroscopic.Mhepo Inonzwa, Chiedza Chinonzwisiswa, Kunyorova
Mvura Solubility Soluble mumvura
Solubility Soluble in
Kugadzikana Yakagadzikana.Inopisa.Haienderane Neakasimba Oxidizing Agents.
COA & MSDS Available
Yemahara Muenzaniso Available
Origin Shanghai, China
Category Pharmaceutical Excipients;Zvokudya zvinowedzera
Brand Ruifu Chemical

Zvinotsanangurwa:

Items Zvinotsanangurwa Results
Chitarisiko Ichena kana Inenge Ichena Amorphous kana Crystalline Powder Conforms
Solubility Inonyungudika Zvakasununguka muMvura uye muPropylene Glycol, Isingasviki muEthanol uye muMethylene Chloride. Conforms
ldentification HPLC Nguva yekuchengetedza yepamusoro pepamusoro yemuenzaniso mhinduro inoenderana neyakajairwa mhinduro. Conforms
Iodine Test Solution Yellow-Brown Precipitate Yakagadzirwa Conforms
Assay 98.0% ~ 101.0% (Yakaverengerwa pane Yakaomeswa Basis) 100.0%
Kutenderera kwakananga [a]20/D +147.0° kusvika +152.0°(C=1 muH2O) (Calcd. paAnh. Substance) +148.2°
Kujeka & Rudzi rweKugadzirisa 10mg/ml Mvura Solution Yakajeka uye isina Ruvara Conforms
Muganhu weChiedza-Absorbing Substances ≤0.10 (230 nm~350 nm) ≤0.05 (350 nm~750 nm) Conforms
Kutsunga Mvura ≤11.0% 9.9%
Residue paIgnition ≤0.10% 0.07%
Heavy Metals ≤5ppm <5ppm
Arsenic Munyu (Se) ≤1.3ppm <1.3ppm
Kuderedza Shuga ≤0.20% 0.16%
Related Substances    
Betadex Cyclodextrin ≤0.25% N/D
Gamma Cyclodextrin ≤0.25% N/D
Zvimwe Zvinoenderana Nezvinhu ≤0.50% N/D
pH 5.0~8.0 6.2
Microbiological Test    
Total Aerobic Microbial Counts ≤1000cfu/g 30cfu/g
Total Molds & Yeasts Counts ≤50cfu/g <50cfu/g
Escherichia Coli Absent Absent
Salmonella Absent Absent
Infrared Spectrum Inopindirana neChimiro Conforms
Test Standard USP41-NF36

Pakeji/Kuchengeta/Shipping:

Package:0.5kg// bag, 1kg/bag, 2kg/bag,10kg/bag, 25kg/Drum, kana maererano nezvinodiwa nemutengi.
Storage Condition:Chengetedza mudziyo wakavharwa zvakasimba uye chengeta muimba inotonhorera, yakaoma uye ine mhepo yakanaka kure nezvinhu zvisingaenderani.Dzivirira kubva kuchiedza uye unyoro.Hazvienderani neakasimba oxidizing agents.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.

Zvakanakira:

Yakakwana Capacity: Inokwana zvivakwa uye matekiniki

Professional Service: Imwe inomira kutenga sevhisi

OEM Package: Tsika pasuru uye label iripo

Fast Delivery: Kana iri mukati me stock, mazuva matatu ekutumira anovimbiswa

Yakagadzika Supply: Chengetedza zvine musoro stock

Tsigiro yehunyanzvi: Tekinoroji mhinduro iripo

Tsika Synthesis Service: Kubva pamagiramu kusvika makirogiramu

Hunhu Hwepamusoro: Yakagadzira yakakwana yemhando yekusimbisa system

FAQ:

Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.

Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.

Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.

HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.

Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.

Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.

MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.

Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.

Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.

Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.

Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.

Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.

10016-20-3 - Information Information:

Hazard Symbols Xi - Irritant
Risk Codes R36 - Kushungurudza maziso
R36/37/38 - Kushungurudza maziso, kufema system uye ganda.
Tsanangudzo Yekuchengetedza S26 - Kana wasangana nemaziso, sukurudza nekukurumidza nemvura yakawanda uye tsvaga mazano ekurapwa.
S36 - Pfeka zvipfeko zvinodzivirira zvakakodzera.
WGK Germany 3
RTECS GU2292000
TSCA Hongu
HS Code 3505100000

10016-20-3 - Kusuma Chigadzirwa:

α-Cyclodextrin (α-CD) (CAS: 10016-20-3)isiri-kuderedza cyclic saccharide inoumbwa nezvikamu zvitanhatu zveglucose zvakabatanidzwa nealpha-1.4 bond.Inogadzirwa nekuita kwe cyclodextrin glucosyl transferase pane hydrolysed starch syrups.Iyo mhango ye alpha-Cyclodextrin ishoma pane beta-Cyclodextrin, saka inoshandiswa kubvumira kuumbwa kwekubatanidza macomplexes ane mamorekuru madiki.Iyo solubility degree yeAlpha-Cyclodextrin mumvura i14.5 g/100ml @25°C, saka mamiriro anoda kunyungudika kwakanyanya kwe cyclodextrin.

 

Alpha-cyclodextrin inoshandiswa zvakanyanya mumishonga, chikafu, flavour uye cosmetics.Alpha-cyclodextrin inoshandiswawo zvakanyanya mumunda wemishonga yezvipembenene uye kugadzirisa metabolization yechirimwa uye kuwedzera huwandu hwechirimwa.Kunyanya iyo cyclodextrin uye ramification yayo yakagadziridzwa nemakore aya, mamwe acho ndiwo akakosha solutizer, stablizer, kuburitsa kana zvinhu zvekubatsira zveEntericcoated zvinodhaka, zvimwe zvacho zvinhu zveorganic synthetical macromolecular zvinhu.

 

Chikafu giredhi Alpha cyclodextrin ine 6 glucose mayunitsi ane diki mhango yemubereki cyclodextrins.Inobatsira pakunyorovesa, kudzikamisa kana kuendesa mamorekuru madiki, eg low molecular weight, flavour or fragrance compounds.Chikafu chegiredhi Alpha cyclodextrin iri kuunzwa kuindasitiri yezvekudya sechinhu chitsva chinonyungudika chekudya chine hunhu hunogutsa.

 

10016-20-3 - Application:

Cyclodextrin ine gomba pakati pechimiro chemhete, uye atomu yeokisijeni umo -CH- inosunga glucoside.Iyo ine sulfur-aqueous, uye mapoka ehydroxyl pa2, 3 uye 6 nzvimbo dzeglucose ane hydrophilic.Inogona kushandiswa kuomesera mamwe mamorekuru kuita macomplexes anosanganisirwa neasina simba van der Waals simba.Zvinhu zvakawanda zvinogona kuvharidzirwa ne cyclodextrins, kusanganisira gasi rakanaka, halogens, dhayi, zvinonhuwira, mishonga, zvokudya, mishonga yezvipembenene uye zvinodzivirira.Mushure mekuvhara, kugadzikana kwayo, kusagadzikana, solubility uye reactivity inovandudzwa.Iyo yakakosha mhedzisiro yeCyclodextrin inoita kuti ive yakashandiswa zvakanyanya encapsulation zvinhu.
1. Kushandiswa kweCyclodextrin mumhizha yemishonga inogona kuumba encapsulation (encapsulation) nemishonga, iyo inogona kuita (1) Mishonga isina kugadzikana yakasimba;(2) Deliquescence, adhesion kana liquid drug powderization;(3) Insoluble kana insoluble zvinodhaka zvinogona kunyungudutswa (solubilized), nezvimwewo.
2. Kushandiswa muindasitiri yemishonga yezvipembenene cyclodextrin encapsulation stabilization, mamwe mishonga yezvipembenene inogona kuchengetwa nekuvandudza kushanda kwezvipembenene.
3. Inoshandiswa mumhizha yezvokudya cyclodextrin inoshandiswa mumhizha yezvokudya, ine migumisiro inotevera: (1) Kubvisa uye kuvhara kunhuhwirira kwakakosha;(2) Kuvandudzwa nekuvandudzwa kwechimiro chenyama yechikafu;(3) kuderedza uye kubvisa kuravira kunovava;(4) Antioxidant effect;(5) Kuchengetedza uye optimization yekunaka.
4. Kushandiswa kweCyclodextrin mukugadzirwa kwemakemikari ezuva nezuva mukugadzirwa kwezvizoro kunogonawo kushandiswa se emulsifier uye inovandudza kunaka.Iyo zvakare ine deodorization (yakadai sekuwedzera kune halitosis) uye antiseptic mhedzisiro, inogona kushandiswa mushonga wemazino, mazino poda kugadzira.
5. Zvimwe zvinoshandiswa mukuchengetedzwa kwezvakatipoteredza zvinogona kushandiswa semugadziri wekurapa wemafuta emarara.Iyo aqueous solution yeCyclodextrin inoshandiswa kuchenesa tangi remafuta, uye tsvina yemvura inogona kudzoserwa uye kurapwa kuti iwane mafuta emafuta.
6. Kushandiswa kwe cyclodextrin mumakemikari Cyclodextrin inokosha yemakemikari reagent.Kana iripo, iyo fluorescence intensity yefluorochrome ichawedzera zvakanyanya, saka inogona kushandiswa pakuongorora mapuroteni uye amino acids.Inogona zvakare kushandiswa kuparadzanisa refu cheni organic komisheni, racemes, nezvimwe.
Mukuwedzera, iyo adsorbent yakagadzirwa kubva kuCyclodextrin inogona kushandiswa chromatographic adsorption.

10016-20-3 - Basa uye Kushandisa:

Basa
1. α-Cyclodextrin Wedzera kugadzikana kwezvinhu: Dzivirira kuputika, kudzivirira kuderera;Anti-oxidation;Kudzivirira kuora kwe optothermal;Anti kuparara kwemakemikari;Wedzera nguva yekushanda kwezvinhu.
2. α-Cyclodextrin Wedzera kunyungudika kwezvinhu uye bioavailability.
3. α-Cyclodextrin kuburikidza nekugadzirwa kwekubatanidzwa kwakaoma kuti ibudirire chivharo chinonhuwira chinonhuwira.
4. α-Cyclodextrin Liquid mushonga muhutano hwakasimba.
5. α-Cyclodextrin Kudzivirira zvinodhaka - zvinodhaka, zvinodhaka - kusangana pakati pekuwedzera.
6. α-Cyclodextrin Deredza migumisiro yechirwere.
Application
1. α-Cyclodextrin inoshandiswa kuwedzera kugadzikana kwezvinhu: Kudzivirira kuputika, kudzivirira kuderera;Anti-oxidation;
2. α-Cyclodextrin inoshandiswa kudzivirira kuora kwe optothermal;Anti kuparara kwemakemikari;Wedzera nguva yekushanda kwezvinhu.
3. α-Cyclodextrin inoshandiswa kuwedzera kunyungudika kwezvinhu uye bioavailability.
4. Kuburikidza nekugadzirwa kweiyo inclusion complex kuti iwane chifukidziro chinonhuhwirira chinonhuwira.Mushonga wemvura kupinda muchimiro chakasimba.
5. α-Cyclodextrin inoshandiswa kudzivirira zvinodhaka - zvinodhaka, zvinodhaka - kusangana pakati pekuwedzera.
6. α-Cyclodextrin inoshandiswa kuderedza migumisiro.

10016-20-3 - Nzvimbo dzekushandisa:

Pharmaceutical:
1. Kuwedzera kunyungudika kwekuwanikwa kwebiological
2. Kuvandudza bioavailability
3. Kugadzirisa kana kudzora kusunungurwa
4. Kuderedza chepfu
5. Kuvandudza kugadzikana
Cosmetic:
1. Kuti zvienderane ne encapsulation ye volatile compounds.
2. Kuwedzera hupenyu hwesherufu hwezvinodhura zvinonaka.
Chikafu:
1.Kudzivirira kubuda kwezvinhu zvinoputika.
2.Kubvisa kunhuwa kunotyisa.
3.Kuwedzera zvakanyanya mhedzisiro ye emulsification

10016-20-3 - Biochem / Physiol Zviito:

α-Cyclodextrin inowanikwa kuumba yakasimba yakaoma nemafuta ekudya.Nenzira iyi inoderedza bioavailability uye kunyura kwemafuta.Iyo inozivikanwa kudzora triglyceride uye leptin mazinga muserum.Mune makonzo mhando, α-Cyclodextrin inoratidzwa kuti iite insulin senitivity uye fecal mafuta excretion.Saka, α-Cyclodextrin inoonekwa seinoshanda pakurapa kufutisa uye metabolic syndromes.

10016-20-3 - Regulatory Status:

Inosanganisirwa muFDA Inactive Ingredients Database: α-Cyclodextrin (majekiseni ekugadzirira);β-Cyclodextrin (mahwendefa emuromo, topical gels);γ-Cyclodextrin (IV jekiseni).Inosanganisirwa muCanada Rondedzero Yezvinogamuchirwa Zvisiri-Mushonga Ingredients (kudzikamisa agent; solubilizing agent);uye mune oral and rectal pharmaceutical formulations ane rezinesi muEurope, Japan, uye USA.

Nyora meseji yako pano uye titumire kwatiri